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Research Grade Anti-Human CD66e/CEA/CEACAM5 Antibody (cT84.66)

Catalog #:   DHC21005 Specific References (56) DATASHEET
Host species: Chimeric
Isotype: IgG1
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHC21005

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Chimeric

Isotype

IgG1

Clonality

Monoclonal

Applications

Research Grade Biosimilar

Target

Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06731

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

90Y-cT84.66,T84.66

Clone ID

cT84.66

Note

For research use only. Not suitable for clinical or therapeutic use.

Data Image
  • Bioactivity
    Detects Human CD66e/CEA/CEACAM5 in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for 90Y-cT84.66
References

Lenvatinib, sintilimab combined interventional treatment vs bevacizumab, sintilimab combined interventional treatment for intermediate-advanced unresectable hepatocellular carcinoma., PMID:39575400

Neisseria gonorrhoeae induces local secretion of IL-10 at the human cervix to promote colonization., PMID:39585777

A bio-nano-engineered platform fabricated from cerium oxide-carbon nanoparticles stabilized with chitosan for label-free sensing of a lung cancer biomarker., PMID:39633582

Enrichment of carcinoembryonic antigen by epitope molecularly imprinted polymer based on cucurbituril host-guest interaction., PMID:39644742

Antibody-modified 2D MXene nanosheet probes for selective, picolevel detection of cancer biomarkers., PMID:39647410

Carcinoembryonic Antigen Expression in Human Tumors: A Tissue Microarray Study on 13,725 Tumors., PMID:39682238

Expression-Dependent Tumor Pretargeting via Engineered Avidity., PMID:39704255

Point-of-Care Detection of Carcinoembryonic Antigen (CEA) Using a Smartphone-Based, Label-Free Electrochemical Immunosensor with Multilayer CuONPs/CNTs/GO on a Disposable Screen-Printed Electrode., PMID:39727865

Impedimetric Biosensors for the Quantification of Serum Biomarkers for Early Detection of Lung Cancer., PMID:39727890

Characteristics of Nodular Goitre and Its Correlation With Papillary Thyroid Carcinoma: A Cross-Sectional Study., PMID:39737304

The Nonclinical Safety Assessment of a Novel Anti-CEACAM5 Antibody Exatecan Conjugate Predicts a Low Risk for Interstitial Lung Disease (ILD) in Patients-The Putative Mechanism Behind ILD., PMID:39754485

Targeting CEA in metastatic triple negative breast cancer with image-guided radiation followed by Fab-mediated chimeric antigen receptor (CAR) T-cell therapy., PMID:39759518

Electrochemical biosensor based on composite of gold nanoparticle/reduced-graphene oxide/graphitic carbon nitride and a caprolactone polymer for highly sensitive detection of CEA., PMID:39764934

Affinity Peptide-Based Circularly Permuted Fluorescent Protein Biosensors for Non-Small Cell Lung Cancer Diagnosis., PMID:39771637

Antibody-Drug Conjugates in Non-Small Cell Lung Cancer: State of the Art and Future Perspectives., PMID:39796075

Broad-Spectrum Efficacy of CEACAM6-Targeted Antibody-Drug Conjugate with BET Protein Degrader in Colorectal, Lung, and Breast Cancer Mouse Models., PMID:39812376

Reanalysis of Urothelial Cancer Chemoimmunotherapy Trials With Differential Censoring., PMID:39841472

Bright and Specific Targeting of Metastatic Lymph Nodes in Orthotopic Mouse Models of Gastric Cancer with a Fluorescent Anti-CEA Antibody., PMID:39878844

Alkaline Phosphatase: A Prognostic Biomarker in Non-Metastatic Colon Adenocarcinoma Patients - A Single-Centre Study., PMID:39936196

Bi2WO6-labeled antibody induced photocurrent polarity switching of ZnIn2S4-based photoelectrochemical immunosensor for the highly sensitive detection of carcinoembryonic antigen., PMID:39951987

Multifunctional dopamine-modified conjugated polymer nanoparticles for ultrasensitive immunoassays., PMID:39955906

Bidirectionally Favorable Platform: A Dual-Targeting Probe-Encoded Maple Leaf-Type Fluorescent Lateral Flow Immunoassay for Multiple Biomarker Detection., PMID:39962727

A Dual Nano-Signal Probe-Based Electrochemical Immunosensor for the Simultaneous Detection of Two Biomarkers in Gastric Cancer., PMID:39996982

Ultrasensitive CEA detection using SiO2/AuNPs-mediated dual inhibition in a signal-off-type photoelectrochemical immunosensor., PMID:40015784

Integrated Device for Cancer Nucleic Acid Biomarker Detection at Body Temperature., PMID:40047709

Highly sensitive detection of carcinoembryonic antigen via an electrochemical platform fabricated by CCLP- gold nanocomposite., PMID:40049234

Gold Nanoparticle Incorporated Graphene Oxide as a SERS Platform for Ultratrace Antibody Free Sensing of the Cancer Biomarker CEA., PMID:40062598

