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Anti-Human IL25/IL17E Antibody (2c3)

Catalog #:   RHJ55501 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: ELISA, FCM
Accession: Q9H293
Overview

Catalog No.

RHJ55501

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Interleukin-25, IL-25, IL17E, IL25, IL-17E, Interleukin-17E

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9H293

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

2c3

Data Image
  • Bioactivity
    Detects Human IL25/IL17E in indirect ELISAs.
  • Flow-cytometry
    Flow-cytometry using anti-human IL25 antibody.PC-3 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human IL25 antibody monoclonal antibody (Catalog # RHJ55501 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # PMB96441) and cells analysed on a NovoCyte Flow Cytometer.
References

Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis., PMID:40484710

Protease-activated receptor 2 and interleukin-13 receptor α1 activation is linked to eosinophilic chronic rhinosinusitis., PMID:40074076

Interleukin-17: A pleiotropic cytokine implicated in inflammatory, infectious, and malignant disorders., PMID:39875232

Emerging biological treatments for asthma., PMID:39873193

Targeting alarmins in asthma: From bench to clinic., PMID:39855362

IL-25 Enhances B Cell Responses in Type 2 Inflammation Through IL-17RB Receptor., PMID:39829150

First-in-human study on tolerability, pharmacokinetics and pharmacodynamics of single and multiple escalating doses of XKH001, a recombinant humanized monoclonal antibody against IL-25 in healthy Chinese volunteers., PMID:39815604

Baicalein attenuates ovalbumin-induced allergic rhinitis through the activation of nuclear receptor subfamily 4 group a member 1., PMID:39808359

Evaluation of the safety, tolerability, pharmacokinetics and pharmacodynamics of SM17 in healthy volunteers: results from pre-clinical models and a first-in-human, randomized, double blinded clinical trial., PMID:39717777

Interleukin-38-overexpressing adenovirus infection in dendritic cell-based treatment enhances immunotherapy for allergic asthma via inducing Foxp3+ regulatory T cells., PMID:39667222

Protective effect of Curcuma longa L. leaves and pseudostems extract against 1-chloro-2,4-dinitrobenzene-induced atopic dermatitis in BALB/c mice., PMID:39566860

Positioning tezepelumab for patients with severe asthma: from evidence to unmet needs., PMID:39552062

[Allergy and immunotoxicology in preventive and clinical medicine from theory to practice: Environmental factors in bronchial asthma]., PMID:39537181

[The role and its regulatory significance of interleukin-25 in ovalbumin induced atopic dermatitis of mice]., PMID:39397451

Molecular Pathways and Potential Therapeutic Targets of Refractory Asthma., PMID:39194521

Therapeutic monoclonal antibodies in allergy: Targeting IgE, cytokine, and alarmin pathways., PMID:39158477

Thymic Stromal Lymphopoietin and Tezepelumab in Airway Diseases: From Physiological Role to Target Therapy., PMID:38892164

Mustard seed major allergen Sin a1 activates intestinal epithelial cells and also dendritic cells that drive type 2 immune responses., PMID:38804660

Characteristics of upper respiratory tract rhinovirus in children with allergic rhinitis and its role in disease severity., PMID:38780281

Selective production of IL-33-neutralizing autoantibody ameliorates asthma responses and severity., PMID:38740111

IL-13 protects from Clostridioides difficile colitis., PMID:38701912

The Role of OX40-OX40L Axis in the Pathogenesis of Atopic Dermatitis., PMID:38700255

Studying of anti-inflammatory and antioxidant effects of tectorigenin in ovalbumin-induced asthma mice models., PMID:38664220

Intranasal delivery of low-dose anti-CD124 antibody enhances treatment of chronic rhinosinusitis with nasal polyps., PMID:38603825

Inhibition of IL-25/IL-17RA improves immune-related adverse events of checkpoint inhibitors and reveals antitumor activity., PMID:38519059

Radical S-adenosyl methionine domain-containing 2, a potential target of D-tryptophan in asthma treatment, regulates T helper cell type 1/2 balance., PMID:38310765

Thymic stromal lymphopoietin contributes to ozone-induced exacerbations of eosinophilic airway inflammation via granulocyte colony-stimulating factor in mice., PMID:38145912

A tuft cell - ILC2 signaling circuit provides therapeutic targets to inhibit gastric metaplasia and tumor development., PMID:37898600

Serum alarmins and the risk of incident interstitial lung disease in rheumatoid arthritis., PMID:37812235

Serum cytokine profiles in myasthenia gravis with anti-muscle-specific kinase antibodies., PMID:37774555

Epithelial alarmins: a new target to treat chronic respiratory diseases., PMID:37746733

IL-25 induces airway remodeling in asthma by orchestrating the phenotypic changes of epithelial cell and fibrocyte., PMID:37635231

Effects of total alkaloids from Alstonia scholaris (L.) R. Br. on ovalbumin-induced asthma mice., PMID:37460031

A surge in serum mucosal cytokines associated with seroconversion in children at risk for type 1 diabetes., PMID:37312283

Alpha-linolenic acid improves nasal mucosa epithelial barrier function in allergic rhinitis by arresting CD4+ T cell differentiation via IL-4Rα-JAK2-STAT3 pathway., PMID:37178572

Severe asthma ILC2s demonstrate enhanced proliferation that is modified by biologics., PMID:37114915

Diagnostic Evaluation Using Salivary Gland Ultrasonography in Primary Sjögren's Syndrome., PMID:36983428

Effect of transduced mesenchymal stem cells with IL-10 gene on control of allergic asthma., PMID:36916087

Sputum Type 2 Markers Could Predict Remission in Severe Asthma Treated With Anti-IL-5., PMID:36740095

Tezepelumab for asthma., PMID:36651067

Sounding the alarmins-The role of alarmin cytokines in asthma., PMID:36463491

Antagonism of m3 Alleviates Type 2 Inflammation in Allergic Rhinitis Mice., PMID:36343939

Discovery and multi-parametric optimization of a high-affinity antibody against interleukin-25 with neutralizing activity in a mouse model of skin inflammation., PMID:36299415

Emerging roles for IL-25 and IL-33 in colorectal cancer tumorigenesis., PMID:36263033

Pulmonary Delivery of Levamisole Nanoparticles as an Immunomodulator Affecting Th and a Potential ADAM10 Inhibitor to Ameliorate Severe Allergic Asthma., PMID:36054652

Interleukin-25 enhances humoral immune responses caused by the rabies virus., PMID:35999776

Clinical and immunological characteristics of Aspergillus fumigatus-sensitized asthma and allergic bronchopulmonary aspergillosis., PMID:35983066

An innate IL-25-ILC2-MDSC axis creates a cancer-permissive microenvironment for Apc mutation-driven intestinal tumorigenesis., PMID:35658010

Dupilumab and tezepelumab in severe refractory asthma: new opportunities., PMID:35655942

Clinical and cytokine patterns of uncontrolled asthma with and without comorbid chronic rhinosinusitis: a cross-sectional study., PMID:35546400

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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For research use only. Not for human or drug use.

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Anti-Human IL25/IL17E Antibody (2c3) [RHJ55501]
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