Catalog No.
EHF64001
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Arg370
Predicted molecular weight
41.14 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P78324
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BIT, Signal-regulatory protein alpha-1, Brain Ig-like molecule with tyrosine-based activation motifs, MFR, SIRP, Sirp-alpha-1, Sirp-alpha-2, PTPNS1, SIRPA, SHP substrate 1, CD172 antigen-like family member A, Sirp-alpha-3, Inhibitory receptor SHPS-1, Signal-regulatory protein alpha-3, CD172a, Tyrosine-protein phosphatase non-receptor type substrate 1, MyD-1 antigen, Bit, SHPS-1, Macrophage fusion receptor, Signal-regulatory protein alpha-2, SHPS1, MYD1, p84
Modulatory Effects of the Recombinant Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike S1 Subunit Protein on the Phenotype of Camel Monocyte-Derived Macrophages., PMID:40136548
Newly Found Rat CD103 - Dendritic Cells Represent a Highly Immunogenic Subpopulation of Type-2 Conventional Dendritic Cells, Corresponding to Known Dendritic Cell Subsets in Mice and Humans., PMID:39754477
Expression of FcμR by bovine mononuclear blood leukocytes., PMID:39674305
Systemic and mammary inflammation and mammary gland development of Holstein dairy cows around dry-off and calving., PMID:39662814
PPARα agonist ameliorates cholestatic liver injury by regulating hepatic macrophage homeostasis., PMID:39647740
Establishment and characterization of an immortalized red river hog blood-derived macrophage cell line., PMID:39324137
Molecular changes in endometrium origin stromal cells during initiation of cardiomyogenic differentiation induced with Decitabine, Angiotensin II and TGF- β1., PMID:39043870
Phenotypic characterisation of bovine alveolar macrophages reveals two major subsets with differential expression of CD163., PMID:38951667
Effects of a humanized CD47 antibody and recombinant SIRPα proteins on triple negative breast carcinoma stem cells., PMID:38495618
Intratumoral PPT1-positive macrophages determine immunosuppressive contexture and immunotherapy response in hepatocellular carcinoma., PMID:37385725
A MD Simulation Prediction for Regulation of N-Terminal Modification on Binding of CD47 to CD172a in a Force-Dependent Manner., PMID:37241964
Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway., PMID:36912917
Characterization of the immune system of Ellegaard Göttingen Minipigs - An important large animal model in experimental medicine., PMID:36203585
Prevention of mastitis in multiparous dairy cows with a previous history of mastitis by oral feeding with probiotic Bacillus subtilis., PMID:36085592
Co-Expression of the B-Cell Key Transcription Factors Blimp-1 and IRF4 Identifies Plasma Cells in the Pig., PMID:35464468
Porcine Plasmacytoid Dendritic Cells Are Unique in Their Expression of a Functional NKp46 Receptor., PMID:35371050
SIRPα+ macrophages are increased in patients with FL who progress or relapse after frontline lenalidomide and rituximab., PMID:35359004
Flt3L, LIF, and IL-10 combination promotes the selective in vitro development of ESAMlow cDC2B from murine bone marrow., PMID:35357005
Characterisation of dendritic cell frequency and phenotype in bovine afferent lymph reveals kinetic changes in costimulatory molecule expression., PMID:34861459
IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses., PMID:34659203
Nicotinamide mononucleotide-elicited NAMPT signaling activation aggravated adjuvant-induced arthritis in rats by affecting peripheral immune cells differentiation., PMID:34130151
Myocardial hypoxic stress mediates functional cardiac extracellular vesicle release., PMID:34104945
Lactobacillus johnsonii activates porcine monocyte derived dendritic cells maturation to modulate Th cellular immune response., PMID:34029942
Early supplementation with Lactobacillus plantarum in liquid diet modulates intestinal innate immunity through toll-like receptor 4-mediated mitogen-activated protein kinase signaling pathways in young piglets challenged with Escherichia coli K88., PMID:33928383
The Isolation and Replication of African Swine Fever Virus in Primary Renal-Derived Swine Macrophages., PMID:33816588
Suppression of liver transplant rejection by anti-donor MHC antibodies via depletion of donor immunogenic dendritic cells., PMID:33258927
Development of Pig Conventional Dendritic Cells From Bone Marrow Hematopoietic Cells in vitro., PMID:33162975
Scald Injury-Induced T Cell Dysfunction Can Be Mitigated by Gr1+ Cell Depletion and Blockage of CD47/CD172a Signaling., PMID:32477354
Dromedary camel CD14high MHCIIhigh monocytes display inflammatory properties and are reduced in newborn camel calves., PMID:32070351
[Next generation of anti-immune checkpoints antibodies]., PMID:31903901
Theileria annulata transformation altered cell surface molecules expression and endocytic function of monocyte-derived dendritic cells., PMID:31899129
Checkpoint CD47 Function On Tumor Metastasis And Immune Therapy., PMID:31806995
Analysis of Swine Conventional Dendritic Cells, DEC205+CD172a+/-CADM1+, from Blood and Spleen in Response to PRRSV and PEDV., PMID:31683569
Equine herpesvirus 1 infection orchestrates the expression of chemokines in equine respiratory epithelial cells., PMID:31490114
Electroporation of a nanoparticle-associated DNA vaccine induces higher inflammation and immunity compared to its delivery with microneedle patches in pigs., PMID:31265882
Pattern of CD14, CD16, CD163 and CD172a expression on water buffalo (Bubalus bubalis) leukocytes., PMID:31084887
Impact of PRRSV strains of different in vivo virulence on the macrophage population of the thymus., PMID:31030838
How Adhesion Molecule Patterns Change While Neutrophils Traffic through the Lung during Inflammation., PMID:30944544
Immune cell populations residing in mesenteric adipose depots and mesenteric lymph nodes of lean dairy cows., PMID:30799109
Impact of uterine macrophage phenotype on placental retention in dairy cows., PMID:30695743
Recruitment of macrophages and bone marrow stem cells to regenerating liver promoted by sodium phthalhydrazide in mice., PMID:30537676
A subset of CD1c+ dendritic cells is increased in patients with tuberculosis and promotes Th17 cell polarization., PMID:30514502
Characterization of the Myeloid Cell Populations' Resident in the Porcine Palatine Tonsil., PMID:30158925
Molecular functions of SIRPα and its role in cancer., PMID:29930800
The Neuro-Immune-Regulators (NIREGs) Promote Tissue Resilience; a Vital Component of the Host's Defense Strategy against Neuroinflammation., PMID:29909495
Membrane fluctuations and acidosis regulate cooperative binding of 'marker of self' protein CD47 with the macrophage checkpoint receptor SIRPα., PMID:29777034
Phenotypic and functional analysis of bovine peripheral blood dendritic cells before parturition by a novel purification method., PMID:29708291
Influence of adipocyte size and adipose depot on the number of adipose tissue macrophages and the expression of adipokines in dairy cows at the end of pregnancy., PMID:29627241
Neonatal porcine blood derived dendritic cell subsets show activation after TLR2 or TLR9 stimulation., PMID:29555549
A new RelB-dependent CD117+ CD172a+ murine DC subset preferentially induces Th2 differentiation and supports airway hyperresponses in vivo., PMID:29485182
For research use only. Not for human or drug use.
