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Research Grade Refanezumab (DHD43401)

Host species:Humanized
Isotype:IgG1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHD43401

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

Myelin-associated glycoprotein, MAG, Siglec-4a, GMA

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P20916

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

GSK-249320, CAS: 1233953-61-1

Clone ID

Refanezumab

Data Image
  • SDS-PAGE
    SDS PAGE for Refanezumab
References

Proof-of-Concept Randomized Trial of the Monoclonal Antibody GSK249320 Versus Placebo in Stroke Patients, PMID: 28228578

First-time-in-human study with GSK249320, a myelin-associated glycoprotein inhibitor, in healthy volunteers, PMID: 23267856

Safety, pharmacokinetics, and pharmacodynamics of escalating repeat doses of GSK249320 in patients with stroke, PMID: 23471268

Effects of postinfarct myelin-associated glycoprotein antibody treatment on motor recovery and motor map plasticity in squirrel monkeys, PMID: 25931462

Datasheet

Document Download

Research Grade Refanezumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Refanezumab [DHD43401]
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