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Anti-Human IL4 Antibody (8D4-8)

Catalog #:   RHC13501 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: ELISA, FCM, IHC, IP, Neutralization
Accession: P05112
Overview

Catalog No.

RHC13501

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Binetrakin, B-cell stimulatory factor 1, Pitrakinra, Lymphocyte stimulatory factor 1, IL-4, BSF-1, IL4, Interleukin-4

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P05112

Applications

ELISA, FCM, IHC, IP, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

8D4-8

Data Image
  • Flow-cytometry
    Flow-cytometry using anti-human IL4 antibody.IL4 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human IL4 antibody monoclonal antibody (Catalog # RHC13501 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # PMB96441) and cells analysed on a NovoCyte Flow Cytometer.
References

Oral administration of Lactiplantibacillus plantarum GKK1 ameliorates atopic dermatitis in a mouse model., PMID:40529585

[Research on the inhibitory effects of evodiamine on activated T cell proliferation]., PMID:40525340

Decreased pathogenicity of triple-mutant of Aeromonas hydrophila flgK, flgL, flgE suggests its potential as a live attenuated vaccine for Carassius auratus., PMID:40516799

The Immunology of Alpha-Gal Syndrome: History, Tick Bites, IgE, and Delayed Anaphylaxis to Mammalian Meat., PMID:40515672

A Promising Approach to Control Carbapenem-Resistant Acinetobacter baumannii: Investigating Immune Pathways Through rFilF Immunization., PMID:40513999

The dichotomous impacts of Semaphorin3E deficiency on exacerbating airway hyperresponsiveness, remodelling, and inflammation in type-2 low and type-2 high asthma models., PMID:40512736

Interleukin-4 and -13 Gene Expression Profiles in Immune-Related Bullous Pemphigoid Indicate Efficacy of IL-4/IL-13 Inhibitors., PMID:40507326

Improved protection against H9N2 avian influenza virus challenge in chickens by the presence of LTB adjuvant on the 3M2e-NP nanoparticle vaccine delivered by sifA deficient Salmonella., PMID:40505226

Dupilumab treatment has no effect on the nasal microbiome in patients with NSAID-exacerbated respiratory disease: a longitudinal pilot study., PMID:40503236

Effects of Rhodobacter sphaeroides protein on growth performance, nutrient digestibility, rumen fermentation, and serum metabolites in dairy calves during the pre- and postweaning periods., PMID:40499903

Selected cytokine and chemokine concentrations in equine autologous conditioned serum are similar under defined and practically relevant storage conditions., PMID:40496923

[Application and research progress of anti-IL-4α monoclonal antibody dupilumab in the treatment of type 2 asthma]., PMID:40491151

IL-18 favors Th2 responses in sporotrichosis caused by Sporothrix globosa, prolonging the course of the disease., PMID:40489556

Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis., PMID:40484710

Development of an oral gut-targeted rabies virus-like particles (RVLPs) vaccine with mucosal immune adjuvant LTB via delivering of localized-release microparticles., PMID:40476513

Selective sweep analysis reveals candidate genes related to immunity in Licha black pig., PMID:40473060

Protective Effect of Melissa officinalis (Lemon Balm) Extract on Cytokine Levels and Oxidative Stress in Ovalbumin Induced Lung Toxicity in Rats., PMID:40470741

Inhibition of IL-4Rα reduces CCL26 in bronchial epithelial cells from COPD patients., PMID:40470156

Humoral and cellular immune responses in cattle upon Clostridium chauvoei vaccination and challenge., PMID:40463373

Suppression of Il5 and Il13 Gene Expression by Synthetic siRNA Molecules Reduces Nasal Hyperreactivity and Inflammation in a Murine Model of Allergic Rhinitis., PMID:40451198

Fusion with CTB enhances the immunogenicity and protective efficacy of MIC2 subunit vaccine against Eimeria tenella., PMID:40449102

Differences in Aqueous Humor Cytokine Concentrations According to the Presence of Posterior Subcapsular Cataract: A Prospective Case-Control Study., PMID:40441712

