Catalog No.
YHE85401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu302-Leu352
Predicted molecular weight
32.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P51681
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C-C CKR-5, CC-CKR-5, CMKBR5, HIV-1 fusion coreceptor, CHEMR13, CCR5, C-C chemokine receptor type 5, CD195, CCR-5
A 16-color full spectrum flow cytometric analysis for comprehensive evaluation of T-cell reconstitution in SIV-infected rhesus macaques., PMID:36496008
Association of HLA genotypes, AB0 blood type and chemokine receptor 5 mutant CD195 with the clinical course of COVID-19., PMID:34530915
Single-cell mass cytometry of microglia in major depressive disorder reveals a non-inflammatory phenotype with increased homeostatic marker expression., PMID:32917850
Retinopathy severity correlates with RANTES concentrations and CCR 5-positive microvesicles in diabetes., PMID:31891363
Chemokine CCR5 and cocaine interactions in the brain: Cocaine enhances mesolimbic CCR5 mRNA levels and produces place preference and locomotor activation that are reduced by a CCR5 antagonist., PMID:31557508
Differential expression of genes and receptors in monocytes from patients with cystic fibrosis., PMID:30177416
Cigarette smoke condensate may disturb immune function with apoptotic cell death by impairing function of organelles in alveolar macrophages., PMID:30031032
Introduction of Human Flt3-L and GM-CSF into Humanized Mice Enhances the Reconstitution and Maturation of Myeloid Dendritic Cells and the Development of Foxp3+CD4+ T Cells., PMID:29892279
T-cell profile and systemic cytokine levels in overweight-obese patients with moderate to very-severe COPD., PMID:28963085
Immunomodulatory effects of heat-killed Mycobacterium obuense on human blood dendritic cells., PMID:28853313
Expansion of CD11b+Ly6Ghigh and CD11b+CD49d+ myeloid cells with suppressive potential in mice with chronic inflammation and light-at-night-induced circadian disruption., PMID:28455608
Immunomodulation of inflammatory leukocyte markers during intravenous immunoglobulin treatment associated with clinical efficacy in chronic inflammatory demyelinating polyradiculoneuropathy., PMID:27781132
Effects of conventional CPB and mini-CPB on neutrophils CD162, CD166 and CD195 expression., PMID:27625334
The tyrosine kinase inhibitor tyrphostin AG126 reduces activation of inflammatory cells and increases Foxp3+ regulatory T cells during pathogenesis of rheumatoid arthritis., PMID:27608299
Development and characterization of a human microglia cell model of HIV-1 infection., PMID:27538994
A higher aspect ratio enhanced bioaccumulation and altered immune responses due to intravenously-injected aluminum oxide nanoparticles., PMID:27042761
Evaluation of the inflammatory response in macrophages stimulated with exosomes secreted by Mycobacterium avium-infected macrophages., PMID:25861639
CCR5 blockage by maraviroc induces cytotoxic and apoptotic effects in colorectal cancer cells., PMID:25840792
Acute response of peripheral CCr5 chemoreceptor and NK cells in individuals submitted to a single session of low-intensity strength exercise with blood flow restriction., PMID:25643617
Characterization of γδT cells in naïve and HIV-infected chimpanzees and their responses to T-cell activators in vitro., PMID:24660852
Impact of parturition on chemokine homing factor expression in the vaginal distention model of stress urinary incontinence., PMID:23022009
Evaluation of cytotoxic T-cell activation, chemokine receptors, and adhesion molecules in blood and serum in patients with oral lichen planus., PMID:22404248
Several commercially available anti-CCR5 monoclonal antibodies lack specificity and should be used with caution., PMID:22316480
Abnormal B-cell activation associated with TALL-1 over-expression and SOCS-1 suppression during chronic hepatitis C virus infection., PMID:19740379
Assessment of lymphocyte proliferation: CFSE kills dividing cells and modulates expression of activation markers., PMID:19233349
Acute-phase CD4+ T-cell proliferation and CD152 upregulation predict set-point virus replication in vaccinated simian-human immunodeficiency virus strain 89.6p-infected macaques., PMID:19223489
HMG-CoA reductase inhibitors deplete circulating classical and non-classical monocytes following human heart transplantation., PMID:18503891
Decidual natural killer cell tuning by autologous dendritic cells., PMID:18405314
Differential regulation of SOCS-1 signalling in B and T lymphocytes by hepatitis C virus core protein., PMID:18397267
Activated T cell subsets in human type 1 diabetes: evidence for expansion of the DR+ CD30+ subpopulation in new-onset disease., PMID:17302896
Characterization of the expanded T-cell populations in patients with Wegener's granulomatosis., PMID:16918819
Mycobacterium tuberculosis-induced CXCR4 and chemokine expression leads to preferential X4 HIV-1 replication in human macrophages., PMID:15128813
Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI., PMID:12801524
Relation of CD30 molecules on T-cell subsets to the severity of autoimmune thyroid disease., PMID:12729474
For research use only. Not for human or drug use.
