Research Grade Metelimumab (DHB91602)

Catalog No.

DHB91602

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG4-kappa

Clonality

Monoclonal

Target

Transforming growth factor beta-1 proprotein, LAP, TGF-beta-1, TGFB1, TGFB

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01137

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

CAT-192, CAS: 272780-74-2

Clone ID

Metelimumab

Gateways to clinical trials, PMID: 15672123

Gateways to clinical trials, PMID: 15834452

Novel use of accelerator mass spectrometry for the quantification of low levels of systemic therapeutic recombinant protein, PMID: 16554138

Strategies for TGF-beta modulation: a review of recent patents, PMID: 19939191

Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGFβ1 antibody, PMID: 29333938

Document Download

Research Grade Metelimumab.pdf