Anti-Human CD49f/ITGA6 Antibody (P2D10)

Catalog No.

FHD56010

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

CD49 antigen-like family member F, Integrin alpha-6, ITGA6, VLA-6, CD49f, Alpha6p

Concentration

0.6 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P23229

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

P2D10

Epithelial eversion, a collective rearrangement from apical-in to apical-out polarity, is initiated by α6β4 integrins and sustained by increased cell proliferation and anchorage-independence., PMID:40463241

DNA Ligase 4 Inhibition Sensitizes Prostate Cancer to Immune Checkpoint Blockade In Vivo., PMID:40037856

Recombinant human collagen XVII protects skin basement membrane integrity by inhibiting the MAPK and Wnt signaling pathways., PMID:39981899

Methodologic considerations on how to identify human hematopoietic stem cells., PMID:39892848

Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy., PMID:39515328

FUT3 promotes gastric cancer cell migration by synthesizing Lea on ITGA6 and GLG1, affecting adhesion and vesicle distribution., PMID:39477144

Phenotypic Shift of an Inflammatory Eosinophil Subset into a Steady-State Resident Phenotype after 2 Years of Vaccination against IL-5 in Equine Insect Bite Hypersensitivity., PMID:39453068

The potential role of collagen type VII in breast cancer proliferation., PMID:39030607

Impact of brain organoid-derived sEVs on metastatic adaptation and invasion of breast carcinoma cells through a microphysiological system., PMID:38888211

Flow cytometric immunophenotypic differentiation patterns of bone marrow eosinophilopoiesis., PMID:38666394

Involvement of BCR::ABL1 in laminin adhesion of Philadelphia chromosome-positive  acute lymphoblastic leukemia through upregulation of integrin α6., PMID:38577721

Faster clinical decisions in B-cell acute lymphoblastic leukaemia: A single flow cytometric 12-colour tube improves diagnosis and minimal residual disease follow-up., PMID:38432068

Decreased B4GALT1 promotes hepatocellular carcinoma cell invasiveness by regulating the laminin-integrin pathway., PMID:37907465

Comprehensive cell surface protein profiling of human mesenchymal stromal cells from peritoneal dialysis effluent and comparison with those from human bone marrow and adipose tissue., PMID:37603218

Characterization of Porcine Ocular Surface Epithelial Microenvironment., PMID:37108705

Inverse agonists of retinoic acid receptor/retinoid X receptor signaling as lineage-specific antitumor agents against human adenoid cystic carcinoma., PMID:37040084

Native Autoantigen Complex Detects Pemphigoid Autoantibodies., PMID:36992950

Comparative analysis of EpCAM high-expressing and low-expressing circulating tumour cells with regard to their clonal relationship and clinical value., PMID:36823365

Endothelial cell‑derived connective tissue growth factor stimulates fibroblast differentiation into myofibroblasts through integrin αVβ3., PMID:36561611

Identification and Isolation of Burst-Forming Unit and Colony-Forming Unit Erythroid Progenitors from Mouse Tissue by Flow Cytometry., PMID:36408979

Immortalised canine buccal epithelial cells' CXCL8 secretion is affected by allergen extracts, Toll-like receptor ligands, IL-17A and calcitriol., PMID:36100942

Synovial fluid niche promoted differentiation of dental follicle mesenchymal stem cells toward chondrogenesis in rheumatoid arthritis., PMID:35949879

Integrin alpha 6 is upregulated and drives hepatocellular carcinoma progression through integrin α6β4 complex., PMID:35657344

Laminin Triggers Neutrophil Extracellular Traps (NETs) and Modulates NET Release Induced by Leishmania amazonensis., PMID:35327324

Functional characterization of CD49f+ hepatic stem/progenitor cells in adult mice liver., PMID:35166962

Quantitative Cell Subset Analysis Using Antibody Microarrays., PMID:35006690

Laminin Isoforms in Human Dental Pulp: Lymphatic Vessels Express Laminin-332, and Schwann Cell-Associated Laminin-211 Modulates CD163 Expression of M2-like Macrophages., PMID:34965967

Microfluidic chip for rapid and selective isolation of tumor-derived extracellular vesicles for early diagnosis and metastatic risk evaluation of breast cancer., PMID:34273737

High-throughput surface marker screen on primary human breast tissues reveals further cellular heterogeneity., PMID:34120626

Phenotypical Characterization and Neurogenic Differentiation of Rabbit Adipose Tissue-Derived Mesenchymal Stem Cells., PMID:33802902

Evaluation of CD49f as a novel surface marker to identify functional adipose-derived mesenchymal stem cell subset., PMID:33704842

Pharmacological HIF-1 stabilization promotes intestinal epithelial healing through regulation of α-integrin expression and function., PMID:33470153

Defining phenotypic and functional heterogeneity of glioblastoma stem cells by mass cytometry., PMID:33400685

Simultaneous Fluorescent Identification of Odontoblasts and Ameloblasts., PMID:33289448

Hepatic stellate cells contribute to liver regeneration through galectins in hepatic stem cell niche., PMID:32993816

Screening of integrins localized on the surface of human epidermal melanocytes., PMID:32572848

Characterizing the Motility of Chemotherapeutics-Treated Acute Lymphoblastic Leukemia Cells by Time-Lapse Imaging., PMID:32560076

Flow-induced Reorganization of Laminin-integrin Networks Within the Endothelial Basement Membrane Uncovered by Proteomics., PMID:32332107

Galectin-1-Related Modulation of Trophoblast Endothelial Interactions by Integrins α1 and β1., PMID:32253734

Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia., PMID:32219444

Expression and distribution of CD151 as a partner of alpha6 integrin in male germ cells., PMID:32152440

Integrin ανβ6 Protein Expression and Prognosis in Solid Tumors: A Meta-Analysis., PMID:32100239

Phenotypic and microRNA characterization of the neglected CD24+ cell population in MCF-7 breast cancer 3-dimensional spheroid culture., PMID:31904742

Integrin Antibody Decreases Deformability of Patient-Derived Pre-B Acute Lymphocytic Leukemia Cells as Measured by High-Frequency Acoustic Tweezers., PMID:31633840

The dystroglycan receptor maintains glioma stem cells in the vascular niche., PMID:31463571

Differential Regulation of T-cell Immunity and Tolerance by Stromal Laminin Expressed in the Lymph Node., PMID:31343575

[Not Available]., PMID:31082464

Integrin α10, a Novel Therapeutic Target in Glioblastoma, Regulates Cell Migration, Proliferation, and Survival., PMID:31027305

TLR4 increases the stemness and is highly expressed in relapsed human hepatocellular carcinoma., PMID:30957973

Surgical resection of breast cancers: Molecular analysis of cancer stem cells in residual disease., PMID:30777364

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