What we know about the mpox outbreak
The World Health Organization (WHO) has raised concerns about the emergence of Clade 1b in the Democratic Republic of Congo, which is spreading, especially among children. Though Clade 1b is not causing more severe disease, unequal vaccine distribution remains an issue. Understanding MPXV’s structure is key for improving vaccines and global health efforts.Key structural proteins of the Monkeypox virus (MPXV) are crucial for its transmission, host interaction, and immune evasion. A35R aids in transmission and is a vaccine target, while E8L, M1R, and A29L are essential for virus attachment, entry, and assembly. B6R is important for diagnostics, and D14L and H3L help the virus evade the immune system.
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