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Mouse IgG2C Isotype Control Antibody (HyHEL-10)

Catalog #:   FMB96910 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2C
Applications: FCM, Isotype Control
Overview

Catalog No.

FMB96910

Host species

Mouse

Isotype

IgG2C

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

FCM, Isotype Control

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

HyHEL-10

Note

For research use only.

Data Image
  • SDS-PAGE
    SDS PAGE for Mouse IgG2C Isotype Control Antibody (HyHEL-10)
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Filariae-Retrovirus Co-infection in Mice is Associated with Suppressed Virus-Specific IgG Immune Response and Higher Viral Loads., PMID:27923052

R-Loop Depletion by Over-expressed RNase H1 in Mouse B Cells Increases Activation-Induced Deaminase Access to the Transcribed Strand without Altering Frequency of Isotype Switching., PMID:28065739

Bioengineering a bacterial pathogen to assemble its own particulate vaccine capable of inducing cellular immunity., PMID:28150705

Increased humoral immunity by DNA vaccination using an α-tocopherol-based adjuvant., PMID:28613978

A Combination of Recombinant Mycobacterium bovis BCG Strains Expressing Pneumococcal Proteins Induces Cellular and Humoral Immune Responses and Protects against Pneumococcal Colonization and Sepsis., PMID:28768668

Influence of the Novel ATP-Competitive Dual mTORC1/2 Inhibitor AZD2014 on Immune Cell Populations and Heart Allograft Rejection., PMID:28885497

Virus-like particles vaccine containing Clonorchis sinensis tegumental protein induces partial protection against Clonorchis sinensis infection., PMID:29284528

A lipid A-based TLR4 mimetic effectively adjuvants a Yersinia pestis rF-V1 subunit vaccine in a murine challenge model., PMID:29861179

A clinically applicable adjuvant for an atherosclerosis vaccine in mice., PMID:29932463

Comparison of immunogenicity and vaccine efficacy between heat-shock proteins, HSP70 and GrpE, in the DnaK operon of Mycobacterium tuberculosis., PMID:30258084

Immunogenic reactivity of recombinant PKF and AbOmpA proteins as serum resistance factors against sepsis of Acinetobacter baumannii., PMID:30930220

Enhanced Immunogenicity and Protective Efficacy of a Campylobacter jejuni Conjugate Vaccine Coadministered with Liposomes Containing Monophosphoryl Lipid A and QS-21., PMID:31043512

B cell-intrinsic MyD88 signaling controls IFN-γ-mediated early IgG2c class switching in mice in response to a particulate adjuvant., PMID:31087643

B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B-1-Cell Responses., PMID:31092015

Route of Vaccine Administration Influences the Impact of Fms-Like Tyrosine Kinase 3 Ligand (Flt3L) on Chlamydial-Specific Protective Immune Responses., PMID:31333682

B Cell-Mediated Antigen Presentation through MHC Class II Is Dispensable for Atherosclerosis Progression., PMID:31356175

A lipopolysaccharide-free outer membrane vesicle vaccine protects against Acinetobacter baumannii infection., PMID:31843268

Treatment of Dystrophic mdx Mice with an ADAMTS-5 Specific Monoclonal Antibody Increases the Ex Vivo Strength of Isolated Fast Twitch Hindlimb Muscles., PMID:32156081

GITR shapes humoral immunity by controlling the balance between follicular T helper cells and regulatory T follicular cells., PMID:32259529

Neutrophils Are Required During Immunization With the Pneumococcal Conjugate Vaccine for Protective Antibody Responses and Host Defense Against Infection., PMID:32391562

Measuring of IgG2c isotype instead of IgG2a in immunized C57BL/6 mice with Plasmodium vivax TRAP as a subunit vaccine candidate in order to correct interpretation of Th1 versus Th2 immune response., PMID:32619431

Adjuvant effects of killed Lactobacillus casei DK128 on enhancing T helper type 1 immune responses and the efficacy of influenza vaccination in normal and CD4-deficient mice., PMID:32674907

A lymph node-targeted Amphiphile vaccine induces potent cellular and humoral immunity to SARS-CoV-2., PMID:33547083

Immune response of C57BL/6J mice to herpes zoster subunit vaccines formulated with nanoemulsion-based and liposome-based adjuvants., PMID:34634689

