Catalog No.
YHC39801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln27-Ser220
Predicted molecular weight
24.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09326
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Signaling lymphocytic activation molecule 2, TCT.1, CD48 antigen, B-lymphocyte activation marker BLAST-1, BCM1, CD48, BLAST1, Leukocyte antigen MEM-102, SLAMF2, BCM1 surface antigen, SLAM family member 2
Mast cell modulation of immune responses to bacteria. PMID: 11292019
Assessment of NK Cell Activity Based on NK Cell-Specific Receptor Synergy in Peripheral Blood Mononuclear Cells and Whole Blood. PMID: 33143099
A ligand for human CD48 on epithelial cells. PMID: 9378979
Regulation of T lymphocyte function by glycosylphosphatidylinositol (GPI)-anchored proteins. PMID: 8054537
Hematopoiesis Remains Permissive to Bone Marrow Transplantation After Expansion of Progenitors and Resumption of Blood Cell Production. PMID: 34414177
Immune evasion by oncogenic proteins of acute myeloid leukemia. PMID: 24449212
CD48 monoclonal antibody K31 for bone marrow transplantation. PMID: 1438442
Influence of breast cancer on thymic function in mice. PMID: 12463739
2B4 (CD244) is a non-MHC binding receptor with multiple functions on natural killer cells and CD8+ T cells. PMID: 15607804
Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors. PMID: 16569764
Identification Hub Genes in Colorectal Cancer by Integrating Weighted Gene Co-Expression Network Analysis and Clinical Validation in vivo and vitro. PMID: 32426282
Analysis of cell-adhesion molecule interactions using surface plasmon resonance. PMID: 8725949
Inhibitory and activating receptors involved in immune surveillance by human NK and myeloid cells. PMID: 10577499
2B4: an NK cell activating receptor with unique specificity and signal transduction mechanism. PMID: 10658976
The structure and ligand interactions of CD2: implications for T-cell function. PMID: 8871350
sCD48 is anti-inflammatory in Staphylococcus aureus Enterotoxin B-induced eosinophilic inflammation. PMID: 26836239
Determination of the lifetime and force dependence of interactions of single bonds between surface-attached CD2 and CD48 adhesion molecules. PMID: 8986773
Parallels in T lymphocyte development between lpr and normal mice. PMID: 8167306
Receptors for unopsonized particles: the role of alveolar macrophage scavenger receptors. PMID: 11899233
Regulation of mast cell-mediated innate immunity during early response to bacterial infection. PMID: 11975423
NKG2D ligation relieves 2B4-mediated NK-cell self-tolerance in mice. PMID: 24610736
The dependence of the association rate of surface-attached adhesion molecules CD2 and CD48 on separation distance. PMID: 9091309
Dancing the immunological two-step. PMID: 10428718
Cell biology. Bacterial spelunkers. PMID: 10950716
Structural biology of the cell adhesion protein CD2: alternatively folded states and structure-function relation. PMID: 12369898
The association of the protein tyrosine kinases p56lck and p60fyn with the glycosyl phosphatidylinositol-anchored proteins Thy-1 and CD48 in rat thymocytes is dependent on the state of cellular activation. PMID: 8104794
Targeted disruption of the 2B4 gene in mice reveals an in vivo role of 2B4 (CD244) in the rejection of B16 melanoma cells. PMID: 15634901
Antitumour activity of a chimeric antibody against the leucocyte antigen CD48. PMID: 10630312
Homotypic cell to cell cross-talk among human natural killer cells reveals differential and overlapping roles of 2B4 and CD2. PMID: 20813844
Fab antibody fragment-functionalized liposomes for specific targeting of antigen-positive cells. PMID: 28939491
A critical role for CD48 antigen in regulating alloengraftment and lymphohematopoietic recovery after bone marrow transplantation. PMID: 9834253
Eosinophils interaction with mast cells: the allergic effector unit. PMID: 24986621
The human leucocyte antigen CD48 (MEM-102) is closely related to the activation marker Blast-1. PMID: 1999350
Stat5 deficiency decreases transcriptional heterogeneity and supports emergence of hematopoietic sub-populations. PMID: 28390194
Increased expression of CD48 on neutrophils activated in childhood patients with aplastic anemia. PMID: 7534499
Mechanism of induction of NK activation by 2B4 (CD244) via its cognate ligand. PMID: 20881194
Macrophages lift off surface-bound bacteria using a filopodium-lamellipodium hook-and-shovel mechanism. PMID: 24097079
Characterisation of the low affinity interaction between rat cell adhesion molecules CD2 and CD48 by analytical ultracentrifugation. PMID: 9188168
Functional capability of IL-15-Akt signaling in the denervated muscle. PMID: 23017227
The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells. PMID: 22693613
Enhanced murine CD4+ T cell responses induced by the CD2 ligand CD48. PMID: 9862369
COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1+ neutrophils and CD14+ monocytes. PMID: 34143756
Radiation-induced bystander effect in immune response. PMID: 15202863
Analysis of mutation in the rat Pig-a assay: II. Studies with bone marrow granulocytes. PMID: 30091248
Identification of a clonally expanding haematopoietic compartment in bone marrow. PMID: 23188081
Receptors and counterreceptors involved in NK-B cell interactions. PMID: 15778370
Further evidence for a gamma/delta T cell receptor-mediated TCT.1/CD48 recognition. PMID: 1655899
Clonal T cells of pure red-cell aplasia. PMID: 16044445
Infection mobilizes hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signaling. PMID: 24882704
For research use only. Not for human or drug use.
