Catalog No.
YHF13501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala21-Ala89
Predicted molecular weight
10.15 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P55774
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PARC, AMAC1, DC-CK1, MIP4, CC chemokine PARC, Pulmonary and activation-regulated chemokine, DCCK1, Alternative macrophage activation-associated CC chemokine 1, MIP-4, Macrophage inflammatory protein 4, Small-inducible cytokine A18, Dendritic cell chemokine 1, C-C motif chemokine 18, CCL18, SCYA18, AMAC-1
Increased CCL18 expression infers a poor prognosis in glioblastoma multiforme and promotes U-87 MG cell proliferation and migration: A retrospective cohort study., PMID:40441238
Characteristic genes and immune landscape of interstitial cystitis., PMID:40435311
M2 macrophages activate the IL-10/JAK2/STAT3 pathway to induce pathological microangiogenesis in the nucleus pulposus exacerbating intervertebral disc degeneration., PMID:40426248
Deciphering the Connection Between Atopic Dermatitis and Cardiovascular Diseases: Analysis of Clinical Associations and Cardiometabolic Proteins., PMID:40386898
Complementary Analysis of Local and Systemic Effects of Dupilumab in Paediatric AD Using Tape Strips and Serum., PMID:40375583
Insights into interstitial lung disease pathogenesis., PMID:40365095
CCL18 derived from M2-polarized tumor-associated macrophages promotes endometrial cancer progression by activating the TWIST1/HMGA1 axis., PMID:40353623
Blocking of IL-4/IL-13 Signalling With Dupilumab Results in Restoration of Serum and Cutaneous Abnormalities in Netherton Syndrome., PMID:40344324
m6A reader IGF2BP1 facilitates macrophage glycolytic metabolism and fibrotic phenotype by stabilizing THBS1 mRNA to promote pulmonary fibrosis., PMID:40220148
The CD163 + tissue-infiltrating macrophages regulate ferroptosis in thyroid-associated ophthalmopathy orbital fibroblasts via the TGF-β/Smad2/3 signaling pathway., PMID:40211281
Advances and future outlook in clinical trials for treating systemic sclerosis-interstitial lung disease., PMID:40197088
Artesunate Suppresses the Migration and Invasion of Thyroid Cancer Cells via Upregulating PTEN to Block M2 Polarization of Tumor-Associated Macrophages., PMID:40103302
ZEB1 promotes the immune escape of ovarian cancer through the MCSF-CCL18 axis., PMID:40089803
Nutrients Lowering Obesity-Linked Chemokines Blamable for Metastasis., PMID:40076892
Neutrophil extracellular traps and macrophage activation contibute to thrombosis and post-covid syndrome in SARS-CoV-2 infection., PMID:40066452
CC-chemokine ligand 18, CXC motif chemokine 13 and osteopontin as biomarkers of silicosis and asbestosis: a prospective observational study., PMID:40000810
Dissecting the Spatial and Single-Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer., PMID:39950944
Real-World Efficacy and Safety of Abrocitinib in Chinese Atopic Dermatitis Patients: A Single-Center Prospective Study., PMID:39927851
Pre-Treatment MMP7 Predicts Progressive Idiopathic Pulmonary Fibrosis in Antifibrotic Treated Patients., PMID:39919729
Chemokine Expression in Well-Differentiated Liposarcoma May Be Involved in the Tumorigenesis of Lymphoplasmacytic Lymphoma: A Case Study., PMID:39894788
The immune microenvironment related biomarker CCL18 for patients with gout by comprehensive analysis., PMID:39752850
Treatment Response Biomarkers for Systemic Sclerosis-Associated Interstitial Lung Disease., PMID:39711034
Bioinformatics analysis reveals potential crosstalk genes and molecular mechanisms between ulcerative colitis and psoriasis., PMID:39673621
Tralokinumab Treatment in Adult Atopic Dermatitis Patients: 28-Week Evaluation of Clinical Effectiveness, Safety, Serum Proteins and Total IgE Levels., PMID:39673366
Identification of hub genes in the crosstalk between type 2 diabetic nephropathy and obesity according to bioinformatics analysis., PMID:39526504
Biomarkers associated with papillary thyroid carcinoma and Hashimoto's thyroiditis: Bioinformatic analysis and experimental validation., PMID:39510033
EDNRA affects susceptibility to large artery atherosclerosis stroke through potential inflammatory pathway., PMID:39448657
Acute and chronic impact of interleukin-33 stimulation on chemokines and growth factors in human cord blood-derived mast cells., PMID:39432538
Serum inflammatory biomarkers associated with disease severity and response to dupilumab treatment in bullous pemphigoid: A cluster analysis., PMID:39358056
The chemokine receptor CCR8 is not a high-affinity receptor for the human chemokine CCL18., PMID:39259753
Cord Blood Serum Levels of IL-31 and CCL17, Cutaneous Markers, and Development of Atopic Dermatitis., PMID:39259556
Inhibition of STAT3 by 2-Methoxyestradiol suppresses M2 polarization and protumoral functions of macrophages in breast cancer., PMID:39256694
C-C Motif Ligand 7 and C-C Motif Chemokine Receptor 3 Dysregulation in Patients With Scrub Typhus and Association With Mortality., PMID:39190223
Multiomic profiling of new-onset kidney function decline: insights from the STANISLAS study cohort with a 20-year follow-up., PMID:39135941
Biomarker Changes in Response to Tofacitinib Treatment in Patients With Polyarticular-Course Juvenile Idiopathic Arthritis., PMID:39135452
CCL18 promotes endometriosis by increasing endometrial cell migration and neuroangiogenesis., PMID:39105608
Comprehensive analysis of miRNAs-lncRNAs-mRNAs modules and ceRNA network in acute liver failure: Hsa-miR3175 and C-reactive protein determination., PMID:39029818
Lactate activates CCL18 expression via H3K18 lactylation in macrophages to promote tumorigenesis of ovarian cancer., PMID:39010846
MMP9 and CCL18 associate with chronic urticaria while type I, IV, and VI collagens change with omalizumab treatment., PMID:38953463
Effects of Active Chronic Cigarette-Smoke Exposure on Circulating Fibrocytes., PMID:38935158
CHIT1 at diagnosis predicts faster disability progression and reflects early microglial activation in multiple sclerosis., PMID:38866782
Epidermal growth factor receptor/mitogen-activated kinase inhibitor treatment induces a distinct inflammatory hair follicle response that includes collapse of immune privilege., PMID:38857906
Immunological Roles of CCL18 in Pan‑Cancer and Its Potential Value in Endometrial Cancer., PMID:38816548
CCL18 aggravates atherosclerosis by inducing CCR6-dependent T-cell influx and polarization., PMID:38807599
ACE Phenotyping in Human Blood and Tissues: Revelation of ACE Outliers and Sex Differences in ACE Sialylation., PMID:38790902
Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry., PMID:38753183
Single-Cell Profiling Reveals Immune Aberrations in Progressive Idiopathic Pulmonary Fibrosis., PMID:38717443
The Expression and Secretion Profile of TRAP5 Isoforms in Gaucher Disease., PMID:38667330
Targeted plasma proteomic analysis uncovers a high-performance biomarker panel for early diagnosis of gastric cancer., PMID:38631604
Relationship between chemokine/chemokine receptor and glioma prognosis and outcomes: Systematic review and meta-analysis., PMID:38631221
For research use only. Not for human or drug use.
