Catalog No.
YHJ19701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val22-Val196
Predicted molecular weight
21.93 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8IZI9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IFNL3, IL28B, Interferon lambda-3, IL28C, IFN-lambda-3, Interleukin-28B, Interleukin-28C, Cytokine Zcyto22, IL-28B, ZCYTO22, IL-28C
Type III interferon, age and IFNL gene single nucleotide polymorphisms determine the characteristics of H1N1 influenza infection., PMID:40438107
Association Between IL-28B (rs8099917) and IL-28B (rs12979860) with Predisposition to Diseases Related to the HTLV-1: Systematic Review and Meta-Analysis., PMID:40430790
Exploring the impact of graded alcohol use on atherogenic lipid profiles among Latinos with underlying chronic liver disease., PMID:40022301
Enhancement of immune responses to classical swine fever virus E2 in mice by fusion or mixture with the porcine IL-28B., PMID:39945936
Exploring the Involvement of New Members of the Interleukin Family in Cardiovascular Disease., PMID:39844544
Augmented immunogenicity of the HPV16 DNA vaccine via dual adjuvant approach: integration of CpG ODN into plasmid backbone and co-administration with IL-28B gene adjuvant., PMID:39780219
Potential therapeutic effects of IL28RA inhibition on acute myocardial infarction through phosphorylated JAK1/STAT1 signaling pathways., PMID:39706854
Development of a genotype-matched Newcastle disease DNA vaccine candidate adjuvanted with IL-28b for the control of targeted velogenic strains of Newcastle disease virus in Africa., PMID:39585481
Efficacy of doxorubicin and lipiodol therapy by trans-arterial chemoembolization in hepatocellular carcinoma Egyptian patients and relation to genetic polymorphisms., PMID:39138591
Effect of immunogenetics polymorphism and expression on direct-acting antiviral drug response in chronic hepatitis C., PMID:39117877
Identification of CXCL9 chemokine as a potential biomarker for assessing clinical severity in COVID-19 patients., PMID:38865391
Impact of maternal immune activation and sex on placental and fetal brain cytokine and gene expression profiles in a preclinical model of neurodevelopmental disorders., PMID:38715090
Prophylactic treatment with PEGylated bovine IFNλ3 effectively bridges the gap in vaccine-induced immunity against FMD in cattle., PMID:38638908
Predictive Potential Of Il28b Gene In Hcv Patients, Resistant To Daclatasvir And Sofosbuvir In KPK Population., PMID:38406928
Cytokine profile and viral diversity in the early seronegative stage of community-acquired hepatitis C virus (HCV) infection., PMID:37973814
Cytokine polymorphisms and genotypic susceptibility of HCV infection in ribavirin response to peg interferon., PMID:37897166
Association between endothelin-1 and systemic lupus erythematosus: insights from a case-control study., PMID:37749230
Establishment of a porcine bronchial epithelial cell line and its application to study innate immunity in the respiratory epithelium., PMID:37465671
Influence of polymorphic variations of IFNL, HLA, and IL-6 genes in severe cases of COVID-19., PMID:37452704
Prediction of response to sofosbuvir-based therapy using serum interleukin-12 and single nucleotide polymorphism of the interleukin 28B gene as predictive factors in HCV positive genotype-4 patients., PMID:37443472
Polygenic Innate Immunity Score to Predict the Risk of Cytomegalovirus Infection in CMV D+/R- Transplant Recipients. A Prospective Multicenter Cohort Study., PMID:36016941
Intratumoral IL-28B Gene Delivery Elicits Antitumor Effects by Remodeling of the Tumor Microenvironment in H22-Bearing Mice., PMID:35935577
ASSESSING PREDICTORS OF DIRECTLY ACTING ANTIVIRALS' FAILURE AS A FURTHER STEP TOWARDS MORE EFFICIENT HCV ELIMINATION PROGRAMS: IL28B (IFNL4) GENE POLYMORPHISM HAS NO ROLE WHILE HIGHER ESTIMATED CREATININE CLEARANCE IS A FORGOTTEN FACTOR., PMID:35830025
