Catalog No.
FHB60010
Species reactivity
Human
Host species
Human
Isotype
IgG1, lambda
Clonality
Monoclonal
Conjugation
Unconjugated
Target
C4.4A, Matrigel-induced gene C4 protein, GPI-anchored metastasis-associated protein C4.4A homolog, MIG-C4, LYPD3, Ly6/PLAUR domain-containing protein 3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O95274
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0109
A High-Affinity Monoclonal Antibody Against the Pancreatic Ductal Adenocarcinoma Target, Anterior Gradient-2 (AGR2/PDIA17)., PMID:39727484
A Novel NAMPT Inhibitor-Based Antibody-Drug Conjugate Payload Class for Cancer Therapy., PMID:35658441
Crystal Structures of Human C4.4A Reveal the Unique Association of Ly6/uPAR/α-neurotoxin Domain., PMID:32140067
The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer., PMID:31644911
Preclinical Antitumor Efficacy of BAY 1129980-a Novel Auristatin-Based Anti-C4.4A (LYPD3) Antibody-Drug Conjugate for the Treatment of Non-Small Cell Lung Cancer., PMID:28292941
New Blocking Antibodies against Novel AGR2-C4.4A Pathway Reduce Growth and Metastasis of Pancreatic Tumors and Increase Survival in Mice., PMID:25646014
The metastasis-associated molecule C4.4A promotes tissue invasion and anchorage independence by associating with the alpha6beta4 integrin., PMID:23727360
C4.4A expression is associated with a poor prognosis of esophageal squamous cell carcinoma., PMID:23435632
Distinct expression of C4.4A in colorectal cancer detected by different antibodies., PMID:23175173
Expression of C4.4A in precursor lesions of pulmonary adenocarcinoma and squamous cell carcinoma., PMID:21792890
Expression of C4.4A, a structural uPAR homolog, reflects squamous epithelial differentiation in the adult mouse and during embryogenesis., PMID:21339181
Expression of C4.4A at the invasive front is a novel prognostic marker for disease recurrence of colorectal cancer., PMID:20825414
C4.4A as a candidate marker in the diagnosis of colorectal cancer., PMID:17912244
Tumour cell expression of C4.4A, a structural homologue of the urokinase receptor, correlates with poor prognosis in non-small cell lung cancer., PMID:17706320
Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor., PMID:15012588
Cloning and functional characterization of a new phosphatidyl-inositol anchored molecule of a metastasizing rat pancreatic tumor., PMID:9788443
For research use only. Not for human or drug use.
