Anti-NPrPSA Antibody (13D9)

Catalog No.

RGK29701

Description

Monoclonal antibodies 13D9 is specific for N-propionylated polysialic acid (NPrPSA),and 13D9 is protective against meningitis caused by group B meningococci and Escherichia coli capsular type K1 infection.

Species reactivity

group B meningococci,Escherichia coli capsular type K1

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

NPrPSA, N-propionylated polysialic acid, N-propionylated PSA

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

Blocking, ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

13D9

The antigen-binding site of an N-propionylated polysialic acid-specific antibody protective against group B meningococci is consistent with extended epitopes., PMID:23704298

N-Propionyl polysialic acid precursor enhances the susceptibility of multiple myeloma to antitumor effect of anti-NprPSA monoclonal antibody., PMID:23123647

Polysialic acid bioengineering of neuronal cells by N-acyl sialic acid precursor treatment., PMID:17172262

Activity and cross-reactivity of antibodies induced in mice by immunization with a group B meningococcal conjugate., PMID:11598089

N-Propionylated group B meningococcal polysaccharide mimics a unique bactericidal capsular epitope in group B Neisseria meningitidis., PMID:9166422

N-propionylated group B meningococcal polysaccharide mimics a unique epitope on group B Neisseria meningitidis., PMID:2435835

Document Download

Anti-NPrPSA Antibody (13D9).pdf