Catalog No.
RVV08623
Expression system
Mammalian Cells
Species reactivity
Hepatitis C virus genotype 1a (isolate H77) (HCV) & Hepatitis C virus genotype 1b (isolate Japanese) (HCV)
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
NS1, gp68, gp70, Envelope glycoprotein E2, Genome polyprotein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P27958, P26662
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
L1
PD-L1 expression in human cancers and its association with clinical outcomes. PMID: 27574444
Non-cytomembrane PD-L1: An atypical target for cancer. PMID: 34174446
Emerging role of PD-L1 modification in cancer immunotherapy. PMID: 34522452
PD-L1: expression regulation. PMID: 37228770
Biological Characteristics and Clinical Significance of Soluble PD-1/PD-L1 and Exosomal PD-L1 in Cancer. PMID: 35386715
Tumor extracellular vesicles mediate anti-PD-L1 therapy resistance by decoying anti-PD-L1. PMID: 36220994
PD-L1 expression as a predictive biomarker for immune checkpoint inhibitors: between a dream and a nightmare. PMID: 34190579
PD-L1 expression in sarcomas: An immunohistochemical study and review of the literature. PMID: 34656856
Inhibitory Effect of PD-1/PD-L1 and Blockade Immunotherapy in Leukemia. PMID: 34238150
The Prognostic and Therapeutic Value of PD-L1 in Glioma. PMID: 30687086
L1-CAM as a target for treatment of cancer with monoclonal antibodies. PMID: 20044598
Exosomal PD-L1: New Insights Into Tumor Immune Escape Mechanisms and Therapeutic Strategies. PMID: 33178688
PD-L1 in circulating exosomes of Merkel cell carcinoma. PMID: 34994009
Soluble Programmed Death Ligand-1 (sPD-L1): A Pool of Circulating Proteins Implicated in Health and Diseases. PMID: 34204509
Challenges and the Evolving Landscape of Assessing Blood-Based PD-L1 Expression as a Biomarker for Anti-PD-(L)1 Immunotherapy. PMID: 35625917
L1 (LINE-1) retrotransposon diversity differs dramatically between mammals and fish. PMID: 14698614
Comparison of PD-L1 immunohistochemical assays and the significance of PD-L1 expression in thymoma. PMID: 33447446
An update on companion and complementary diagnostic assays for PD-1/PD-L1 checkpoint inhibitors in NSCLC. PMID: 33896308
PD-L1 protein expression in relation to recurrence score values in early-stage ER + breast cancer. PMID: 36028784
Homophilic interaction of the L1 family of cell adhesion molecules. PMID: 22573111
Ubiquitin C-terminal hydrolase-L1 (UCH-L1) as a therapeutic and diagnostic target in neurodegeneration, neurotrauma and neuro-injuries. PMID: 28434268
Mitochondrial and Neuronal Dysfunctions in L1 Mutant Mice. PMID: 35457156
Tumor PD-L1 Induction by Resveratrol/Piceatannol May Function as a Search, Enhance, and Engage ("SEE") Signal to Facilitate the Elimination of "Cold, Non-Responsive" Low PD-L1-Expressing Tumors by PD-L1 Blockade. PMID: 31783532
The function of neuropilin/L1 complex. PMID: 12613546
Prognostic value of PD-L1 expression in bronchopulmonary neuroendocrine tumours. PMID: 33475525
The recent evolution of human L1 retrotransposons. PMID: 16093692
Concordance of PD-L1 expression in triple-negative breast cancers in Chinese patients: A retrospective and pathologist-based study. PMID: 36152566
On the Link Between L1-PCA and ICA. PMID: 27337712
PD-L1 blockade enhances anti-tumor efficacy of NK cells. PMID: 30377572
Soluble PD-L1 Expression After Intravenous Treatment of Cancer Patients With Selenite in Phase I Clinical Trial. PMID: 35720000
The Cell Adhesion Molecule L1 Interacts with Methyl CpG Binding Protein 2 via Its Intracellular Domain. PMID: 35408913
The cell adhesion molecule L1: species- and cell-type-dependent multiple binding mechanisms. PMID: 9084132
Evaluation of PD-L1 expression in a large set of gastroenteropancreatic neuroendocrine tumours and correlation with clinicopathological data. PMID: 36067541
Cell adhesion molecule L1 interacts with the chromo shadow domain of heterochromatin protein 1 isoforms α, β, and ɣ via its intracellular domain. PMID: 34859928
Epstein-Barr Virus LMP1 Induces Soluble PD-L1 in Nasopharyngeal Carcinoma. PMID: 33804064
PD-L1 Is a Tumor Suppressor in Aggressive Endometrial Cancer Cells and Its Expression Is Regulated by miR-216a and lncRNA MEG3. PMID: 33363153
Human and mouse PD-L1: similar molecular structure, but different druggability profiles. PMID: 33437940
Bafetinib Suppresses the Transcription of PD-L1 Through c-Myc in Lung Cancer. PMID: 35721177
Revisiting the proteolytic processing of cell adhesion molecule L1. PMID: 32986867
For research use only. Not for human or drug use.
