Catalog No.
KDC82801
Stability and Storage
The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Detection method
Colorimetric
Precision
CV<20%
Sample type
Plasma, Serum
Assay type
Quantitative
Sensitivity
0.156 μg/ml
Range
0.31-5 μg/mL
Recovery
80-120%
Specifications
Befovacimab
Alternative Names
BAY-1093884
Background
Bevacizumab is a recombinant human IgG1 monoclonal antibody specific for all human vascular endothelial growth factor-A (VEGF-A) isoforms. The humanized anti-VEGF monoclonal antibody, bevacizumab, has been approved by the FDA as a first-line treatment for metastatic colorectal cancer in combination with chemotherapy. The pharmacokinetic properties of bevacizumab in several species have been previously described and are consistent with a typical humanized monoclonal antibody. It was shown in the literature that the surveillance of circulating concentration during maintenance therapy represents a direct and/or indirect factor for some other side effects. Identification of biomarkers for (non-)response and risk factors for adverse drug reactions that might be related to serum concentrations and maintaining the effective concentration of Bevacizumab in order to potentially avoid some side effects with a reliable method might be beneficial.
Shipping
2-8 ℃
Note
For Research Use Only.
For research use only. Not for human or drug use.
