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Research Grade Erenumab (DHH31001)

Host species:Human
Isotype:IgG2-lambda
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHH31001

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG2-lambda

Clonality

Monoclonal

Target

CGRP type 1 receptor, CGRPR, Calcitonin receptor-like receptor, CALCRL, Calcitonin gene-related peptide type 1 receptor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q16602

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

AMG 334, erenumab-aooe, CAS: 1582205-90-0

Clone ID

Erenumab

Data Image
  • SDS-PAGE
    SDS PAGE for Erenumab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

A Controlled Trial of Erenumab for Episodic Migraine, PMID: 29171821

Erenumab in the treatment of migraine, PMID: 30235976

Erenumab-aooe, PMID: 30559520

ARISE: A Phase 3 randomized trial of erenumab for episodic migraine, PMID: 29471679

The role of erenumab in the treatment of migraine, PMID: 32523630

Safety and efficacy of erenumab for preventive treatment of chronic migraine: a randomised, double-blind, placebo-controlled phase 2 trial, PMID: 28460892

Erenumab for episodic migraine prophylaxis, PMID: 30614741

Vascular safety of erenumab for migraine prevention, PMID: 31852816

Erenumab in chronic migraine: Patient-reported outcomes in a randomized double-blind study, PMID: 30996060

Erenumab for migraine, PMID: 30670893

Erenumab: A First-in-Class Monoclonal Antibody for Migraine Prevention, PMID: 30813769

Erenumab safety and efficacy in migraine: A systematic review and meta-analysis of randomized clinical trials, PMID: 31876735

Erenumab: First Global Approval, PMID: 29968151

Early onset of efficacy with erenumab in patients with episodic and chronic migraine, PMID: 30276500

Real-World Patient Experience With Erenumab for the Preventive Treatment of Migraine, PMID: 32920850

Erenumab in chronic migraine with medication overuse: Subgroup analysis of a randomized trial, PMID: 30996056

Efficacy and safety of erenumab in women with a history of menstrual migraine, PMID: 32746775

Erenumab, PMID: 31643409

Nonclinical safety evaluation of erenumab, a CGRP receptor inhibitor for the prevention of migraine, PMID: 31085251

One-year sustained efficacy of erenumab in episodic migraine: Results of the STRIVE study, PMID: 32636324

Central effects of erenumab in migraine patients: An event-related functional imaging study, PMID: 32917805

Real-world effectiveness and tolerability of erenumab: A retrospective cohort study, PMID: 32791922

Efficacy and tolerability of erenumab in patients with episodic migraine in whom two-to-four previous preventive treatments were unsuccessful: a randomised, double-blind, placebo-controlled, phase 3b study, PMID: 30360965

Erenumab and galcanezumab in chronic migraine prevention: effects after treatment termination, PMID: 31159727

A Randomized Phase 2 Study of Erenumab for the Prevention of Episodic Migraine in Japanese Adults, PMID: 31612482

Erenumab, PMID: 30000991

Multidimensional assessment of the effects of erenumab in chronic migraine patients with previous unsuccessful preventive treatments: a comprehensive real-world experience, PMID: 32517693

Erenumab for Preventive Treatment of Migraine: A Systematic Review and Meta-Analysis of Efficacy and Safety, PMID: 30793254

In brief: Erenumab (Aimovig) hypersensitivity, PMID: 31022159

A prospective real-world analysis of erenumab in refractory chronic migraine, PMID: 32487102

Long-term safety and efficacy of erenumab in patients with chronic migraine: Results from a 52-week, open-label extension study, PMID: 32216456

Erenumab in Chronic Migraine: An Australian Experience, PMID: 32990364

Efficacy, tolerability, and safety of erenumab for the preventive treatment of persistent post-traumatic headache attributed to mild traumatic brain injury: an open-label study, PMID: 32493206

Migraine overview and summary of current and emerging treatment options, PMID: 30681821

Erenumab Side Effects, PMID: 31297805

Long-term efficacy and safety of erenumab in migraine prevention: Results from a 5-year, open-label treatment phase of a randomized clinical trial, PMID: 33400330

Erenumab-Induced Severe Nausea Leading to Smoking Cessation: A Retrospective Case Series, PMID: 33202039

Erenumab does not alter cerebral hemodynamics and endothelial function in migraine without aura, PMID: 32867533

Hypertension: A new safety risk for patients treated with erenumab, PMID: 33423274

Efficacy and safety of erenumab (AMG334) in chronic migraine patients with prior preventive treatment failure: A subgroup analysis of a randomized, double-blind, placebo-controlled study, PMID: 29984601

Erenumab During Breastfeeding, PMID: 31381367

Erenumab is effective in reducing migraine frequency and improving physical functioning, PMID: 30108057

Long-term safety and tolerability of erenumab: Three-plus year results from a five-year open-label extension study in episodic migraine, PMID: 31146544

Predicting erenumab adverse events with single-cell genomics, PMID: 32653068

Safety profile of erenumab, galcanezumab and fremanezumab in pregnancy and lactation: Analysis of the WHO pharmacovigilance database, PMID: 33435709

Pharmacoeconomic Review Report: Erenumab (Aimovig): (Novartis Pharmaceuticals Canada Inc.) [Internet], PMID: 33476110

Erenumab Efficacy on Comorbid Cluster Headache in Patients With Migraine: A Real-World Case Series, PMID: 32359106

Erenumab-aooe, Benralizumab, and Tezacaftor/ivacaftor, PMID: 30190109

Erenumab in Chronic Migraine Patients Who Previously Failed Five First-Line Oral Prophylactics and OnabotulinumtoxinA: A Dual-Center Retrospective Observational Study, PMID: 32547474

Clinical Review Report: Erenumab (Aimovig): (Novartis Pharmaceuticals Canada Inc.) [Internet], PMID: 33471453

Datasheet

Document Download

Research Grade Erenumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

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Research Grade Erenumab [DHH31001]
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