Catalog No.
PHA82501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CXCL13/BCA-1/BLC (Val23-Arg94).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:2000-1:8000 |
Target
SCYB13,BLC,CXCL13,B cell-attracting chemokine 1,B lymphocyte chemoattractant,Small-inducible cytokine B13,CXC chemokine BLC,Angie,C-X-C motif chemokine 13,BCA-1,BCA1
Purification
Purified by antigen affinity column.
Accession
O43927
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Serum Proteomics Distinguish Subtypes of NMO Spectrum Disorder and MOG Antibody-Associated Disease and Highlight Effects of B-Cell Depletion., PMID:38885457
Neoadjuvant sintilimab plus chemotherapy in EGFR-mutant NSCLC: Phase 2 trial interim results (NEOTIDE/CTONG2104)., PMID:38897205
Tumor-Immune Signatures of Treatment Resistance to Brentuximab Vedotin with Ipilimumab and/or Nivolumab in Hodgkin Lymphoma., PMID:38934093
Antibody responses to immunoevasion proteins BBK32 and OspE constitute part of the serological footprint in neuroborreliosis but are insufficient to prevent the disease., PMID:39007994
Cerebrospinal Fluid Cytokine and Chemokine Profiles in Central Nervous System Sarcoidosis: Diagnostic and Immunopathologic Insights., PMID:39031103
Correlation of cTfh cells and memory B cells with AMR after renal transplantation., PMID:39038741
Anti-mCD20 in combination with α-mCXCL13 monoclonal antibody inhibits anti-FVIII antibody development in hemophilia A mice., PMID:39067397
T peripheral helper (Tph) cells, a marker of immune activation in cancer and autoimmune disorders., PMID:39067677
The active form of vitamin D (calcitriol) promotes CXCR5 expression during follicular helper T cell differentiation., PMID:39101520
Dissecting the Distinct Tumor Microenvironments of HRD and HRP Ovarian Cancer: Implications for Targeted Therapies to Overcome PARPi Resistance in HRD Tumors and Refractoriness in HRP Tumors., PMID:39136172
Effect of Follicular T Helper and T Helper 17 Cells-Related Molecules on Disease Severity in Patients with Myasthenia Gravis., PMID:39168115
CCL9/CCR1 axis-driven chemotactic nanovesicles for attenuating metastasis of SMAD4-deficient colorectal cancer by trapping TGF-β., PMID:39220887
Single-cell and spatial transcriptome analyses reveal tertiary lymphoid structures linked to tumour progression and immunotherapy response in nasopharyngeal carcinoma., PMID:39231979
Polymorphisms in genes involved in regulating follicular helper T cell differentiation predict de novo donor-specific antibody formation after liver transplantation., PMID:39255558
Clinical and laboratory characteristics during a 1-year follow-up in European Lyme neuroborreliosis: A prospective cohort study., PMID:39297748
Sphingosine-1-phosphate receptor type 4 is critically involved in the regulation of peritoneal B-1 cell trafficking and distribution in vivo., PMID:39344245
Occurrence and role of Tph cells in various renal diseases., PMID:39390361
Spatial Dynamics of T- and B-Cell Responses Predicts Clinical Outcome of Resectable and Unresectable Hepatocellular Carcinoma., PMID:39417698
Cladribine tablets in relapsing-remitting multiple sclerosis preferentially target B-cells., PMID:39428028
CXCL13 promotes broad immune responses induced by circular RNA vaccines., PMID:39436660
CXCL13/CXCR5 axis facilitates TFH expansion and correlates with disease severity in adults with immune thrombocytopenia., PMID:39454362
High serum levels of CXCL13 predict lower response to csDMARDs in both ACPA-positive and ACPA-negative early rheumatoid arthritis., PMID:39468732
Chemokine CXCL13 facilitates anti-FVIII inhibitory antibody development in hemophilia A patients and murine models., PMID:39471695
Sex-Based Differences in Thyroid Plasma B Cell Infiltration: Implications for Autoimmune Disease Susceptibility., PMID:39487734
The role of polyreactive memory B cells in systemic lupus erythematosus., PMID:39514642
Tumor-specific antibodies elicited by engineered bacteria promote bladder cancer immunotherapy., PMID:39554157
Skin immune-mesenchymal interplay within tertiary lymphoid structures promotes autoimmune pathogenesis in hidradenitis suppurativa., PMID:39662091
Cerebrospinal Fluid Cytology in Lyme Neuroborreliosis Revisited-Role of Neutrophilic Granulocytes: A Retrospective Single-Center Study., PMID:39685862
Tertiary Lymphoid Structures are Linked to Enhanced Antitumor Immunity and Better Prognosis in Muscle-Invasive Bladder Cancer., PMID:39739621
CXCL13 levels in cerebrospinal fluid in relapsing-remitting multiple sclerosis: The role of Borrelia in neuroinfections., PMID:39792446
Dynamic analysis of intrahepatic T cells reveals a unique group of restorative Cxcr3+ tissue-resident CD4 T cells in acute liver injury., PMID:39828240
Pearls & Oy-sters: Recurrent Lyme Neuroborreliosis With Seroreversion in a Patient With Multiple Sclerosis on a B-Cell Depleting Therapy., PMID:39836939
CSF cytokine, chemokine and injury biomarker profile of glial fibrillary acidic protein (GFAP) autoimmunity., PMID:39869499
Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept., PMID:39925810
Single cell immunoprofile of synovial fluid in rheumatoid arthritis with TNF/JAK inhibitor treatment., PMID:40038288
Tissue-resident peripheral helper T cells foster hepatocellular carcinoma immune evasion by promoting regulatory B-cell expansion., PMID:40066780
Single-cell RNA-sequencing reveals cellular heterogeneity and immune microenvironment characteristics between ocular adnexal mucosa-associated lymphoid lymphoma and IgG4-related ophthalmic disease., PMID:40078987
Diffuse large B cell lymphoma in rheumatoid arthritis patients is associated with elevated B-cell driving factors including CXCL13., PMID:40118130
Distinct type 1 immune networks underlie the severity of restrictive lung disease after COVID-19., PMID:40140496
LTK deficiency induces macrophage M2 polarization and ameliorates Sjogren's syndrome by reducing chemokine CXCL13., PMID:40154092
Modulating IL-21-driven B cell responses in idiopathic inflammatory myopathies via inhibition of the JAK/STAT pathway., PMID:40170058
Prediction, prevention, and precision treatment of immune checkpoint inhibitor neurological toxicity using autoantibodies, cytokines, and microbiota., PMID:40181971
Plasma Exchange vs. Immunoadsorption: Effects on Immunological Markers and Predictive Value in Steroid-Refractory MS Attacks., PMID:40292037
Efficacy, safety and single-cell analysis of neoadjuvant immunochemotherapy in locally advanced oral squamous cell carcinoma: a phase II trial., PMID:40295492
Tph cells are expanded in IgA vasculitis nephritis., PMID:40315784
CXCL13 suppresses liver regeneration through the negative regulation of HGF signaling., PMID:40325003
Prognostic Factors of Proteinuria Remission in Primary Membranous Nephropathy., PMID:40363910
CXCL13 and CCL21 Induce Tertiary Lymphoid Structures and Enhance the Efficacy of Immunotherapy for Melanoma., PMID:40393449
High expression of CXCL13 predicts a favorable response to immunotherapy by upregulating CXCR5+CD8+ T-cell infiltration in gastric cancer., PMID:40406143
Increased Fascin1 and Pak1 Expressions Enhance Age-Associated B-Cell Actin Cytoskeleton Remodeling and Motility., PMID:40500987
For research use only. Not for human or drug use.
