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Research Grade Capromab (DHG01303)

Host species:Mouse
Isotype:IgG1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHG01303

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Mouse

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

NAALAD1, Prostate-specific membrane antigen, NAALADase I, PSMA, PSM, Pteroylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase 2, N-acetylated-alpha-linked acidic dipeptidase I, Glutamate carboxypeptidase II, FOLH1, FGCP, FOLH, Folylpoly-gamma-glutamate carboxypeptidase, Folate hydrolase 1, GCPII, Membrane glutamate carboxypeptidase, Cell growth-inhibiting gene 27 protein, mGCP

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q04609

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

7E11-C5.3 radiolabelled, Indium In1111 ProstaScint, capromab pendetide, CAS: 145464-28-4

Clone ID

Capromab

Data Image
  • SDS-PAGE
    SDS PAGE for Capromab
References

Capromab Pendetide imaging of prostate cancer, PMID: 10803318

111 In-Capromab pendetide, PMID: 20641439

Capromab pendetide. A review of its use as an imaging agent in prostate cancer, PMID: 9571393

Utility of capromab pendetide (ProstaScint) imaging in the management of prostate cancer, PMID: 11272670

Indium-111 capromab pendetide in the management of recurrent prostate cancer, PMID: 18279057

Improved performance of SPECT-CT In-111 capromab pendetide by correlation with diffusion-weighted magnetic resonance imaging for identifying metastatic pelvic lymphadenopathy in prostate cancer, PMID: 23595605

Update on fused capromab pendetide imaging of prostate cancer, PMID: 15882479

Development of a 124I-labeled version of the anti-PSMA monoclonal antibody capromab for immunoPET staging of prostate cancer: Aspects of labeling chemistry and biodistribution, PMID: 24718894

Detection of recurrent prostate carcinoma with anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid PET/CT and 111In-capromab pendetide SPECT/CT, PMID: 21493787

Immunoscintigraphy with indium-111-capromab pendetide: evaluation before definitive therapy in patients with prostate cancer, PMID: 10604708

Clinical utility of indium 111-capromab pendetide immunoscintigraphy in the detection of early, recurrent prostate carcinoma after radical prostatectomy, PMID: 11920467

Diagnostic performance of In-111 capromab pendetide SPECT/CT in localized and metastatic prostate cancer, PMID: 21892036

Long-term follow-up of 111In-capromab pendetide (ProstaScint) scan as pretreatment assessment in patients who undergo salvage radiotherapy for rising prostate-specific antigen after radical prostatectomy for prostate cancer, PMID: 17293236

Evaluation of alternative methods for radiochemical purity testing of indium-111 capromab pendetide, PMID: 21555286

Image-guided radiotherapy for prostate cancer: a prospective trial of concomitant boost using indium-111-capromab pendetide (ProstaScint) imaging, PMID: 21477947

The role of (111)In Capromab Pendetide (Prosta-ScintR) immunoscintigraphy in the management of prostate cancer, PMID: 12114876

Indium-111-capromab pendetide scans: an important test relevant to clinical decision making, PMID: 11248605

Indium-111-capromab pendetide radioimmunoscintigraphy and prognosis for durable biochemical response to salvage radiation therapy in men after failed prostatectomy, PMID: 12721246

Current Clinical Applications of the In-capromab Pendetide Scan (ProstaScint(R) Scan, Cyt-356), PMID: 16985714

Anti-3-[(18)F]FACBC positron emission tomography-computerized tomography and (111)In-capromab pendetide single photon emission computerized tomography-computerized tomography for recurrent prostate carcinoma: results of a prospective clinical trial, PMID: 24144687

111-In-capromab pendetide imaging using hybrid-γ camera-computer tomography technology is not reliable in detecting seminal vesicle invasion in patients with prostate cancer, PMID: 20189846

Prostate-specific membrane antigen-based imaging, PMID: 22658884

Use of local (111)in-capromab pendetide scan results to predict outcome after salvage radiotherapy for prostate cancer, PMID: 18164863

Ten-year outcomes: the clinical utility of single photon emission computed tomography/computed tomography capromab pendetide (Prostascint) in a cohort diagnosed with localized prostate cancer, PMID: 20961696

Editorial comment, PMID: 19616227

In vivo tumor grading of prostate cancer using quantitative 111In-capromab pendetide SPECT/CT, PMID: 20008977

111In-capromab pendetide: the evolution of prostate specific membrane antigen and the nuclear imaging of its 111In-labelled murine antibody in the evaluation of prostate cancer, PMID: 18034550

Technology insight: monoclonal antibody imaging of prostate cancer, PMID: 16607370

A phase II study of [90Y] yttrium-capromab pendetide in the treatment of men with prostate cancer recurrence following radical prostatectomy, PMID: 10850293

Prostate cancer abdominal metastases detected with indium-111 capromab pendetide, PMID: 9544673

Use of 111in-capromab pendetide immunoscintigraphy to image localized prostate cancer foci within the prostate gland, PMID: 19616259

Salvage cryosurgical ablation of the prostate for local recurrence after radiation therapy: improved outcomes utilizing a capromab pendetide scan and biopsy algorithm, PMID: 18163941

Detection of Recurrent Non-Hodgkin Lymphoma on In-111 Capromab Pendetide Imaging, PMID: 25899589

Single photon emission computerized tomography with capromab pendetide plus computerized tomography image set co-registration independently predicts biochemical failure, PMID: 18343445

123 I-Labeled (S)-2-(3-((S)-1-carboxy-5-(4-iodobenzylamino)pentyl)ureido)pentanedoic acid, PMID: 20641935

Indium-111 capromab pendetide (ProstaScint) imaging to detect recurrent and metastatic prostate cancer, PMID: 9790041

Indium-111 Capromab Pendetide (ProstaScint(®)) Demonstrates Renal Cell Carcinoma and Aortocaval Nodal Metastases from Prostate Adenocarcinoma, PMID: 26420994

Utilization of (111)In-Capromab pendetide SPECT-CT for detecting seminal vesicle invasion with recurrent prostate cancer after primary in situ therapy, PMID: 19843189

123 I-Labeled (S)-2-(3-((S)-1-carboxy-5-(3-(4-iodophenyl) ureido)pentyl)ureido)pentanedoic acid, PMID: 20641856

Imaging of prostate cancer, PMID: 17157630

111Indium-capromab pendetide in the evaluation of patients with residual or recurrent prostate cancer after radical prostatectomy. The ProstaScint Study Group, PMID: 9598514

Prostate specific membrane antigen (PSMA) ligands for diagnosis and therapy of prostate cancer, PMID: 27679869

Therapy with immunoglobulin: applications for monoclonal antibodies, PMID: 16878853

Capromab Pendetide immunoscintigraphy: connecting the dots for prostate cancer imaging, PMID: 10803317

Disposable bioreactors: maturation into pharmaceutical glycoprotein manufacturing, PMID: 19517075

Technical considerations for acquiring and processing indium-111 capromab pendetide images, PMID: 9291068

ProstaScint and its role in the diagnosis of prostate cancer, PMID: 17620043

Capromab pendetide scanning has a potential role in optimizing patient selection for salvage cryosurgical ablation of the prostate, PMID: 20434196

Progress in SPECT/CT imaging of prostate cancer, PMID: 16866563

Biochemical disease-free survival rates following definitive low-dose-rate prostate brachytherapy with dose escalation to biologic target volumes identified with SPECT/CT capromab pendetide, PMID: 17284381

Datasheet

Document Download

Research Grade Capromab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Capromab [DHG01303]
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