Anti-HRSV-A F/Fusion glycoprotein F0 Antibody (MPE8)

Catalog No.

RVV02814

Description

This antibody neutralizes HRSV and HMPV isolates of several subgroups.

Expression system

Mammalian Cells

Species reactivity

Human respiratory syncytial virus A (strain A2),Human metapneumovirus

Host species

Human

Isotype

IgG1, lambda2

Clonality

Monoclonal

Target

F, Fusion glycoprotein F0, Protein F, CR13039

Concentration

3.78 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03420

Applications

ELISA, SPR

Form

Liquid

Storage buffer

100 mM Pro-Ac, 20 mM Arg, pH 5.0

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

MPE8

Dissociation of the respiratory syncytial virus F protein-specific human IgG, IgA and IgM response., PMID:33574352

Prefusion F, Postfusion F, G Antibodies, and Disease Severity in Infants and Young Children With Acute Respiratory Syncytial Virus Infection., PMID:29029312

Membrane-associated respiratory syncytial virus F protein expressed from a human rhinovirus type 14 vector is immunogenic., PMID:11277694

Intracellular processing of the human respiratory syncytial virus fusion glycoprotein: amino acid substitutions affecting folding, transport and cleavage., PMID:1375280

Enhanced pulmonary histopathology is observed in cotton rats immunized with formalin-inactivated respiratory syncytial virus (RSV) or purified F glycoprotein and challenged with RSV 3-6 months after immunization., PMID:2251875

Document Download

Anti-HRSV-A F/Fusion glycoprotein F0 Antibody (MPE8).pdf