Catalog No.
YVV01101
Expression system
E. coli
Species
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Protein length
Ala181-Gly818
Predicted molecular weight
72.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P0DTD1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Non-structural protein 2, nsp2, p65 homolog, Replicase polyprotein 1ab, pp1ab, ORF1ab polyprotein
SARS-COV-2 mutations in North Rift, Kenya., PMID:40478857
SARS-CoV-2 NSP2 specifically interacts with cellular protein SmgGDS., PMID:40253909
Differential clearance rate of proteins encoded on a self-amplifying mRNA COVID-19 vaccine in muscle and lymph nodes., PMID:40236291
A comprehensive review of current insights into the virulence factors of SARS-CoV-2., PMID:39878471
MDA5 Is a Major Determinant of Developing Symptoms in Critically Ill COVID-19 Patients., PMID:39460899
Honeysuckle-Derived miR2911 Inhibits Replication of Porcine Reproductive and Respiratory Syndrome Virus by Targeting Viral Gene Regions., PMID:39339827
The glycoprotein quality control factor Malectin promotes coronavirus replication and viral protein biogenesis., PMID:38895409
An entropy-based study on the mutational landscape of SARS-CoV-2 in USA: Comparing different variants and revealing co-mutational behavior of proteins., PMID:38754568
Characteristics of SARS-CoV-2 Omicron BA.5 variants in Shanghai after ending the zero-COVID policy in December 2022: a clinical and genomic analysis., PMID:38605705
SARS-CoV-2 NSP2 as a Potential Delivery Vehicle for Proteins., PMID:38288708
In Silico Analysis of SARS-CoV-2 Non-Structural Proteins Reveals an Interaction with the Host's Heat Shock Proteins That May Contribute to Viral Replications and Development., PMID:38132484
Novel Mutations in the Non-Structure Protein 2 of SARS-CoV-2., PMID:38028396
Tracking the Selective Pressure Profile and Gene Flow of SARS-CoV-2 Delta Variant in Italy from April to October 2021 and Frequencies of Key Mutations from Three Representative Italian Regions., PMID:38004656
Discovery and development of COVID-19 vaccine from laboratory to clinic., PMID:37953736
Emergence of SARS-CoV-2 variant of interest B.1.525 (Eta) in Bangladesh., PMID:37804694
On-chip screening of SARS-CoV-2 cDNA by LAMP-integrated rotational diffusometry., PMID:37776805
The SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression., PMID:37732428
Toehold switch plus signal amplification enables rapid detection., PMID:37641181
Identification of a 1.4-kb-Long Sequence Located in the nsp12 and nsp13 Coding Regions of SARS-CoV-2 Genomic RNA That Mediates Efficient Viral RNA Packaging., PMID:37367225
Mechanisms of impairment of interferon production by SARS-CoV-2., PMID:37199495
Prolonged infective SARS-CoV-2 omicron variant shedding in a patient with diffuse large B cell lymphoma successfully cleared after three courses of remdesivir., PMID:37182841
SARS-CoV-2 viral protein Nsp2 stimulates translation under normal and hypoxic conditions., PMID:36998012
Dissecting Phenotype from Genotype with Clinical Isolates of SARS-CoV-2 First Wave Variants., PMID:36992320
Automated SSHHPS Analysis Predicts a Potential Host Protein Target Common to Several Neuroinvasive (+)ssRNA Viruses., PMID:36851756
SARS-CoV-2 Nsp2 Contributes to Inflammation by Activating NF-κB., PMID:36851549
Protein expression/secretion boost by a novel unique 21-mer cis-regulatory motif (Exin21) via mRNA stabilization., PMID:36793212
Genomic Analysis of Non-B Nucleic Acids Structures in SARS-CoV-2: Potential Key Roles for These Structures in Mutability, Translation, and Replication?, PMID:36672896
Genomic landscape of alpha-variant of SARS-CoV-2 circulated in Pakistan., PMID:36512569
Insights into the Dynamics and Binding of Two Polyprotein Substrate Cleavage Points in the Context of the SARS-CoV-2 Main and Papain-like Proteases., PMID:36500348
Insight into SARS-CoV-2 Omicron variants in Saudi Arabian genomic isolates., PMID:36379532
Molecular Dynamics Simulations to Decipher the Role of Phosphorylation of SARS-CoV-2 Nonstructural Proteins (nsps) in Viral Replication., PMID:36366534
Genetic Recombination Sites Away from the Insertion/Deletion Hotspots in SARS-Related Coronaviruses., PMID:36351613
Determination of binding affinity of tunicamycin with SARS-CoV-2 proteins: Proteinase, protease, nsp2, nsp9, ORF3a, ORF7a, ORF8, ORF9b, envelope and RBD of spike glycoprotein., PMID:36349218
Insertion/deletion hotspots in the Nsp2, Nsp3, S1, and ORF8 genes of SARS-related coronaviruses., PMID:36307763
Time Series Analysis of SARS-CoV-2 Genomes and Correlations among Highly Prevalent Mutations., PMID:36069583
Genetically Encoded Fluorescent Sensors for SARS-CoV-2 Papain-like Protease PLpro., PMID:35887174
SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation., PMID:35878012
The SARS-CoV-2 protein NSP2 impairs the silencing capacity of the human 4EHP-GIGYF2 complex., PMID:35756894
Expression Profile and Localization of SARS-CoV-2 Nonstructural Replicase Proteins in Infected Cells., PMID:35730969
Altered Lipid Profile in COVID-19 Patients and Metabolic Reprogramming., PMID:35633693
Geographical distribution of SARS-CoV-2 amino acids mutations and the concomitant evolution of seven distinct clades in non-human hosts., PMID:35614572
Lebanese SARS-CoV-2 genomics: 24 months of the pandemic., PMID:35605880
Inhibition of the IFN-α JAK/STAT Pathway by MERS-CoV and SARS-CoV-1 Proteins in Human Epithelial Cells., PMID:35458397
Effects of theaflavin-gallate in-silico binding with different proteins of SARS-CoV-2 and host inflammation and vasoregulations referring an experimental rat-lung injury., PMID:35403090
Partial sequence conservation of SARS-CoV-2 NSP-2, NSP-12, and Spike in stool samples from Abadan, Iran., PMID:35396867
In silico anti-SARS-CoV-2 activities of five-membered heterocycle-substituted benzimidazoles., PMID:35340531
Computational Analysis Reveals Monomethylated Triazolopyrimidine as a Novel Inhibitor of SARS-CoV-2 RNA-Dependent RNA Polymerase (RdRp)., PMID:35164069
Immunoinformatics prediction of potential immunodominant epitopes from human coronaviruses and association with autoimmunity., PMID:35006282
A benzimidazole scaffold as a promising inhibitor against SARS-CoV-2., PMID:35000553
Palindromic target site identification in SARS-CoV-2, MERS-CoV and SARS-CoV-1 by adopting CRISPR-Cas technique., PMID:34999179
For research use only. Not for human or drug use.