Assessment of serum interleukin-28 as a biomarker to predict mortality in traumatic patients with sepsis., PMID:35816926
Favorable Genotypes of Type III Interferon Confer Risk of Dyslipidemia in the Population With Obesity., PMID:35784542
Immunotherapeutic potential of ethanolic olive leaves extract (EOLE) and IL-28B combination therapy in ENU induced animal model of leukemia., PMID:35640418
Interleukin-10 family members: Biology and role in the bone and joint diseases., PMID:35623292
Defining the key intrahepatic gene networks in HCV infection driven by sex., PMID:35613843
IFNL4 genotype influences the rate of HIV-1 seroconversion in men who have sex with men., PMID:35481423
Innate antiviral responses in porcine nasal mucosal explants inoculated with influenza A virus are comparable with responses in respiratory tissues after viral infection., PMID:35255458
Association between Psoriasis Disease and IFN-λ Gene Polymorphisms., PMID:35118914
Mechanistic insight into the synergism of IL-27 and IL-28B in regulation of benzo(a)pyrene-induced lung carcinogenesis associated ROS/NF-κB/NLRP3 crosstalk., PMID:34999049
The impact of single-nucleotide polymorphisms on liver stiffness and controlled attenuation parameter in patients treated with direct-acting antiviral drugs for hepatitis C infection., PMID:34987793
Synergism therapeutic and immunoregulatory effects of Albendazole + rAd-mIL-28B against Echinococcosis in experiment-infected mice with protoscoleces., PMID:34818327
Possible relationship between IL28B rs12979860 and TLR2 -196 to -174 del/ins polymorphisms and the liver fibrosis stage in hepatitis C patients., PMID:34817649
Single Nucleotide Polymorphisms of Interleukins and Toll-like Receptors and Neuroimaging Results in Newborns with Congenital HCMV Infection., PMID:34578364
Association of IL28 B and IL10 Polymorphism with HCV Infection and Direct Antiviral Treatment., PMID:34452889
[Investigation of the Relationship Between IL28B Polymorphisms and Plasma IL28B Levels in Patients with Chronic Hepatitis B or C]., PMID:34416803
Posttreatment Downregulation of Type III Interferons in Patients with Acute Brucellosis., PMID:34335092
Correlation between IL-28 polymorphism and spontaneous clearance in HCV patients: systematic review and meta-analysis., PMID:34216268
IL28B, TLR7 SNPs, and cytomegalovirus infection are risk factors for advanced liver disease in chronic hepatitis C patients., PMID:34047252
Association between interleukin 28B polymorphism and sustained virological response to sofosbuvir plus daclatasvir in chronic hepatitis C genotype 4 Egyptian patients., PMID:33768560
Functional genetic variants of the IFN-λ3 (IL28B) gene and transcription factor interactions on its promoter., PMID:33725487
The role of interleukin-10 family members in cardiovascular diseases., PMID:33662690
Interferon-γ inducible protein-10 and interleukin 28B gene polymorphism as predictive markers for genotype 4 hepatitis C virus treatment response., PMID:33612760
Inhibition of Type III Interferon Expression in Intestinal Epithelial Cells-A Strategy Used by Coxsackie B Virus to Evade the Host's Innate Immune Response at the Primary Site of Infection?, PMID:33466313
Pegylated interferon and ribavirin gone but not forgotten in the era of direct-acting antivirals., PMID:33438851
Protective cellular and mucosal immune responses following nasal administration of a whole gamma-irradiated influenza A (subtype H1N1) vaccine adjuvanted with interleukin-28B in a mouse model., PMID:33409549
Interleukin-28B dampens protease-induced lung inflammation via IL-25 and TSLP inhibition in epithelial cells., PMID:33262394
For research use only. Not for human or drug use.