How to Adjust Asthma Management Once Asthma Is Controlled on Long-Term Biologic Therapy., PMID:40436142

PRRSV GP4 subunit vaccine combined with adenovirus heterologous prime-boost immunization strategy induced a significant immune response in mice., PMID:40426193

Antiallergic activities of polysaccharides derived from Coptis chinensis., PMID:40425117

Immunogenicity evaluation of a recombinant pseudorabies virus co-expressing PCV2 and PCV3 capsid proteins in mice and piglets., PMID:40424702

[Protective аction of ginseng root extract on myofibril apoptosis and immune response in rats after exhausting physical exercise. Part II. Effect of ginseng root extract on immunity and regulation of energy metabolism]., PMID:40418135

The Combination of TLR4 and TLR9 Agonists with Self-Amplifying RNA Lipid Nanoparticles Leads to a More Powerful Immune Response Against SARS-CoV-2., PMID:40401447

Development of tolerogenic casein encapsulated quercetin and curcumin nanoparticles to mitigate cow milk allergic responses., PMID:40398766

Comparison of Different Methods of Constructing a Celiac Disease Model in BALB/c Mice., PMID:40395135

Systemic secukinumab treatment in patients with ankylosing spondylitis: the relationship between systemic and tear proinflammatory cytokines and ocular surface findings-a pilot study., PMID:40394377

Acremonium terricola culture supplementation in the diet of pregnant and lactating Ewes can improve the production performance of Ewes and lambs by regulating maternal metabolism and antibody delivery., PMID:40389975

Lymphocyte Subsets in Covid-19 Saudi Patients: Infection Caused Significant Reduction in Peripheral Blood Lymphocyte Subset., PMID:40387754

Immune efficacy of oprH chitosan nanoparticle DNA vaccine against Pseudomonas aeruginosa., PMID:40386097

Immunogenicity Evaluation of a SARS-CoV-2 BA.2 Subunit Vaccine Formulated with CpG 1826 plus alum Dual Adjuvant., PMID:40383947

Development and validation of a multiple myeloma diagnostic model based on systemic lupus erythematosus-associated genes and identification of specific genes., PMID:40382732

Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection., PMID:40378045

Dupilumab for the Treatment of Cutaneous Immune-Related Adverse Events: A Systematic Review., PMID:40375468

Association of STAT6 gene polymorphism with atopic asthma among Yemeni children in Sana'a city, Yemen., PMID:40375219

T2 cytokine-driven alarmin and antiviral responses in asthma: insights into immune modulation and the role of IL-4Rα targeting., PMID:40370530

Mycosis fungoides and IL-4/13 inhibitors: what is known and unmet needs., PMID:40369852

Сomprehensive approach to comparative characteristics of clinical and laboratory parameters of the study in children - in 6 months after Covid-19 treatment and 6 months after Covid-19 vaccination., PMID:40367469

Repeated exposure to 31 kDa protein fraction from the salivary gland of Aedes aegypti modulate humoral and cellular immune response in mouse model., PMID:40366975

Intranasal Immunotherapy with Allergen-Loaded Extracellular Vesicles from Mast Cells Alleviates Allergic Asthma Inflammation in a Murine Model., PMID:40366524

A Pathogen-Mimicking Monkeypox Virus Nanovaccine Inspired by Assembly of Viral Antigens with β-Glucan and Dendrimer., PMID:40366370

Cutaneous Adverse Events Following Nemolizumab Administration: A Review., PMID:40364058

Unveiling the immune and vitamin profiles of blood: the potential biomarkers for alopecia areata., PMID:40352276

Blocking of IL-4/IL-13 Signalling With Dupilumab Results in Restoration of Serum and Cutaneous Abnormalities in Netherton Syndrome., PMID:40344324

PROFILES FOR SOME KEY CYTOKINES AND AUTO-ANTIBODIES IN LATENT TOXOPLASMOSIS IN ABORTED WOMEN., PMID:40335055

Structural characterization and immune activity evaluation of polysaccharide purified from Viola phillipica., PMID:40334829

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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Anti-Human IL4 Antibody (8D4-8) [RHC13501]
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