Research Grade Volagidemab

Catalog No.

DHE51801

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG2-kappa

Clonality

Monoclonal

Target

GCGR, Glucagon receptor, GL-R

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P47871

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

AMG 477, REMD-477, CAS: 1233956-13-2

Clone ID

Volagidemab

Efficacy and safety of the glucagon receptor antagonist volagidemab in type-1 diabetes: A systematic review and meta-analysis., PMID:39625039

Combination SGLT2 Inhibitor and Glucagon Receptor Antagonist Therapy in Type 1 Diabetes: A Randomized Clinical Trial., PMID:38776437

Emerging Anti-Diabetic Drugs for Beta-Cell Protection in Type 1 Diabetes., PMID:37296593

Publisher Correction: Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial., PMID:36932248

Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial., PMID:36192552

Effect of a glucagon receptor antibody (REMD-477) in type 1 diabetes: A randomized controlled trial., PMID:29283470

Document Download

Research Grade Volagidemab.pdf