Catalog No.
YHJ48501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu20-Thr220
Predicted molecular weight
24.97 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BQ51
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PDCD1 ligand 2, B7-DC, PD-L2, PDCD1LG2, PDCD1L2, PDL2, Butyrophilin B7-DC, Programmed death ligand 2, Programmed cell death 1 ligand 2, CD273, B7DC, PD-1 ligand 2
CD9/SOX2-positive cells in the intermediate lobe of the rat pituitary gland exhibit mesenchymal stem cell characteristics., PMID:39808267
Phenotypic characterization of disease-initiating stem cells in JAK2- or CALR-mutated myeloproliferative neoplasms., PMID:36814396
Transformation of FL into DLBCL with a PMBL gene expression signature., PMID:36240289
Inhibitors of the Actin-Bundling Protein Fascin-1 Developed for Tumor Therapy Attenuate the T-Cell Stimulatory Properties of Dendritic Cells., PMID:35681718
The generation of PD-L1 and PD-L2 in cancer cells: From nuclear chromatin reorganization to extracellular presentation., PMID:35530130
Detrimental Effect of Trypanosoma brucei brucei Infection on Memory B Cells and Host Ability to Recall Protective B-cell Responses., PMID:35363871
The Positive and Negative Immunoregulatory Role of B7 Family: Promising Novel Targets in Gastric Cancer Treatment., PMID:34639059
Epicutaneous Administration of 17β-Estradiol Induces Langerhans Cells Depletion., PMID:34569394
The PD-1 Interactome., PMID:34170628
PD-1, PD-L1, and PD-L2 Gene Expression and Tumor Infiltrating Lymphocytes in Canine Melanoma., PMID:34169800
Fucosylation and Sialylation of Fc-Fragment of anti-Tumour Necrosis Factor Alpha Antibodies do not Influence Their Immunogenicity in Monocyte-Derived Dendritic Cells., PMID:33631789
Peptide Blocking CTLA-4 and B7-1 Interaction., PMID:33419027
Retinal Pigment Epithelial Cells Derived from Induced Pluripotent Stem (iPS) Cells Suppress or Activate T Cells via Costimulatory Signals., PMID:32899567
CD279 mediates the homeostasis and survival of regulatory T cells by enhancing T cell and macrophage interactions., PMID:32324337
A Tumor-Specific Super-Enhancer Drives Immune Evasion by Guiding Synchronous Expression of PD-L1 and PD-L2., PMID:31825827
miR29a and miR378b Influence CpG-Stimulated Dendritic Cells and Regulate cGAS/STING Pathway., PMID:31779082
Toxicity of silver nanoparticles in mouse bone marrow-derived dendritic cells: Implications for phenotype., PMID:30938211
High frequency of macrophages expressing elevated level of CD80, PD-Ls and TLR1 in nasal polyps of CRS patients., PMID:30528981
Reversal of Triple-Negative Breast Cancer EMT by miR-200c Decreases Tryptophan Catabolism and a Program of Immunosuppression., PMID:30213797
Proteomic Profiling of Native Unpassaged and Culture-Expanded Mesenchymal Stromal Cells (MSC)., PMID:30211967
A role for B cells in organic dust induced lung inflammation., PMID:29273051
Tumor PDCD1LG2 (PD-L2) Expression and the Lymphocytic Reaction to Colorectal Cancer., PMID:29038297
CD73 expression identifies a subset of IgM+ antigen-experienced cells with memory attributes that is T cell and CD40 signalling dependent., PMID:28746783
PD-1 function in apoptosis of T lymphocytes in canine visceral leishmaniasis., PMID:27016050
Cutting Edge: CTLA-4Ig Inhibits Memory B Cell Responses and Promotes Allograft Survival in Sensitized Recipients., PMID:26416270
What Makes Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells Superior Immunomodulators When Compared to Bone Marrow Derived Mesenchymal Stromal Cells?, PMID:26064137
PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment., PMID:25349132
Human Chorionic Villous Mesenchymal Stem Cells Modify the Functions of Human Dendritic Cells, and Induce an Anti-Inflammatory Phenotype in CD1+ Dendritic Cells., PMID:25287760
Biochemical signaling of PD-1 on T cells and its functional implications., PMID:25098287
The PD-1/PD-Ls pathway and autoimmune diseases., PMID:24908630
Dental pulp dendritic cells migrate to regional lymph nodes., PMID:24378366
Human placental mesenchymal stem cells (pMSCs) play a role as immune suppressive cells by shifting macrophage differentiation from inflammatory M1 to anti-inflammatory M2 macrophages., PMID:23812784
Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer., PMID:23460533
The role of B7 family molecules in hematologic malignancy., PMID:23223433
Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection., PMID:22308386
Aging-associated B7-DC+ B cells enhance anti-tumor immunity via Th1 and Th17 induction., PMID:22044484
Differential expression of co-signal molecules and migratory properties in four distinct subsets of migratory dendritic cells from the oral mucosa., PMID:21893045
Functional and phenotypic characteristics of alternative activation induced in human monocytes by interleukin-4 or the parasitic nematode Brugia malayi., PMID:21788379
MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers., PMID:21368758
L2pB1: a new player in autoimmunity., PMID:21195478
Cutting edge: Hierarchy of maturity of murine memory B cell subsets., PMID:21078902
New monoclonal antibodies against B-cell antigens: possible new strategies for diagnosis of primary cutaneous B-cell lymphomas., PMID:20951741
Stromal cells' B7-1 is a key stimulatory molecule for interleukin-10 production by HOZOT, a multifunctional regulatory T-cell line., PMID:20628373
Renal tubular PD-L1 (CD274) suppresses alloreactive human T-cell responses., PMID:20393451
B7-H1 on myeloid-derived suppressor cells in immune suppression by a mouse model of ovarian cancer., PMID:18790673
Airway epithelial cells modify immune responses by inducing an anti-inflammatory microenvironment., PMID:18421791
Monocyte-derived dendritic cells in multiple sclerosis: the effect of bacterial infection., PMID:17936916
"Alternatively activated" dendritic cells preferentially secrete IL-10, expand Foxp3+CD4+ T cells, and induce long-term organ allograft survival in combination with CTLA4-Ig., PMID:17056511
Migratory Langerhans cells in mouse lymph nodes in steady state and inflammation., PMID:15982311
For research use only. Not for human or drug use.
