Catalog No.
                        DHJ53501
                        
                                            
                                            
                                            Expression system
                        
                        Mammalian Cells                        
                                                
                                            
                                            
                                            
                                            
                                            Species reactivity
                        
                        Human                        
                                                
                                            Host species
                        
                        Human                        
                                                
                                            Isotype
                        
                        IgG1-lambda                        
                                                
                                            Clonality
                        
                        Monoclonal                        
                                                
                                            
                                            
                                            
                                            Target
                        
                        Interleukin-22, Cytokine Zcyto18, IL-22, ZCYTO18, IL22, ILTIF, IL-TIF, IL-10-related T-cell-derived-inducible factor                        
                                                
                                            
                                            Concentration
                        
                        1 mg/ml                        
                                                
                                            Endotoxin level
                        
                        Please contact with the lab for this information.                        
                                                
                                            Purity
                        
                        >95% as determined by SDS-PAGE.                        
                                                
                                            Purification
                        
                        Protein A/G purified from cell culture supernatant.                        
                                                
                                            Accession
                        
                        Q9GZX6                        
                                                
                                            
                                            Applications
                        
                        Research Grade Biosimilar                        
                                                
                                            Form
                        
                        Liquid                        
                                                
                                            Storage buffer
                        
                        0.01M PBS, pH 7.4.                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Stability and Storage
                        
                        Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.                        
                                                
                                            
                                            
                                                Alternative Names
                            ILV-094, CAS: 1007106-86-6
                            
                                                        Clone ID
                            Fezakinumab
                            
                                                    
                                            
                                            
                                        
                 
                
                
                                            A Double Edged Sword Role of Interleukin-22 in Wound Healing and Tissue Regeneration, PMID: 33042126
                                            A mathematical model to identify optimal combinations of drug targets for dupilumab poor responders in atopic dermatitis, PMID: 33894014
                                            Baseline IL-22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab, PMID: 30121291
                                            Biological therapies for atopic dermatitis: An update, PMID: 30679974
                                            Efficacy and safety of fezakinumab (an IL-22 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by conventional treatments: A randomized, double-blind, phase 2a trial, PMID: 29353025
                                            Efficacy of biologics in atopic dermatitis, PMID: 32003247
                                            Mapping atopic dermatitis and anti-IL-22 response signatures to type 2-low severe neutrophilic asthma, PMID: 33891981
                                            New therapies for atopic dermatitis: Additional treatment classes, PMID: 29248520
                                            Novel systemic drugs in treatment of atopic dermatitis: results from phase II and phase III studies published in 2017/2018, PMID: 30095475
                                            Novel Targeted Biological Agents for the Treatment of Atopic Dermatitis, PMID: 34213742
                                            Novel Therapeutic Approaches and Targets for the Treatment of Atopic Dermatitis, PMID: 32525769
                                            Review and analysis of biologic therapies currently in phase II and phase III clinical trials for atopic dermatitis, PMID: 32507066
                                            Systemic Therapy of Atopic Dermatitis: Welcome to the Revolution, PMID: 29659645
                                            The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis, PMID: 30319661
                                            What's New in Atopic Dermatitis, PMID: 30850043
                                            IL-22 in Atopic Dermatitis., PMID:39195286
                                            Interplay of cytokines in the pathophysiology of atopic dermatitis: insights from Murin models and human., PMID:38590314
                                            Machine learning-based prediction models for atopic dermatitis diagnosis and evaluation., PMID:40528978
                                            Safety and Danger Considerations of Novel Treatments for Atopic Dermatitis in Context of Primary Cutaneous Lymphomas., PMID:34948183
                                            [Novel therapies in the treatment of atopic dermatitis]., PMID:34919093
                                            Transcriptomic drug-response gene signatures are informative for the stratification of patients for clinical trials., PMID:34582880
                                            Novel Targeted Biological Agents for the Treatment of Atopic Dermatitis., PMID:34213742
                                            A mathematical model to identify optimal combinations of drug targets for dupilumab poor responders in atopic dermatitis., PMID:33894014
                                            Mapping atopic dermatitis and anti-IL-22 response signatures to type 2-low severe neutrophilic asthma., PMID:33891981
                                            Biological Therapies for Atopic Dermatitis: A Systematic Review., PMID:33735876
                                            A Double Edged Sword Role of Interleukin-22 in Wound Healing and Tissue Regeneration., PMID:33042126
                                            Novel Therapeutic Approaches and Targets for the Treatment of Atopic Dermatitis., PMID:32525769
                                            Review and analysis of biologic therapies currently in phase II and phase III clinical trials for atopic dermatitis., PMID:32507066
                                            Efficacy of biologics in atopic dermatitis., PMID:32003247
                                            What's New in Atopic Dermatitis., PMID:30850043
                                            Biological therapies for atopic dermatitis: An update., PMID:30679974
                                            The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis., PMID:30319661
                                            Baseline IL-22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab., PMID:30121291
                                            Novel systemic drugs in treatment of atopic dermatitis: results from phase II and phase III studies published in 2017/2018., PMID:30095475
                                            Efficacy and safety of fezakinumab (an IL-22 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by conventional treatments: A randomized, double-blind, phase 2a trial., PMID:29353025
                                            New therapies for atopic dermatitis: Additional treatment classes., PMID:29248520
                                            Systemic Therapy of Atopic Dermatitis: Welcome to the Revolution., PMID:29659645