Catalog No.
YHJ19801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val26-Val200
Predicted molecular weight
22.05 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8IZJ0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IFNL2, IFN-lambda-2, IL-28A, IL28A, Interferon lambda-2, Cytokine Zcyto20, Interleukin-28A, ZCYTO20
Elevated serum levels of IL-10 family and IL-12 family cytokines in myasthenia gravis., PMID:40288071
The Factors Associated with the Blood-Brain Barrier Dysfunction in Tick-Borne Encephalitis., PMID:40003967
Comparative analysis of salivary cytokine profiles and oral microbial composition in caries-active and caries-free children., PMID:39921084
Exploring the Involvement of New Members of the Interleukin Family in Cardiovascular Disease., PMID:39844544
Potential therapeutic effects of IL28RA inhibition on acute myocardial infarction through phosphorylated JAK1/STAT1 signaling pathways., PMID:39706854
Higher Intraocular Levels of Inflammatory Factors are Related to Retinal Vascular and Neurodegeneration in Myopic Retinopathy., PMID:39677296
Interferon regulatory factor 7 alleviates the experimental colitis through enhancing IL-28A-mediated intestinal epithelial integrity., PMID:39370517
IL-28A/IL-10Rβ axis promotes angiogenesis via eNOS/AKT signaling and AP-1/NF-κB/MMP-2 network by regulating HSP70-1 expression., PMID:39127098
Reduced IFNL1 and/or IFNL2, but not IFNL3 is associated with worse outcome in patients with COVID-19., PMID:38953458
The Identification and Function of Linc01615 on Influenza Virus Infection and Antiviral Response., PMID:38928290
CSF levels of Chitinase3like1 correlate with early response to cladribine in multiple sclerosis., PMID:38404586
Interleukin 28A aggravates Con A-induced acute liver injury by promoting the recruitment of M1 macrophages., PMID:38265281
27-hydroxycholesterol causes cognitive deficits by disturbing Th17/Treg balance and the related immune responses in mild cognitive impairment patients and C57BL/6J mice., PMID:38115100
Maternal di-(2-ethylhexyl) phthalate exposure elicits offspring IFN-λ upregulation: Insights from birth cohort, murine model, and in vitro mechanistic analysis., PMID:37611859
Serum cytokine profiling reveals different immune response patterns during general and severe Mycoplasma pneumoniae pneumonia., PMID:36618370
Lower level of IL-28A as a predictive index of the artificial liver support system in effective treatment of patients with HBV-ACLF., PMID:36336888
Assessment of serum interleukin-28 as a biomarker to predict mortality in traumatic patients with sepsis., PMID:35816926
Immunomodulatory effect of a very-low-calorie ketogenic diet compared with bariatric surgery and a low-calorie diet in patients with excessive body weight., PMID:35667273
Interleukin-10 family members: Biology and role in the bone and joint diseases., PMID:35623292
Elevated IL-19 Serum Levels in Patients With Pernicious Anemia and Autoimmune Gastritis., PMID:35479078
Isarubrolone C Promotes Autophagic Degradation of Virus Proteins via Activating ATG10S in HepG2 Cells., PMID:35201775
Cyclic pressure-induced cytokines from gingival fibroblasts stimulate osteoclast activity: Clinical implications for alveolar bone loss in denture wearers., PMID:35185110
Murine Type III interferons are functionally redundant and correlate with bacterial burden during influenza/bacterial super-infection., PMID:34618816
Pilot Study Analysis of Serum Cytokines to Differentiate Pediatric Septic Arthritis and Transient Synovitis., PMID:34483309
Serum Th17 and TNF-α distinguish between patients with occult hepatitis B infection, chronic hepatitis B infection and healthy individuals., PMID:34369380
Posttreatment Downregulation of Type III Interferons in Patients with Acute Brucellosis., PMID:34335092
BCG vaccination induces enhanced frequencies of dendritic cells and altered plasma levels of type I and type III interferons in elderly individuals., PMID:34302964
Chemokine/Cytokine Levels Correlate with Organ Involvement in PR3-ANCA-Associated Vasculitis., PMID:34205404
Role of IFNLR1 gene in PRRSV infection of PAM cells., PMID:34056880
Interleukin-28A maintains the intestinal epithelial barrier function through regulation of claudin-1., PMID:33842586
Are neutrophil extracellular traps the link for the cross-talk between periodontitis and rheumatoid arthritis physiopathology?, PMID:33752229
The role of interleukin-10 family members in cardiovascular diseases., PMID:33662690
Interleukin-28A induces epithelial barrier dysfunction in CD patient-derived intestinal organoids., PMID:33595362
Inhibition of Type III Interferon Expression in Intestinal Epithelial Cells-A Strategy Used by Coxsackie B Virus to Evade the Host's Innate Immune Response at the Primary Site of Infection?, PMID:33466313
The Dramatic Role of IFN Family in Aberrant Inflammatory Osteolysis., PMID:33245272
Based on G-Series Mouse TH17 Array Study the Effect of Fluoride on C2C12 Cells Cytokines Expression., PMID:33244669
IL-10 and Its Related Superfamily Members IL-19 and IL-24 Provide Parallel/Redundant Immune-Modulation in Loa loa Infection., PMID:32561912
Interleukin-29 and interleukin-28A induce migration of neutrophils in rheumatoid arthritis., PMID:32557259
Chip-based serum proteomics approach to reveal the potential protein markers in the sub-acute stroke patients receiving the treatment of Ginkgo Diterpene Lactone Meglumine Injection., PMID:32413576
Rhinovirus Infection Is Associated With Airway Epithelial Cell Necrosis and Inflammation via Interleukin-1 in Young Children With Cystic Fibrosis., PMID:32328066
IL28A protein homotetramer structure is required for autolysosomal degradation of HCV-NS5A in vitro., PMID:32205851
Disruption of Type III Interferon (IFN) Genes Ifnl2 and Ifnl3 Recapitulates Loss of the Type III IFN Receptor in the Mucosal Antiviral Response., PMID:31462571
IFN-λ Decreases Murid Herpesvirus-4 Infection of the Olfactory Epithelium but Fails to Prevent Virus Reactivation in the Vaginal Mucosa., PMID:31426334
Toll-Like Receptor 3 Deficiency Leads to Altered Immune Responses to Chlamydia trachomatis Infection in Human Oviduct Epithelial Cells., PMID:31383744
Interleukin 28 is a potential therapeutic target for sepsis., PMID:31121287
Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin., PMID:30886417
Expression of interleukin (IL)-10 family cytokines in aqueous humour of patients with specific endogenous uveitic entities: elevated levels of IL-19 in human leucocyte antigen-B27-associated uveitis., PMID:30761764
Regeneration After Radiation- and Immune-Mediated Tissue Injury Is Not Enhanced by Type III Interferon Signaling., PMID:30503785
Type III Interferons in Viral Infection and Antiviral Immunity., PMID:30439714
Interleukin 28A.rs12980602 and interleukin 28B.rs8103142 genotypes could be protective against HCV infection among Egyptians., PMID:30402710
For research use only. Not for human or drug use.
