Catalog No.
YHJ05001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser24-Thr164
Predicted molecular weight
18.14 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6EBC2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IL-31, Interleukin-31, IL31
Antipruritic Effect of 2,3-Dehydrosilybin in Glial Cells and Chloroquine-Treated Mice., PMID:40443235
Use of Nemolizumab in the Treatment of Prurigo Nodularis and Atopic Dermatitis., PMID:40403168
Nemolizumab Improves Pruritus in Patients With Intrinsic Atopic Dermatitis Lacking Atopic Predisposition: A Single-Centre Pilot Retrospective Cohort Study., PMID:40372094
Tartaric Acid Exacerbates DSS-Induced Colitis by Promoting Eosinophilic Inflammation via IL-13 and IL-5Rα Upregulation., PMID:40333150
Serum Concentrations of IL-18, IL-21, IL-22, IL-23, IL-27, and IL-31 in Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis and Their Correlation With Disease Severity., PMID:40322299
The Role of Eosinophils, Eosinophil-Related Cytokines and AI in Predicting Immunotherapy Efficacy in NSCLC., PMID:40305195
New and Emerging Biologics and Jak Inhibitors for the Treatment of Prurigo Nodularis: A Narrative Review., PMID:40282922
Evaluation of pruritus biomarkers expression in chronic spontaneous urticaria., PMID:40261414
Osthole ameliorates chronic pruritus in 2,4-dichloronitrobenzene-induced atopic dermatitis by inhibiting IL-31 production., PMID:40256714
Topical Application of Fluoxetine Improves DNCB-Induced Atopic Dermatitis in Mice., PMID:40243303
Effectiveness and Safety of Nemolizumab in Patients with Prurigo Nodularis: a Systematic Review and Meta-Analysis of Randomized Controlled Trials., PMID:40205064
Phenotype-endotype relationship in elderly atopic dermatitis and effects of dupilumab therapy: prospective study., PMID:40095170
Effect of the Combination of Hemodialysis and., PMID:40056446
Clinical Investigation of IL-31, TOS and GSH in the Sera of Gastric Cancer Females Patients In Iraq., PMID:40022705
Assessing the Causal Relationship Between Plasma Proteins and Pulmonary Fibrosis: A Systematic Analysis Based on Mendelian Randomization., PMID:40001968
Elevated Type 2 Inflammatory Factors, Th2/Th1 Balanced Status, and Exosomes as a Marker of Severity in Chronic Actinic Dermatitis., PMID:39949921
WISIT vaccines based on IL-31-derived peptides as a novel therapeutic approach for chronic pruritic dermatoses., PMID:39932924
Pre- and Postnatal Development Study of Nemolizumab, a Humanized Anti-Interleukin-31 Receptor A Monoclonal Antibody, in Cynomolgus Monkey., PMID:39868832
IL-4, TSLP and IL-31 Cytokine Profiles as Related to Psychometric Measures in Patients with Mastocytosis., PMID:39859245
Exploring the Involvement of New Members of the Interleukin Family in Cardiovascular Disease., PMID:39844544
Reconstructed Epidermis Produced with Atopic Dog Keratinocytes Only Exhibit Skin Barrier Defects after the Addition of Proinflammatory and Allergic Cytokines., PMID:39811760
Type 2 cytokine-JAK1 signaling is involved in the development of dry skin-induced mechanical alloknesis., PMID:39616021
Predictive cytokines of omalizumab in the treatment of chronic spontaneous urticaria., PMID:39602877
Interleukin 31 mediates pruritus in horses., PMID:39406262
Comparative effectiveness of upadacitinib versus dupilumab for moderate-to-severe atopic dermatitis: A retrospective cohort study., PMID:39405928
The diagnostic value and validation of IL-22 combimed with sCD40L in tuberculosis pleural effusion., PMID:39385103
Biomarkers of type 2 and non-type 2 inflammation in asthma exacerbations., PMID:39381551
Emerging Biologic Therapies for the Treatment of Atopic Dermatitis., PMID:39365406
Oral Administration of Lactococcus lactis Expressing Mite and Cockroach Major Allergens Alleviates Progression of Atopic March in a Mouse Model., PMID:39363770
Interleukin-31: The Inflammatory Cytokine Connecting Pruritus and Cancer., PMID:39344323
Cytokine profile of the stratum corneum in atopic dermatitis lesions differs between the face and the trunk., PMID:39332980
Interleukin 31 in vitiligo patients with and without pruritus., PMID:39324348
OpzeluraTM (Ruxolitinib) Cream 1.5., PMID:39285571
Cannabinol modulates the endocannabinoid system and shows TRPV1-mediated anti-inflammatory properties in human keratinocytes., PMID:39275884
Pyrazolines inhibiting the activity of the early growth response-1 DNA-binding domain., PMID:39265893
Cord Blood Serum Levels of IL-31 and CCL17, Cutaneous Markers, and Development of Atopic Dermatitis., PMID:39259556
Comparison of serum cytokines and chemokines levels and clinical significance in patients with pemphigus vulgaris-A retrospective study., PMID:39246287
Trichohyalin gene expression is negatively correlated with the severity of dermatitis in a canine atopic dermatitis model., PMID:39234173
Anti-atopic dermatitis effect of fraxinellone via inhibiting IL-31 in vivo and in vitro., PMID:39170490
Long-term use of lokivetmab in dogs with atopic dermatitis., PMID:39143659
Diospyros lotus leaf extract and its main component myricitrin inhibit itch‑related IL‑6 and IL‑31 by suppressing microglial inflammation and microglial‑mediated astrocyte activation., PMID:39129303
Interleukin Profiling in Atopic Dermatitis and Chronic Nodular Prurigo., PMID:39126011
Lasmiditan ameliorates serotonergic itch in mice: Possible involvement of 5-HT1F receptors., PMID:39115558
Cytokines and chemokines skin gene expression in correlation with immune cells in blood and severity in equine insect bite hypersensitivity., PMID:39076967
Characterization of cells and mediators associated with pruritus in primary cutaneous T-cell lymphomas., PMID:39068637
Nemolizumab with concomitant topical therapy in adolescents and adults with moderate-to-severe atopic dermatitis (ARCADIA 1 and ARCADIA 2): results from two replicate, double-blind, randomised controlled phase 3 trials., PMID:39067461
Celastrol alleviates atopic dermatitis by regulating Ezrin-mediated mitochondrial fission and fusion., PMID:39039796
Clinical characteristics, immunological alteration and distinction of MOG-IgG-associated disorders and GFAP-IgG-associated disorders., PMID:39002186
Inflammatory profile of patients with different weight diagnoses and similar periodontal condition: A systematic review., PMID:38988953
Altered expression of cytokines, chemokines, growth factors, and soluble receptors in patients with colorectal cancer, and correlation with treatment outcome., PMID:38954024
For research use only. Not for human or drug use.