Harnessing bifunctional nanozyme with potent catalytic and signal amplification for innovating electrochemical immunoassay., PMID:40064571

Development of Anti-CEA CH2 Domain-Deleted Antibody (M5A∆CH2) for the PET Imaging of Colorectal Cancer., PMID:40085171

Cerebrospinal fluid cytology for the diagnosis of lung cancer brain metastasis: a case report., PMID:40114958

New World Primates and Their Human Counterparts Share Diseases That Abound with CEACAM and Other Effector Molecules., PMID:40141825

A high-affinity antibody-drug conjugates Actuximab-MMAE for potent and selective targeting of CEACAM5-Positive tumors., PMID:40158720

FOLFIRI with cetuximab or bevacizumab in RAS wild-type metastatic colorectal cancer: Refining first-line treatment selection by combining clinical parameters: A post hoc analysis of the randomized open-label phase III trial FIRE-3/AIO KRK0306., PMID:40179821

Multimodal carcinoembryonic antigen-targeted fluorescence and radio-guided cytoreductive surgery for peritoneal metastases of colorectal origin: single-arm confirmatory trial., PMID:40270484

Dual-channel, real-time, long-term stable electrochemical immunosensor based on Au, Cu-vertical graphene for detection of carcinoembryonic antigen in tumor cells., PMID:40274336

Plasma IgG and IgM autoantibodies to COPT1 as potential biomarkers for detection of non-small cell lung cancer., PMID:40292291

Self-assembled nano-hybrid composite based on Cu/CuXO nanoflower decorated onto hBNNS for high-performance and ultra-sensitive electrochemical detection of CEA biomarker., PMID:40315690

Bifunctional S-doping-mediated interfacial gradient electric field for in-situ amplified photoelectrochemical immunoassay., PMID:40319725

Artificial intelligence prediction of carcinoembryonic antigen structure and interactions relevant for colorectal cancer., PMID:40330074

Modulation of Aggregation of Covalent Organic Framework Nanosheets with Aggregation-Induced Emission Activity for Ultrasensitive No-Wash Fluorescent Immunosensor., PMID:40377048

Phase 1 study evaluating safety and pharmacokinetics of tusamitamab ravtansine monotherapy in Japanese patients with advanced malignant solid tumors., PMID:40413667

Trace protein detection by graphene-integrated terahertz meta-sensor and enhanced sensitivity using gold nanoparticles-assisted., PMID:40413992

An innovative electrophoresis-coupled electrochemiluminescence immunosensor for rapid and sensitive detection of carcinoembryonic antigen., PMID:40418863

CEACAM1 as a mediator of B-cell receptor signaling in mantle cell lymphoma., PMID:40436855

Nanobody-Directed CEA-targeting CAR T Cells Eliminate Gastrointestinal Cancer Xenografts., PMID:40439687

A Phase I Study of the Anti-CEACAM6 Antibody Tinurilimab (BAY 1834942) in Patients with Advanced Solid Tumors., PMID:40465170

Construction of a simple PEC immunosensing platform based on polydopamine and PEDOT sensitized Bi2WO6 for sensitive detection of carcinoembryonic antigen., PMID:40466205

Application of serum anti-ENO1 and anti-SSNA1 antibody biomarkers in predicting the prognosis of gastric cancer., PMID:40469915

Diagnostic significance of carcinoembryonic antigen and anti-MDA5 antibodies in polymyositis/dermatomyositis-associated rapidly progressive interstitial lung disease., PMID:40516211

A Prognostic Index for Advanced Biliary Tract Cancer Treated With Cisplatin, Gemcitabine and Durvalumab: The MAGIC-D Index., PMID:40525496

Estimating residence times and their associated errors in patient absorbed-dose calculation, PMID: 9438927

Breast-tumor xenograft targeting and therapy studies using radiolabeled chimeric anti-cea monoclonal-antibody t84.66, PMID: 21597719

Intrapatient consistency of imaging biodistributions and their application to predicting therapeutic doses in a phase I clinical study of 90Y-based radioimmunotherapy, PMID: 10360545

Initial clinical experience evaluating Yttrium-90-chimeric T84.66 anticarcinoembryonic antigen antibody and autologous hematopoietic stem cell support in patients with carcinoembryonic antigen-producing metastatic breast cancer, PMID: 10541368

Dose escalation trial of indium-111-labeled anti-carcinoembryonic antigen chimeric monoclonal antibody (chimeric T84.66) in presurgical colorectal cancer patients, PMID: 9867150

A Phase I trial of 90Y-anti-carcinoembryonic antigen chimeric T84.66 radioimmunotherapy with 5-fluorouracil in patients with metastatic colorectal cancer, PMID: 14676105

Datasheet
$ 320
Product specifications
100 μg 320 1 mg 1280 5 mg 3840

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Anti-Human CD66e/CEA/CEACAM5 Antibody (cT84.66) [DHC21005]
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