Catalog No.
PHA04001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CCL24/Eotaxin-2/MPIF-2 (Val27-Cys119).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000 |
Target
MPIF2,Eosinophil chemotactic protein 2,Small-inducible cytokine A24,CCL24,Eotaxin-2,SCYA24,MPIF-2,Myeloid progenitor inhibitory factor 2,CK-beta-6,C-C motif chemokine 24
Purification
Purified by antigen affinity column.
Accession
O00175
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Oxidized LDL activated eosinophil polarize macrophage phenotype from M2 to M1 through activation of CD36 scavenger receptor., PMID:28623741
Human lactoferrin induces asthmatic symptoms in NC/Nga mice., PMID:28774951
Commensal microbiota maintains alveolar macrophages with a low level of CCL24 production to generate anti-metastatic tumor activity., PMID:28785009
Interleukin-33 promotes the inflammatory reaction in chronic rhinosinusitis with nasal polyps by NF-κB signaling pathway., PMID:29131267
Novel mediators of statin effects on plaque in HIV: a proteomics approach., PMID:29369166
Extensive serum biomarker analysis in patients with nasopharyngeal carcinoma., PMID:29759660
Mesenchymal Stromal Cell (MSC)-Derived Combination of CXCL5 and Anti-CCL24 Is Synergistic and Superior to MSC and Cyclosporine for the Treatment of Graft-versus-Host Disease., PMID:29883796
Aggregates of IVIG or Avastin, but not HSA, modify the response to model innate immune response modulating impurities., PMID:30065306
Sputum Antineutrophil Cytoplasmic Antibodies in Serum Antineutrophil Cytoplasmic Antibody-Negative Eosinophilic Granulomatosis with Polyangiitis., PMID:30179583
A synthetic glycosaminoglycan reduces sinonasal inflammation in a murine model of chronic rhinosinusitis., PMID:30252910
Eosinophils Mediate Basophil-Dependent Allergic Skin Inflammation in Mice., PMID:30910757
The Innate Immune Protein S100A9 Protects from T-Helper Cell Type 2-mediated Allergic Airway Inflammation., PMID:30943376
Blockade of CCL24 with a monoclonal antibody ameliorates experimental dermal and pulmonary fibrosis., PMID:31129606
Allergic rhinitis is associated with complex alterations in high-density lipoprotein composition and function., PMID:31185305
Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner., PMID:31285764
Eosinophil extracellular traps activate type 2 innate lymphoid cells through stimulating airway epithelium in severe asthma., PMID:31330043
IgG4 Related Autoimmune Pancreatitis: An Overview and the Emerging Role of Serum Eotaxin as a Potential Treatment Target., PMID:31542909
A blocking monoclonal antibody to CCL24 alleviates liver fibrosis and inflammation in experimental models of liver damage., PMID:32039405
Blocking the autocrine regulatory loop of Gankyrin/STAT3/CCL24/CCR3 impairs the progression and pazopanib resistance of clear cell renal cell carcinoma., PMID:32051393
Differential Gene Expression of Lymphocytes Stimulated with Rhinovirus A and C in Children with Asthma., PMID:32142615
Biologics or immunotherapeutics for asthma?, PMID:32275962
Possible Mechanisms of Eosinophil Accumulation in Eosinophilic Pneumonia., PMID:32326200
Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae., PMID:32394439
Increased CCL24 and CXCL7 levels in the cerebrospinal fluid of patients with neurosyphilis., PMID:32419252
Increased serum CCL26 level is a potential biomarker for the effectiveness of anti-PD1 antibodies in patients with advanced melanoma., PMID:32658051
Enhanced Type 2 Immune Reactions by Increased IL-22/IL-22Ra1 Signaling in Chronic Rhinosinusitis With Nasal Polyps., PMID:32935490
Non-invasive Embryo Assessment: Altered Individual Protein Profile in Spent Culture Media from Embryos Transferred at Day 5., PMID:33151525
IL-1α antibody inhibits dose-dependent exacerbation of eosinophilic inflammation by crude house-dust-mite antigen in the conjunctiva of an atopic keratoconjunctivitis mouse model., PMID:33428487
Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves' Disease., PMID:33912135
Study effect of probiotics and prebiotics on treatment of OVA-LPS-induced of allergic asthma inflammation and pneumonia by regulating the TLR4/NF-kB signaling pathway., PMID:35296330
Functional IKK/NF-κB signaling in pancreatic stellate cells is essential to prevent autoimmune pancreatitis., PMID:35624133
CCL24/CCR3 axis plays a central role in angiotensin II-induced heart failure by stimulating M2 macrophage polarization and fibroblast activation., PMID:36131165
Cytokines/chemokines and soluble immune checkpoint molecules in anti-GABAB receptor encephalitis., PMID:36270252
Immunomodulatory effects of β-defensin 2 on macrophages induced immuno-upregulation and their antitumor function in breast cancer., PMID:36324077
CCL24, CXCL9 and CXCL10 are increased in synovial fluid in patients with juvenile idiopathic arthritis requiring advanced treatment., PMID:36342195
Eotaxin-2 and eotaxin-3 in malaria exposure and pregnancy., PMID:36380370
Biomaterials-based immunomodulation enhances survival of murine vascularized composite allografts., PMID:37129566
CD200R signaling contributes to unfavorable tumor microenvironment through regulating production of chemokines by tumor-associated myeloid cells., PMID:37275530
CCL24 regulates biliary inflammation and fibrosis in primary sclerosing cholangitis., PMID:37345655
The Role of CCL24 in Systemic Sclerosis., PMID:37555717
The Eotaxin-1/CCR3 Axis and Matrix Metalloproteinase-9 Are Critical in Anti-NC16A IgE-Induced Bullous Pemphigoid., PMID:37672029
The Role of CCL24 in Primary Sclerosing Cholangitis: Bridging Patient Serum Proteomics to Preclinical Data., PMID:38334601
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia., PMID:38360867
Characterization of the Pro-Inflammatory and Pruritogenic Transcriptome in Skin Lesions of the Experimental Canine Atopic Acute IgE-Mediated Late Phase Reactions Model and Correlation to Acute Skin Lesions of Human Atopic Dermatitis., PMID:38535843
Expression of inducible nitric oxide synthase, nitrotyrosine, eosinophilic peroxidase, eotaxin-3, and galectin-3 in patients with gastroesophageal reflux disease, eosinophilic esophagitis, and in healthy controls: a semiquantitative image analysis of 3,3'-diaminobenzidine-stained esophageal biopsies., PMID:38679488
Targeting CCL24 in Inflammatory and Fibrotic Diseases: Rationale and Results from Three CM-101 Phase 1 Studies., PMID:38822943
Macrophage activation and inflammatory priming by anti-MAA antibodies in rheumatoid arthritis., PMID:38969267
Airway proteomics reveals broad residual anti-inflammatory effects of prednisolone in mepolizumab-treated asthma., PMID:39097197
Stress-experienced monocytes/macrophages lose anti-inflammatory function via β2-adrenergic receptor in skin allergic inflammation., PMID:39566608
Depletion of eosinophils during sensitization but not challenge phase in mice blocks the development of food allergy early in life., PMID:40073088
For research use only. Not for human or drug use.
