Catalog No.
PHA89801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human GDF9 (Gly320-Arg454).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Growth/differentiation factor 9,GDF-9,GDF9
Purification
Purified by antigen affinity column.
Accession
O60383
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Roles of GDF9 and BMP15 in equine follicular development: in vivo content and in vitro effects of IGF1 and cortisol on granulosa cells., PMID:40289073
Isolation of female germline stem cells from neonatal piglet ovarian tissue and differentiation into oocyte-like cells., PMID:36525858
Enhanced method to select human oogonial stem cells for fertility research., PMID:34415395
New insights into the GDF9-Hedgehog-GLI signaling pathway in human ovaries: from fetus to postmenopause., PMID:33772413
Activation-induced cytidine deaminase is a possible regulator of cross-talk between oocytes and granulosa cells through GDF-9 and SCF feedback system., PMID:33589683
Eukaryotic expression, Co-IP and MS identify BMPR-1B protein-protein interaction network., PMID:32471519
Influence of growth differentiation factor 9 and bone morphogenetic protein 15 on in vitro maturation of canine oocytes., PMID:30388311
Embryonic poly(A)-binding protein is differently expressed and interacts with the messenger RNAs in the mouse oocytes and early embryos., PMID:30302808
Enrichment of Female Germline Stem Cells from Mouse Ovaries Using the Differential Adhesion Method., PMID:29723864
Effect of human ZP3 monoclonal antibody on expression of GDF-9 and number of theca cells in ovary of mice (Mus musculus)., PMID:31435327
In vitro differentiation of human oocyte-like cells from oogonial stem cells: single-cell isolation and molecular characterization., PMID:29304224
Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling., PMID:29221447
Molecular forms of ruminant BMP15 and GDF9 and putative interactions with receptors., PMID:28733348
Differential expression of GDF-9 and BMP- 15 during follicular development in canine ovaries evaluated by flow cytometry., PMID:26876149
Immune-mediated destruction of ovarian follicles associated with the presence of HSP90 antibodies., PMID:25653208
Beneficial effects of melatonin on bovine oocytes maturation: a mechanistic approach., PMID:25070516
Female reproductive aging is master-planned at the level of ovary., PMID:24788203
Human amniotic fluid stem cells have a potential to recover ovarian function in mice with chemotherapy-induced sterility., PMID:24006896
Expression of growth differentiation factor 9 (GDF-9) during in vitro maturation in canine oocytes., PMID:23849650
Overexpression of Uromodulin-like1 accelerates follicle depletion and subsequent ovarian degeneration., PMID:23190605
Effects of species differences on oocyte regulation of granulosa cell function., PMID:22967842
Regulatory role of kit ligand-c-kit interaction and oocyte factors in steroidogenesis by rat granulosa cells., PMID:22366471
Active immunization against the proregions of GDF9 or BMP15 alters ovulation rate and litter size in mice., PMID:22106408
Inhibition of oocyte growth factors in vivo modulates ovarian folliculogenesis in neonatal and immature mice., PMID:20007639
Effects of active immunization against growth differentiation factor 9 and/or bone morphogenetic protein 15 on ovarian function in cattle., PMID:19439562
The proregion of mouse BMP15 regulates the cooperative interactions of BMP15 and GDF9., PMID:18633140
Fibroblast growth factor 7 stimulates in vitro growth of oocytes originating from bovine early antral follicles., PMID:18386286
Characterization of the post-translational modification of recombinant human BMP-15 mature protein., PMID:18227435
The cooperative effect of growth and differentiation factor-9 and bone morphogenetic protein (BMP)-15 on granulosa cell function is modulated primarily through BMP receptor II., PMID:18063682
Inhibition of premature oocyte maturation: a role for bone morphogenetic protein 15 in zebrafish ovarian follicles., PMID:17656459
Induction of oocyte-like cells from mouse embryonic stem cells by co-culture with ovarian granulosa cells., PMID:17490416
The role of growth differentiation factor-9 (GDF-9) and its analog, GDF-9b/BMP-15, in human breast cancer., PMID:17453295
The effects of immunizing sheep with different BMP15 or GDF9 peptide sequences on ovarian follicular activity and ovulation rate., PMID:17093201
Characterization of NOBOX DNA binding specificity and its regulation of Gdf9 and Pou5f1 promoters., PMID:16997917
A unique preovulatory expression pattern plays a key role in the physiological functions of BMP-15 in the mouse., PMID:16818886
Cell type- and stage-specific changes in HOXA7 protein expression in human ovarian folliculogenesis: possible role of GDF-9., PMID:16466395
[Protective effect of zuogui pill on ovarian autoimmune injury]., PMID:16313118
Oocytes prevent cumulus cell apoptosis by maintaining a morphogenic paracrine gradient of bone morphogenetic proteins., PMID:16263764
Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulosa cell function., PMID:15798022
Role of oocyte-secreted growth differentiation factor 9 in the regulation of mouse cumulus expansion., PMID:15761035
Expression and function of growth differentiation factor-9 in an oviparous species, Gallus domesticus., PMID:15625233
Immunoneutralization of growth differentiation factor 9 reveals it partially accounts for mouse oocyte mitogenic activity., PMID:15128595
Pregnancy-associated plasma protein-a production in rat granulosa cells: stimulation by follicle-stimulating hormone and inhibition by the oocyte-derived bone morphogenetic protein-15., PMID:15087430
Evaluation of members of the TGFbeta superfamily as candidates for the oocyte factors that control mouse cumulus expansion and steroidogenesis., PMID:14635927
Growth differentiation factor-9 and stem cell factor promote primordial follicle formation in the hamster: modulation by follicle-stimulating hormone., PMID:14585807
Growth differentiation factor-9 induces Smad2 activation and inhibin B production in cultured human granulosa-luteal cells., PMID:12574210
Growth differentiation factor-9 stimulates inhibin production and activates Smad2 in cultured rat granulosa cells., PMID:12488343
Growth differentiation factor 9 and bone morphogenetic protein 15 are essential for ovarian follicular development in sheep., PMID:12444053
Bone morphogenetic protein receptor type II is a receptor for growth differentiation factor-9., PMID:12135884
A negative feedback system between oocyte bone morphogenetic protein 15 and granulosa cell kit ligand: its role in regulating granulosa cell mitosis., PMID:12048244