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Research Grade Anti-Human IL8/CXCL8 Antibody (ABX-IL8) (DHC79102)

Host species:Human
Isotype:IgG2-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHC79102

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG2-kappa

Clonality

Monoclonal

Target

GCP/IL-8 protein II, MDNCF, IL8/NAP1 form III, IL-8(1-77), Neutrophil-activating factor, GCP/IL-8 protein I, GCP/IL-8 protein VI, Interleukin-8, Chemokine (C-X-C motif) ligand 8, Neutrophil-activating protein 1, Monocyte-derived neutrophil chemotactic factor, (Ser-IL-8)72, MDNCF-b, LYNAP, GCP/IL-8 protein V, IL8/NAP1 form IV, MONAP, IL8/NAP1 form V, IL8/NAP1 form VI, NAP-1, Granulocyte chemotactic protein 1, GCP/IL-8 protein III, IL8/NAP1 form II, IL8, IL-8, CXCL8, IL8/NAP1 form I, (Ala-IL-8)77, Protein 3-10C, GCP/IL-8 protein IV, Emoctakin, GCP-1, C-X-C motif chemokine 8, NAF, T-cell chemotactic factor, MDNCF-c, Monocyte-derived neutrophil-activating peptide, Lymphocyte-derived neutrophil-activating factor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P10145

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

ABX-IL8

Clone ID

ABX-IL8

Data Image
  • SDS-PAGE
    SDS PAGE for ABX-IL8
  • Bioactivity
    Detects IL8/CXCL8 in indirect ELISAs.
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma, PMID: 12107097

Population pharmacokinetic evaluation of a fully human IgG monoclonal antibody in patients with inflammatory diseases, PMID: 20860546

Bioimmunotherapy for melanoma using fully human antibodies targeting MCAM/MUC18 and IL-8, PMID: 16965268

Tumor immunotherapy in melanoma: strategies for overcoming mechanisms of resistance and escape, PMID: 18717605

Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB, PMID: 12912969

Emerging biological therapies for treating chronic obstructive pulmonary disease: A pairwise and network meta-analysis, PMID: 29609004

Influence of histidine on the stability and physical properties of a fully human antibody in aqueous and solid forms, PMID: 14725359

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Anti-Human IL8/CXCL8 Antibody (ABX-IL8) [DHC79102]
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