Catalog No.
DXX00501
Expression system
Mammalian Cells
Species reactivity
Escherichia coli
Host species
Humanized
Isotype
IgG1-kappa
Clonality
Monoclonal
Target
shiga toxin type 2stx2B
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q07871
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
HuVTm1.1, TMA-15, CAS: 502496-16-4
Clone ID
Urtoxazumab
Efficacy of Urtoxazumab (TMA-15 Humanized Monoclonal Antibody Specific for Shiga Toxin 2) Against Post-Diarrheal Neurological Sequelae Caused by Escherichia coli O157:H7 Infection in the Neonatal Gnotobiotic Piglet Model, PMID: 28134751
Safety and pharmacokinetics of urtoxazumab, a humanized monoclonal antibody, against Shiga-like toxin 2 in healthy adults and in pediatric patients infected with Shiga-like toxin-producing Escherichia coli, PMID: 19822704
Interventions for preventing diarrhoea-associated haemolytic uraemic syndrome, PMID: 34219224
Gateways to clinical trials, PMID: 20664824
Pathophysiology and treatment of typical and atypical hemolytic uremic syndrome, PMID: 25845294
Efficacy of postinfection treatment with anti-Shiga toxin (Stx) 2 humanized monoclonal antibody TMA-15 in mice lethally challenged with Stx-producing Escherichia coli, PMID: 11517435
Role of Shiga toxin 2 (Stx2)-binding protein, human serum amyloid P component (HuSAP), in Shiga toxin-producing Escherichia coli infections: assumption from in vitro and in vivo study using HuSAP and anti-Stx2 humanized monoclonal antibody TMA-15, PMID: 12767937
For research use only. Not for human or drug use.
