Catalog No.
YVV08801
Expression system
E. coli
Species
Human papillomavirus type 16
Protein length
Ser2-Leu505
Predicted molecular weight
84.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A0A3G2LCQ6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Major capsid protein L1, L1
Mutation Profile of HPV16 L1 and L2 Genes in Different Geographic Areas. PMID: 36680181
Anti-L1 antibody-bound HPV16 pseudovirus is degraded intracellularly via TRIM21/proteasomal pathway. PMID: 35619167
HPV16 L1 diversity and its potential impact on the vaccination-induced immunity. PMID: 32304786
Attenuated Salmonella carrying plasmid co-expressing HPV16 L1 and siRNA-E6 for cervical cancer therapy. PMID: 34635698
Correlation between cervical HPV DNA detection and HPV16 seroreactivity measured with L1-only and L1+L2 viral capsid antigens. PMID: 32510304
HPV16-L1-specific antibody response is associated with clinical remission of high-risk HPV-positive early dysplastic lesions. PMID: 25202103
High levels of HPV16-L1 antibody but not HPV16 DNA load or integration predict oropharyngeal patient outcome: The Papillophar study. PMID: 35199231
Correlation of HPV16 L1 capsid protein expression in cervical dysplasia with HPV16 DNA concentration, HPV16 E6*I mRNA and histologic outcome. PMID: 19697723
HPV16 E5 Mediates Resistance to PD-L1 Blockade and Can Be Targeted with Rimantadine in Head and Neck Cancer. PMID: 31848196
Controlled Hybrid-Assembly of HPV16/18 L1 Bi VLPs in Vitro. PMID: 27998118
Heterogeneous Nuclear Ribonucleoprotein C Proteins Interact with the Human Papillomavirus Type 16 (HPV16) Early 3'-Untranslated Region and Alleviate Suppression of HPV16 Late L1 mRNA Splicing. PMID: 25878250
Immunogenicity assessment of HPV16/18 vaccine using the glutathione S-transferase L1 multiplex serology assay. PMID: 25483632
HPV16 L2 improves HPV16 L1 gene delivery as an important approach for vaccine design against cervical cancer. PMID: 26925750
HPV16 L1 and L2 DNA methylation predicts high-grade cervical intraepithelial neoplasia in women with mildly abnormal cervical cytology. PMID: 23335178
Clinicopathological implications of human papilloma virus (HPV) L1 capsid protein immunoreactivity in HPV16-positive cervical cytology. PMID: 24396289
Identification of HPV16's E6 gene in suspected cases of cervical lesions and docking Study of its L1 protein with active components of Echinacea purpurae. PMID: 36032471
E2/E6 ratio and L1 immunoreactivity as biomarkers to determine HPV16-positive high-grade squamous intraepithelial lesions (CIN2 and 3) and cervical squamous cell carcinoma. PMID: 29400024
HPV16 Entry into Epithelial Cells: Running a Gauntlet. PMID: 34960729
The L1 major capsid protein of HPV16 differentially modulates APC trafficking according to the vaccination or natural infection context. PMID: 21061438
Effect of HPV16 L1 virus-like particles on the aggregation of non-functionalized gold nanoparticles. PMID: 28889068
Exploring the roles of HPV16 variants in head and neck squamous cell carcinoma: current challenges and opportunities. PMID: 34749746
Astaxanthin Prevents Human Papillomavirus L1 Protein Binding in Human Sperm Membranes. PMID: 30400141
Survival-related indicators ALOX12B and SPRR1A are associated with DNA damage repair and tumor microenvironment status in HPV 16-negative head and neck squamous cell carcinoma patients. PMID: 35768785
hnRNP L controls HPV16 RNA polyadenylation and splicing in an Akt kinase-dependent manner. PMID: 28934469
ISA101 and nivolumab for HPV-16+ cancer: updated clinical efficacy and immune correlates of response. PMID: 35193933
The papillomavirus major capsid protein L1. PMID: 23800545
Study results and related evidence do not support use of HPV16 L1 DRH1 antibodies as a cancer screening test. PMID: 33249381
Response to: "Study results and related evidence do not support use of HPV16 L1 DRH1 antibodies as a cancer screening test". PMID: 33254024
A colorimetric aptasensor for the simple and rapid detection of human papillomavirus type 16 L1 proteins. PMID: 33688885
