Catalog No.
EHJ51603
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Ser19-Asp615
Predicted molecular weight
98.9 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BYF1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Angiotensin-converting enzyme homolog, ACE2, ACEH, Metalloprotease MPROT15, Angiotensin-converting enzyme-related carboxypeptidase, Angiotensin-converting enzyme 2, ACE-related carboxypeptidase, SARS-like Coronaviruses
Exploring anti-SARS-CoV-2 natural products: dual-viral target inhibition by delphinidin and the anti-coronaviral efficacy of deapio platycodin D., PMID:40512442
Comprehensive analysis of SARS-CoV-2 Spike evolution: epitope classification and immune escape prediction., PMID:40510757
A novel cellular tool for screening human pan-coronavirus antivirals., PMID:40505777
Convergent evolution in nucleocapsid facilitated SARS-CoV-2 adaptation for human infection., PMID:40503915
Molecular mechanisms of SARS-CoV-2 entry: implications for biomedical strategies., PMID:40503878
Multi-Omic Profiling Identifies Conserved Metabolic Pathways Critical for SARS-CoV-2 Variants Infection., PMID:40502071
Development and Validation of Novel Cell-free Direct Neutralization Assay for SARS-CoV-2., PMID:40499786
Carotid Body Size on CT Angiography in Patients With COVID-19 Pneumonia., PMID:40496438
SARS-CoV-2 exploits steroidogenic machinery, triggers lipid metabolism for viral replication and induces immune response in Leydig cells of K18-hACE2 mice., PMID:40496014
Modulation of SARS-CoV-2 spike binding to ACE2 through conformational selection., PMID:40494932
Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population., PMID:40491571
Predicting high-fitness viral protein variants with Bayesian active learning and biophysics., PMID:40489612
Glycyrrhizic acid mitigates hepatocyte steatosis and inflammation through ACE2 stabilization via dual modulation of AMPK activation and MDM2 inhibition., PMID:40484334
Picomolar bivalent inhibitors of protein kinase CK2 active against β-coronavirus replication., PMID:40482595
Safety and immunogenicity of four sequential doses of NVX-CoV2373 in adults and adolescents: A phase 3, randomized, placebo-controlled trial (PREVENT-19)., PMID:40479932
Genetic and Inflammatory Signatures Associated With Worse Prognosis in Hospitalized Patients With Severe SARS-CoV-2 Infection With and Without Diabetes., PMID:40476695
Unmasking complex kinetics in viral entry by inferring hypoexponential models., PMID:40475676
Exploring Spike-Dependent and ACE2-Independent Viral Entry into Salivary Epithelial Cells in the Absence of ACE2., PMID:40475672
Deletion of the Envelope gene attenuates SARS-CoV-2 infection by altered Spike localization and increased cell-to-cell transmission., PMID:40475451
Influence of Cholesterol on the Insertion and Interaction of SARS-CoV-2 Proteins with Lipid Membranes., PMID:40474679
Clarification of author disclosures in the article "Angiotensin converting enzyme 2 and angiotensin (1-7) axis in pulmonary arterial hypertension"., PMID:40473302
[Mechanistic study on low expression of Ace2 gene activated senescence-related signals and promoted the progression of silicotic fibrosis in mice]., PMID:40468507
Mechanism of ferroptosis in hypoxia-induced pulmonary vascular remodeling in hypoxia pulmonary hypertension: a study based on the ACE2-Ang-(1-7)-Mas axis., PMID:40466901
Cytogenetic Alterations Observed in Exfoliative Cells of the Tongue and Oral Mucosa of SARS-CoV-2-Vaccinated Patients: Report of Two Cases and a Brief Literature Review., PMID:40465890
Potential Inhibitors of SARS-CoV-2 Developed through Machine Learning, Molecular Docking, and MD Simulation., PMID:40464176
Unveiling the structural spectrum of SARS-CoV-2 fusion by in situ cryo-ET., PMID:40461447
Multi-level inhibition of SARS-CoV-2 invasion by cannabidiol and epigallocatechin gallate., PMID:40460494
EXPRESS: Polymorphism of Angiotensin-Converting Enzyme 2 Gene (rs 2285666) and its Susceptibility for Covid-19 Infection and Severity of the Disease., PMID:40459007
Correlation between orthostatic intolerance in children and levels of ACE2-Ang(1-7)-Mas axis and vitamin D., PMID:40453223
Neuroleptic malignant syndrome in a patient with COVID-19 and the possible role of SARS-CoV-2 in its manifestation: case report and overview of published cases., PMID:40450224
Allostery Links hACE2 Binding, Pan-variant Neutralization and Helical Extension in the SARS-CoV-2 Spike Protein., PMID:40447075
Multiplex ACE2-RBD binding inhibition assay: An integrated tool for assessing neutralizing antibodies to SARS-CoV-2 variants and protection against breakthrough infections., PMID:40447072
SARS-CoV-2 infection of human cortical cells is influenced by the interaction between aneuploidy and biological sex: insights from a Down syndrome in vitro model., PMID:40445428
Broad-spectrum coronavirus inhibitors discovered by modeling viral fusion dynamics., PMID:40443526
Pathological Glucose Levels Enhance Entry Factor Expression and Hepatic SARS-CoV-2 Infection., PMID:40442985
ACE2 shedding exacerbates sepsis-induced gut leak via loss of microbial metabolite 5-methoxytryptophan., PMID:40442816
Modulating the renin-angiotensin system by eprosartan or xanthenone drives microglial M2 polarization in a rat model of Parkinson's disease via regulating the interplay between MKP-1/ miR-155 /SOCS1 and PP2A signaling network., PMID:40440958
ACE2, a therapeutic target of COVID-19, needs to be treated with caution., PMID:40439840
Sulfonohydrazide as a potential inhibitor of SARS-CoV-2 infection., PMID:40437072
ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronaviruses., PMID:40436893
Antibody Response Against SARS-CoV-2 Spike Protein in People with HIV After COVID-19 Vaccination., PMID:40432092
Uncovering SARS-CoV-2 Molecular Epidemiology Across the Pandemic Transition: Insights into Transmission in Clinical and Environmental Samples., PMID:40431737
A Novel Antiviral Therapeutic Platform: Anchoring IFN-β to the Surface of Infectious Virions Equips Interferon-Evasive Virions with Potent Antiviral Activity., PMID:40431708
Receptor Binding for the Entry Mechanisms of SARS-CoV-2: Insights from the Original Strain and Emerging Variants., PMID:40431702
Comparative Examination of Feline Coronavirus and Canine Coronavirus Effects on Extracellular Vesicles Acquired from A-72 Canine Fibrosarcoma Cell Line., PMID:40431570
Impact of pH-Responsive Cisplatin/Ribavirin-Loaded Monodispersed Magnetic Silica Nanocomposite on A549 Lung Cancer Cells., PMID:40430922
Pathophysiological Mechanisms Linking COVID-19 and Acute Surgical Abdomen: A Literature Review., PMID:40430138
Effects of Hormone Replacement Treatment with Estrogen and Progestins on the Vascular Renin-Angiotensin System of Ovariectomized Rats., PMID:40430069
Host susceptibilities and entry processes of SARS-CoV-2 Omicron variants using pseudotyped viruses carrying spike protein., PMID:40426227
Using Machine Learning to Analyze Molecular Dynamics Simulations of Biomolecules., PMID:40423571
For research use only. Not for human or drug use.
