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Anti-TOR1A Polyclonal Antibody

Catalog #:   PHA26101 Specific References (25) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: O14656
Overview

Catalog No.

PHA26101

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human TOR1A (Val33-Ser250).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Torsin-1A,TOR1A,Torsin family 1 member A,DQ2,Dystonia 1 protein,TORA,TA,Torsin ATPase-1A,DYT1

Purification

Purified by antigen affinity column.

Accession

O14656

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with TOR1A antibody (PHA26101) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 27 kDa
    Observed MW: 27 kDa
References

A2A Receptor Dysregulation in Dystonia DYT1 Knock-Out Mice., PMID:33799994

Dystonia: Sparse Synapses for D2 Receptors in Striatum of a DYT1 Knock-out Mouse Model., PMID:32041188

The possible link between coeliac and Kawasaki diseases in Brazil: a cross-sectional study., PMID:29444780

Phosphodiesterase-10A Inverse Changes in Striatopallidal and Striatoentopeduncular Pathways of a Transgenic Mouse Model of DYT1 Dystonia., PMID:28115486

Dystonia type 6 gene product Thap1: identification of a 50 kDa DNA-binding species in neuronal nuclear fractions., PMID:25231164

Dystonia-associated protein torsinA is not detectable at the nerve terminals of central neurons., PMID:24025868

Allelic Imbalance in TOR1A mRNA Expression in Manifesting and Non-Manifesting Carriers of the GAG-Deletion., PMID:22988486

Transglutaminase 2-targeted autoantibodies in celiac disease: Pathogenetic players in addition to diagnostic tools?, PMID:20547248

Transient expression of human TorsinA enhances secretion of two functionally distinct proteins in cultured Chinese hamster ovary (CHO) cells., PMID:19845036

The dystonia-associated protein torsinA modulates synaptic vesicle recycling., PMID:18167355

Stiff child syndrome with mutation of DYT1 gene., PMID:16682692

Silencing primary dystonia: lentiviral-mediated RNA interference therapy for DYT1 dystonia., PMID:16280588

Stiff child syndrome with mutation of DYT1 gene., PMID:16275837

Torsin-mediated protection from cellular stress in the dopaminergic neurons of Caenorhabditis elegans., PMID:15829632

Mutant torsinA, which causes early-onset primary torsion dystonia, is redistributed to membranous structures enriched in vesicular monoamine transporter in cultured human SH-SY5Y cells., PMID:15593317

TorsinB--perinuclear location and association with torsinA., PMID:15147511

TorsinA immunoreactivity in inclusion bodies in trinucleotide repeat diseases., PMID:14502672

Distribution and ultrastructural localization of torsinA immunoreactivity in the human brain., PMID:12965225

Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins., PMID:12554684

Immunocytochemical characterization of torsin proteins in mouse brain., PMID:11730696

A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study., PMID:11438481

Cellular distribution of torsin A and torsin B in normal human brain., PMID:11405807

Distribution and immunohistochemical characterization of torsinA immunoreactivity in rat brain., PMID:11334819

Mutant torsinA, responsible for early-onset torsion dystonia, forms membrane inclusions in cultured neural cells., PMID:10814722

Immunohistochemical localization and distribution of torsinA in normal human and rat brain., PMID:10640617

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-TOR1A Polyclonal Antibody [PHA26101]
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