Catalog No.
YHJ14301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val265-His402
Predicted molecular weight
17.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q7Z5Y6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BMP8A, Bone morphogenetic protein 8A, BMP-8A
The effect of osteoclasts on epigenetic regulation by long non-coding RNAs in osteoblasts grown on titanium with nanotopography., PMID:39622096
Upregulated bone morphogenetic protein 8A (BMP8A) in triple negative breast cancer (TNBC) and its involvement in the bone metastasis., PMID:39100096
The prognostic significance and immune characteristics of bone morphogenetic proteins (BMPs) family: A pan-cancer multi-omics analysis., PMID:39031404
Coding and noncoding RNA profile of human heterotopic ossifications - Risk factors and biomarkers., PMID:37597797
Bmp8a deletion leads to obesity through regulation of lipid metabolism and adipocyte differentiation., PMID:37553521
FAM20A mutations and transcriptome analyses of dental pulp tissues of enamel renal syndrome., PMID:37159186
Circulating bone morphogenetic protein 8A is a novel biomarker to predict advanced liver fibrosis., PMID:37106416
Roles of miR-196a and miR-196b in Zebrafish Motor Function., PMID:36979489
Genome-wide identification, evolution and expression analysis of bone morphogenetic protein (BMP) gene family in chinese soft-shell turtle (Pelodiscus sinensis)., PMID:36816024
Recent progress in the biology and physiology of BMP-8a., PMID:36594156
Unveiling the transcriptomic landscape and the potential antagonist feedback mechanisms of TGF-β superfamily signaling module in bone and osteoporosis., PMID:36443839
Export of polybasic motif-containing secretory proteins BMP8A and SFRP1 from the endoplasmic reticulum is regulated by surfeit locus protein 4., PMID:36370847
Identification of N-Glycoproteins of Knee Cartilage from Adult Osteoarthritis and Kashin-Beck Disease Based on Quantitative Glycoproteomics, Compared with Normal Control Cartilage., PMID:36010590
Bmp8a is an essential positive regulator of antiviral immunity in zebrafish., PMID:33750893
Gene expression profiling of giant fibroadenomas of the breast., PMID:33677364
Down-regulation of the Sp1 transcription factor by an increase of microRNA-4497 in human placenta is associated with early recurrent miscarriage., PMID:33579314
Human bone morphogenetic protein 8A promotes expansion and prevents apoptosis of cumulus cells in vitro., PMID:33338549
Tympanosclerosis and atherosclerosis plaques: a comparative analytical study on some new microbiological and immunohistochemical aspects., PMID:33140144
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma., PMID:32128917
Exploring the role of Luman/CREB3 in regulating decidualization of mice endometrial stromal cells by comparative transcriptomics., PMID:32000663
Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway., PMID:31940275
Serous BMP8A has Clinical Significance in the Ultrasonic Diagnosis of Thyroid Cancer and Promotes Thyroid Cancer Cell Progression., PMID:31656161
High expression of bone morphogenetic protein (BMP) 6 and BMP7 are associated with higher immune cell infiltration and better survival in estrogen receptor‑positive breast cancer., PMID:31524275
Association study of copy number variation in BMP8A gene with the risk of ankylosing spondylitis in Iranian population., PMID:30485530
Characterization and spatiotemporal expression analysis of nine bone morphogenetic protein family genes during intermuscular bone development in blunt snout bream., PMID:29129809
BMP8A sustains spermatogenesis by activating both SMAD1/5/8 and SMAD2/3 in spermatogonia., PMID:28465413
Genetic Variants in the Bone Morphogenic Protein Gene Family Modify the Association between Residential Exposure to Traffic and Peripheral Arterial Disease., PMID:27082954
Postnatal expression of bone morphogenetic proteins and their receptors in the mouse testis., PMID:26988160
Esophageal Cancer Epigenomics and Integrome Analysis of Genome-Wide Methylation and Expression in High Risk Northeast Indian Population., PMID:26496483
Inhibitory role of REV-ERBα in the expression of bone morphogenetic protein gene family in rat uterus endometrium stromal cells., PMID:25588874
Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a., PMID:25451979
BMP system expression in GCs from polycystic ovary syndrome women and the in vitro effects of BMP4, BMP6, and BMP7 on GC steroidogenesis., PMID:23243014
Genes that characterize T3-predominant Graves' thyroid tissues., PMID:23109646
Genome-wide DNA methylation studies suggest distinct DNA methylation patterns in pediatric embryonal and alveolar rhabdomyosarcomas., PMID:22419069
Tissue remodeling in the acute otitis media mouse model., PMID:21889218
Effects of cartilage-derived morphogenetic protein-3 on the expression of chondrogenic and osteoblastic markers in the pluripotent mesenchymal C3H10T1/2 cell line., PMID:20102312
Identification of differentially expressed genes between osteoblasts and osteocytes., PMID:19539797
Global comparative transcriptome analysis of cartilage formation in vivo., PMID:19272164
Genetic profile of Egyptian hepatocellular-carcinoma associated with hepatitis C virus Genotype 4 by 15 K cDNA microarray: preliminary study., PMID:18959789
Comparative integromics on BMP/GDF family., PMID:16596286
Developmental expression and function of Bmp4 in spermatogenesis and in maintaining epididymal integrity., PMID:15531371
Gene structure and evolution of testicular haploid germ cell-specific genes, Oxct2a and Oxct2b., PMID:15028287
Differentiation of murine preosteoblastic KS483 cells depends on autocrine bone morphogenetic protein signaling during all phases of osteoblast formation., PMID:12531559
Mutation in Bmp7 exacerbates the phenotype of Bmp8a mutants in spermatogenesis and epididymis., PMID:11784057
Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouse., PMID:11401407
Detection of multiple bone morphogenetic protein messenger ribonucleic acids and their signal transducer, Smad1, during mouse decidualization., PMID:11090449
Lineage-restricted expression of bone morphogenetic protein genes in human hematopoietic cell lines., PMID:10660478
Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis., PMID:9463357
Evidence that mouse Bmp8a (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development., PMID:8843393
For research use only. Not for human or drug use.
