Catalog No.
RHN88502
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
FCM: 1:200-1:400, IF: 1:200-1:1000, WB: 1:500-1:2000
Target
DAP6, EAP1, ETS1-associated protein 1, Death domain-associated protein 6, DAXX, BING2, hDaxx, Daxx, Fas death domain-associated protein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UER7
Applications
FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4A56
Microglial Pdcd4 deficiency mitigates neuroinflammation-associated depression via facilitating Daxx mediated PPARγ/IL-10 signaling., PMID:38822367
Cross-reactivity of hantavirus antibodies after immunization with PUUV antigens., PMID:38779849
Gap junction intercellular communication mediates cadmium-induced apoptosis in hepatocytes via the Fas/FasL pathway., PMID:35920667
Identification of novel autoantibodies based on the protein chip encoded by cancer-driving genes in detection of esophageal squamous cell carcinoma., PMID:33457096
How to Tackle Challenging ChIP-Seq, with Long-Range Cross-Linking, Using ATRX as an Example., PMID:30073524
Phytochemical allylguaiacol exerts a neuroprotective effect on hippocampal cells and ameliorates scopolamine-induced memory impairment in mice., PMID:29126931
Nuclear domain 10 components upregulated via interferon during human cytomegalovirus infection potently regulate viral infection., PMID:28745271
High-resolution telomere fluorescence in situ hybridization reveals intriguing anomalies in germ cell tumors., PMID:27085557
DAXX modulates human papillomavirus early gene expression and genome replication in U2OS cells., PMID:26148509
Heat shock protein 27 overexpression in CHO cells modulates apoptosis pathways and delays activation of caspases to improve recombinant monoclonal antibody titre in fed-batch bioreactors., PMID:25740626
Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection., PMID:25275136
Subcellular localization of DAXX influence ox-LDL induced apoptosis in macrophages., PMID:25120166
Sp100 isoform-specific regulation of human adenovirus 5 gene expression., PMID:24623443
Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency., PMID:24586165
Distribution and location of Daxx in cervical epithelial cells with high risk human papillomavirus positive., PMID:24398161
Human cytomegalovirus pUL97 regulates the viral major immediate early promoter by phosphorylation-mediated disruption of histone deacetylase 1 binding., PMID:23616659
The SUMO ligase PIAS1 regulates UV-induced apoptosis by recruiting Daxx to SUMOylated foci., PMID:22976298
Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas., PMID:22928601
Role of CD137 signaling in dengue virus-mediated apoptosis., PMID:21669186
Mechanisms of the apoptosis induced by CD176 antibody in human leukemic cells., PMID:21455576
Cytoplasmic relocation of Daxx induced by Ro52 and FLASH., PMID:20697732
Modulation of the Zac1's transactivation and coactivation functions via PML and Daxx within distinct subcellular localizations., PMID:20097304
Emerging roles of the EBF family of transcription factors in tumor suppression., PMID:19996307
Nuclear localization of dengue virus capsid protein is required for DAXX interaction and apoptosis., PMID:19944121
Transforming growth factor β inducible apoptotic cascade in epithelial cells during rat molar tooth eruptions., PMID:19779767
Tollip is a mediator of protein sumoylation., PMID:19198660
Expression pattern and subcellular localization of human papillomavirus minor capsid protein L2., PMID:19095951
Type I IFNs enhance susceptibility to Chlamydia muridarum lung infection by enhancing apoptosis of local macrophages., PMID:18641348
Critical roles for JNK, c-Jun, and Fas/FasL-Signaling in vitamin E analog-induced apoptosis in human prostate cancer cells., PMID:18196534
Association of TRAF2 with the short form of cellular FLICE-like inhibitory protein prevents TNFR1-mediated apoptosis., PMID:18190721
4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas., PMID:18069800
A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx., PMID:17938171
Sensitization to Fas-mediated apoptosis by dengue virus capsid protein., PMID:17707345
Human cytomegalovirus gene expression is silenced by Daxx-mediated intrinsic immune defense in model latent infections established in vitro., PMID:17596307
Anti-apoptotic effects of probucol are associated with downregulation of Daxx expression in THP-1 macrophage., PMID:17370120
Oncolytic vesicular stomatitis virus induces apoptosis via signaling through PKR, Fas, and Daxx., PMID:17192316
Fas (CD95) ligation inhibits activation of NF-kappa B by targeting p65-Rel A in a caspase-dependent manner., PMID:16765090
[Expression of apoptosis-related proteins in the human bone marrow hematopoietic cells treated by Panax Notoginosides]., PMID:16638211
The PML-nuclear body associated protein Daxx regulates the cellular response to CD40., PMID:16311507
Hydrogen peroxide predisposes neonatal rat ventricular myocytes to Fas-mediated apoptosis., PMID:16157298
Differential effects of a novel IFN-zeta/limitin and IFN-alpha on signals for Daxx induction and Crk phosphorylation that couple with growth control of megakaryocytes., PMID:15781341
Daxx overexpression in T-lymphoblastic Jurkat cells enhances caspase-dependent death receptor- and drug-induced apoptosis in distinct ways., PMID:15683733
Negative modulation of androgen receptor transcriptional activity by Daxx., PMID:15572661
Fas gene mutations in mycosis fungoides: analysis of laser capture-microdissected specimens from cutaneous lesions., PMID:15539917
Expression of a dominant negative form of Daxx in vivo rescues motoneurons from Fas (CD95)-induced cell death., PMID:15459896
Anti-apoptotic mechanism and reduced expression of phospholipase D in spontaneous and Fas-stimulated apoptosis of human neutrophils., PMID:15368292
In the erythroleukemic cell line HEL Prostate-apoptosis-response-gene-4 (par-4) fails to down-regulate Bcl-2 and to promote apoptosis., PMID:15359646
Cloning and functional characterization of a rat Daxx that functions as a corepressor for the androgen receptor., PMID:15350595
In bcr-abl-positive myeloid cells resistant to conventional chemotherapeutic agents, expression of Par-4 increases sensitivity to imatinib (STI571) and histone deacetylase-inhibitors., PMID:15183120
Physical and functional interactions between Daxx and TSG101., PMID:15033475