Human papillomavirus L1 protein expressed in Escherichia coli self-assembles into virus-like particles that are highly immunogenic. PMID: 27107614
An Examination of HPV16 Natural Immunity in Men Who Have Sex with Men (MSM) in the HPV in Men (HIM) Study. PMID: 29475967
The study of immunogenicity of the antigenic protein of high risk oncogenic type of the human papillomavirus HPV16 L1 produced in the plant expression system on the base of transgenic tomato. PMID: 28726109
Mapping the B cell epitopes within the major capsid protein L1 of human papillomavirus type 16. PMID: 29959021
Humoral Response to HPV16 Proteins in Persons with Anal High-Grade Squamous Intraepithelial Lesion or Anal Cancer. PMID: 32883662
Genetic Variability in the E6, E7, and L1 Genes of Human Papillomavirus Types 16 and 18 among Women in Saudi Arabia. PMID: 36680149
Comparison of multiplex-serology and ELISA based methods in detecting HPV16 L1 antibody responses in paired saliva and serum samples of healthy men. PMID: 31004663
IgG and IgM responses to human papillomavirus L1 virus-like particle as a function of dosing schedule and vaccine formulation. PMID: 31452045
Characterization of major capsid protein (L1) variants of Human papillomavirus type 16 by cervical neoplastic status in Indian women: Phylogenetic and functional analysis. PMID: 31944308
HPV-16 RNA processing. PMID: 18508629
Genetic signatures for lineage/sublineage classification of HPV16, 18, 52 and 58 variants. PMID: 33238224
Effect of alternative aluminum adjuvants on the absorption and immunogenicity of HPV16 L1 VLPs in mice. PMID: 17581283
Human papillomavirus 16 L1 gene methylation as a potential biomarker for predicting anal intraepithelial neoplasia in men who have sex with men (MSM). PMID: 34469465
Methylation of CpG 5962 in L1 of the human papillomavirus 16 genome as a potential predictive marker for viral persistence: A prospective large cohort study using cervical swab samples. PMID: 31856411
Situation of HPV16 E2 gene status during radiotherapy treatment of cervical carcinoma. PMID: 24761916
Enhanced expression of soluble human papillomavirus L1 through coexpression of molecular chaperonin in Escherichia coli. PMID: 26732286
Sex differences in HPV immunity among adults without cancer. PMID: 30650013
Displaying 31RG-1 peptide on the surface of HPV16 L1 by use of a human papillomavirus chimeric virus-like particle induces cross-neutralizing antibody responses in mice. PMID: 29683766
Identification of heterogenous nuclear ribonucleoproteins (hnRNPs) and serine- and arginine-rich (SR) proteins that induce human papillomavirus type 16 late gene expression and alter L1 mRNA splicing. PMID: 34860285
Prevalence and distribution of human papillomavirus (HPV) in Luoyang city of Henan province during 2015-2021 and the genetic variability of HPV16 and 52. PMID: 35246180
The DNA damage response activates HPV16 late gene expression at the level of RNA processing. PMID: 29596642
Critical Residues Involved in the Coassembly of L1 and L2 Capsid Proteins of Human Papillomavirus 16. PMID: 36815785
VLP production in Leishmania tarentolae: A novel expression system for purification and assembly of HPV16 L1. PMID: 26304732
Methylation of HPV16 genome CpG sites is associated with cervix precancer and cancer. PMID: 21306759
Post-treatment human papillomavirus antibody kinetics in cervical cancer patients. PMID: 30955486
Comparative Evaluation of Human Papillomavirus Type 16 L1 Protein Expressed in Plasmid- and Baculovirus-Based Systems in Insect Cells. PMID: 32621447
Development of an IP-Free Biotechnology Platform for Constitutive Production of HPV16 L1 Capsid Protein Using the Pichia pastoris PGK1 Promoter. PMID: 26090426
HPV16 antibodies as risk factors for oropharyngeal cancer and their association with tumor HPV and smoking status. PMID: 25957822
Non-Functionalized Gold Nanoparticles Inhibit Human Papillomavirus (HPV) Infection. PMID: 35886898
The HPV transcriptome in HPV16 positive cell lines. PMID: 21439369
For research use only. Not for human or drug use.