Single-cell transcriptome profiling and the use of AID deficient mice reveal that B cell activation combined with antibody class switch recombination and somatic hypermutation do not benefit the control of experimental trypanosomosis., PMID:34762705

Development of an Intranasal Gel for the Delivery of a Broadly Acting Subunit Influenza Vaccine., PMID:35353486

STING Is Required in Conventional Dendritic Cells for DNA Vaccine Induction of Type I T Helper Cell- Dependent Antibody Responses., PMID:35529875

Disruption of sncRNA Improves the Protective Efficacy of Outer Membrane Vesicles against Helicobacter pylori Infection in a Mouse Model., PMID:35861532

Type I Interferons Promote Germinal Centers Through B Cell Intrinsic Signaling and Dendritic Cell Dependent Th1 and Tfh Cell Lineages., PMID:35911733

Single-stranded RNA adjuvant enhances the efficacy of 10-valent human papilloma virus-like particle vaccine., PMID:35979884

AFF3, a susceptibility factor for autoimmune diseases, is a molecular facilitator of immunoglobulin class switch recombination., PMID:36001653

Multidomain peptide hydrogel adjuvants elicit strong bias towards humoral immunity., PMID:36102692

LigA formulated in AS04 or Montanide ISA720VG induced superior immune response compared to alum, which correlated to protective efficacy in a hamster model of leptospirosis., PMID:36300125

Post-fusion influenza vaccine adjuvanted with SA-2 confers heterologous protection via Th1-polarized, non-neutralizing antibody responses., PMID:37330368

B cell-intrinsic TLR7 signaling is required for neutralizing antibody responses to SARS-CoV-2 and pathogen-like COVID-19 vaccines., PMID:37438976

Bullous pemphigoid induced by IgG targeting type XVII collagen non-NC16A/NC15A extracellular domains is driven by Fc gamma receptor- and complement-mediated effector mechanisms and is ameliorated by neonatal Fc receptor blockade., PMID:37929639

Multimodal vaccination targeting the receptor binding domains of Clostridioides difficile toxins A and B with an attenuated Salmonella Typhimurium vector (YS1646) protects mice from lethal challenge., PMID:38189293

Robust Immune Response and Protection against Lethal Pneumococcal Challenge with a Recombinant BCG-PspA-PdT Prime/Boost Scheme Administered to Neonatal Mice., PMID:38400107

Immunogenicity and protective efficacy of Ag85A and truncation of PstS1 fusion protein vaccines against tuberculosis., PMID:38463854

Boosting the immune response in COVID-19 vaccines via an Alum:CpG complex adjuvant., PMID:38964615

A viral vaccine design harnessing prior BCG immunization confers protection against Ebola virus., PMID:39081315

A vaccine candidate based on baculovirus displaying chikungunya virus E1-E2 envelope confers protection against challenge in mice., PMID:39440961

Bifidobacterium breve M-16 V and scGOS/lcFOS Supplementation to Dams Ameliorates Infant Rotavirus Infection in Early Life., PMID:39468988

Skin autonomous antibody production regulates host-microbiota interactions., PMID:39662506

Mucosal vaccination with outer membrane vesicles derived from Bordetella pertussis reduces nasal bacterial colonization after experimental infection., PMID:39669568

Evaluating the Immunoprotective and Diagnostic Potential of Schistosoma mansoni Epitopes from Sm050890 and Sm141290 Proteins Identified Through Reverse Vaccinology., PMID:39775981

Immunogenicity in mice and non-human primates of an Advax-CpG55.2-adjuvanted recombinant hemagglutinin seasonal quadrivalent influenza vaccine., PMID:39798433

Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD., PMID:39899881

The novel antigen, lipopolysaccharide export protein LptH, protects mice against Pseudomonas aeruginosa acute pneumonia in monovalent and multivalent vaccines., PMID:40262371

Development of a single-dose Q fever vaccine with an injectable nanoparticle-loaded hydrogel: effect of sustained co-delivery of antigen and adjuvant., PMID:40314164

Datasheet
$ 160
Product specifications
50 μg 160 100 μg 260

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For research use only. Not for human or drug use.

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Mouse IgG2C Isotype Control Antibody (HyHEL-10) [FMB96910]
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