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Research Grade Navicixizumab (DHJ65303)

Host species:Humanized
Isotype:IgG2-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHJ65303

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG2-kappa

Clonality

Monoclonal

Target

Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4, Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NR61 & P15692

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

Bispecific, OMP-305B83, CAS: 1638338-43-8

Clone ID

Navicixizumab

Data Image
  • SDS-PAGE
    SDS PAGE for Navicixizumab
  • Bioactivity
    Detects DLL4 in indirect ELISAs.
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

A first-in-human phase 1a study of the bispecific anti-DLL4/anti-VEGF antibody navicixizumab (OMP-305B83) in patients with previously treated solid tumors, PMID: 30229512

NOTCH signalling in ovarian cancer angiogenesis, PMID: 33490217

Datasheet

Document Download

Research Grade Navicixizumab.pdf

 

$ 484
Product specifications
100 μg 484 1 mg 1932

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Navicixizumab [DHJ65303]
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