Catalog No.
EHJ63901
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Lys580
Predicted molecular weight
61.35 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NPY3
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Matrix-remodeling-associated protein 4, C1q/MBL/SPA receptor, C1qRp, C1QR1, C1qR, Complement component 1 q subcomponent receptor 1, CD93, Complement component C1q receptor, MXRA4, CDw93, C1qR(p)
Note
For research use only.
Bioinformatics Approaches to Predict Mutation Effects in the Binding Site of the Proangiogenic Molecule CD93., PMID:36353214
Identify the immune characteristics and immunotherapy value of CD93 in the pan-cancer based on the public data sets., PMID:36389798
Identification and validation of crucial lnc-TRIM28-14 and hub genes promoting gastric cancer peritoneal metastasis., PMID:36690975
Multi-omics profiling and digital image analysis reveal the potential prognostic and immunotherapeutic properties of CD93 in stomach adenocarcinoma., PMID:36761750
Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity., PMID:36891288
The human cumulus cell transcriptome provides poor predictive value for embryo transfer outcome., PMID:36922313
Effect of avian influenza virus subtype H9N2 on the expression of complement-associated genes in chicken erythrocytes., PMID:36939295
CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin., PMID:36961390
Modelling the erythroblastic island niche of dyserythropoietic anaemia type IV patients using induced pluripotent stem cells., PMID:37113767
Extracellular vesicles from human plasma dampen inflammation and promote tissue repair functions in macrophages., PMID:37272889
CD93 Ameliorates Diabetic Wounds by Promoting Angiogenesis via the p38MAPK/MK2/HSP27 Axis., PMID:37295599
Inflammatory Mesenchymal Stem Cells Express Abundant Membrane-Bound and Soluble Forms of C-Type Lectin-like CD248., PMID:37298499
Structural insight into CD93 recognition by IGFBP7., PMID:37333140
Diagnostic and Prognostic Role of CD93 in Cardiovascular Disease: A Systematic Review., PMID:37371490
Role of CD93 in Health and Disease., PMID:37443812
CD93 overexpresses in liver hepatocellular carcinoma and represents a potential immunotherapy target., PMID:37483608
Soluble CD93 lectin-like domain sequesters HMGB1 to ameliorate inflammatory diseases., PMID:37554277
Phase I Results of Bromodomain and Extra-Terminal Inhibitor PLX51107 in Combination with Azacitidine in Patients with Relapsed/Refractory Myeloid Malignancies., PMID:37585491
The C-Type Lectin Receptor CD93 Regulates Platelet Activation and Surface Expression of the Protease Activated Receptor 4., PMID:37669782
Identification of Clinically Relevant Brain Endothelial Cell Biomarkers in Plasma., PMID:37814955
CL-K1 Promotes Complement Activation and Regulates Opsonophagocytosis of Macrophages with CD93 Interaction in a Primitive Vertebrate., PMID:38180157
Structural insight into CD93 recognition by IGFBP7., PMID:38218180
Blockade of CD93 in pleural mesothelial cells fuels anti-lung tumor immune responses., PMID:38250037
CD93 maintains endothelial barrier function and limits metastatic dissemination., PMID:38441970
Group XIV C-type lectins: emerging targets in tumor angiogenesis., PMID:38468017
Effect of nonsteroidal anti-inflammatory drugs (aspirin and naproxen) on inflammation-associated proteomic profiles in mouse plasma and prostate during TMPRSS2-ERG (fusion)-driven prostate carcinogenesis., PMID:38506376
CD93 regulates breast cancer growth and vasculogenic mimicry through the PI3K/AKT/SP2 signaling pathway activated by integrin β1., PMID:38511888
Proteomics on human cerebral cavernous malformations reveals novel biomarkers in neurovascular dysfunction for the disease pathology., PMID:38537685
Unveiling the role of IL-17: Therapeutic insights and cardiovascular implications., PMID:38735805
Enrichment of Bioactive Lipids in Urinary Extracellular Vesicles and Evidence of Apoptosis in Kidneys of Hypertensive Diabetic Cathepsin B Knockout Mice after Streptozotocin Treatment., PMID:38791000
First Trimester Placental Biomarkers for Pregnancy Outcomes., PMID:38892323
Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity., PMID:38896451
Pathogen stimulations and immune cells synergistically affect the gene expression profile characteristics of porcine peripheral blood mononuclear cells., PMID:39054472
Identification of two key biomarkers CD93 and FGL2 associated with survival of acute myeloid leukaemia by weighted gene co-expression network analysis., PMID:39054581
Systematic Druggable Genome-Wide Mendelian Randomization Identifies Therapeutic Targets for Functional Outcome After Ischemic Stroke., PMID:39119979
IGFBP7 mediates oxLDL-induced human vascular endothelial cell injury by suppressing the expression of SIRT1., PMID:39170442
Clinicopathological association of CD93 expression in gastric adenocarcinoma., PMID:39190192
Lithium-induced apoptotic cell death is not accompanied by a noticeable inflammatory response in the kidney., PMID:39234304
Immune cells mediate the causal pathway linking circulating complements to cancer: A Mendelian randomization study., PMID:39352488
Exploring the hub Genes and Potential Mechanisms of Complement system-related Genes in Parkinson Disease: Based on Transcriptome Sequencing and Mendelian Randomization., PMID:39373800
Targeting CD93 on monocytes revitalizes antitumor immunity by enhancing the function and infiltration of CD8+ T cells., PMID:39448202
[Relationship of cerebrospinal fluid and serum levels of SIL-2R, eNOS, and CD93 with the progression and prognosis of viral encephalitis in children]., PMID:39467677
Interleukin-17D accelerates atherosclerosis through promoting endothelial cells ferroptosis via CD93/miR-181a-5p/SLC7A11 signaling., PMID:39510035
Immuno-PET Imaging of CD93 Expression with 64Cu-Radiolabeled NOTA-mCD93 ([64Cu]Cu-NOTA-mCD93) and Insulin-Like Growth Factor Binding Protein 7 ([64Cu]Cu-NOTA-IGFBP7)., PMID:39533706
CD93 aggravates cell proliferation, angiogenesis and immune escape in osteosarcoma through triggering the PI3K/AKT pathway., PMID:39542800
Avian pathogenic Escherichia coli alters complement gene expression in chicken erythrocytes., PMID:39757946
CD93 blockade promotes effector T-cell infiltration and facilitates adoptive cell therapy in solid tumors., PMID:39805660
Expression and prognostic significance of CD93 in blood vessels in colorectal cancer: an immunohistochemical analysis of 134 cases., PMID:39962383
Comprehensive analysis of CLEC family genes in gastric cancer prognosis immune response and treatment., PMID:39966377
Structural and antigen-binding surface definition of an anti-CD93 monoclonal antibody for the treatment of degenerative vascular eye diseases., PMID:40228767
For research use only. Not for human or drug use.
