Catalog No.
YHD36601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu38-Gln247
Predicted molecular weight
24.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P19971
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ECGF1, Gliostatin, Platelet-derived endothelial cell growth factor, TYMP, TdRPase, Thymidine phosphorylase, TP, PD-ECGF
Causal association between plasma proteins and lung adenocarcinoma: a two-sample mendelian randomization study., PMID:40468286
Verification of biological markers of subacute cutaneous lupus erythematosus via TMT labelling proteomics combined with transcriptome data., PMID:40323689
Thymidine phosphorylase in nucleotide metabolism: physiological functions and its implications in tumorigenesis and anti-cancer therapy., PMID:40303404
Activation and targetability of TYMP-IL-6-TF signaling in the skin microenvironment in uremic calciphylaxis., PMID:40267216
Multiscale Simulations and Profiling of Human Thymidine Phosphorylase Mutations: Insights into Structural, Dynamics, and Functional Impacts in Mitochondrial Neurogastrointestinal Encephalopathy., PMID:40111159
Potential drug targets for ovarian cancer identified through Mendelian randomization and colocalization analysis., PMID:39972314
Proteomics unveil candidate biomarkers and pathogenesis of subacute thyroiditis., PMID:39807704
Transcription factor MAZ activates the transcription of hypomethylated TYMP in ccRCC., PMID:39797954
Causal associations between circulating protein ratios and drug resistance in papillary thyroid cancer: a Mendelian randomization study., PMID:39754686
Thymidine Phosphorylase Promotes Abdominal Aortic Aneurysm via VSMC Modulation and Matrix Remodeling in Mice and Humans., PMID:39742002
Thymidine phosphorylase participates in platelet activation and promotes inflammation in rheumatoid arthritis., PMID:39732205
TBK1 Reprograms Metabolism in Breast Cancer: An Integrated Omics Approach., PMID:39670797
ADAMDEC1 promotes cervical squamous cell carcinoma by enhancing the JAK/STAT signaling pathway through modulation of TYMP., PMID:39625490
Proteomic profiling of gliomas unveils immune and metabolism-driven subtypes with implications for anti-nucleotide metabolism therapy., PMID:39562821
Integrated proteomics and scRNA-seq analyses of ovarian cancer reveal molecular subtype-associated cell landscapes and immunotherapy targets., PMID:39548315
Thymidine Phosphorylase Imaging Probe for Differential Diagnosis of Metabolic dysfunction-associated Steatohepatitis., PMID:39538096
Discovery of PANoptosis-related signatures correlates with immune cell infiltration in psoriasis., PMID:39480805
Tumor-associated macrophages confer resistance to chemotherapy (Trifluridine/Tipiracil) in digestive cancers by overexpressing thymidine phosphorylase., PMID:39454852
Thymidine phosphorylase mediates SARS-CoV-2 spike protein enhanced thrombosis in K18-hACE2TG mice., PMID:39442286
Investigating potential novel therapeutic targets and biomarkers for ankylosing spondylitis using plasma protein screening., PMID:39185422
Identification and role of differentially expressed genes/proteins between pulmonary tuberculosis patients and controls across lung tissues and blood samples., PMID:39023413
Lysosomal dysfunction and overload of nucleosides in thymidine phosphorylase deficiency of MNGIE., PMID:38741129
Insights from the SNP analysis of TYMP gene linking MNGIE., PMID:38712004
Innovate therapeutic targets for autoimmune diseases: insights from proteome-wide mendelian randomization and Bayesian colocalization., PMID:38515381
Mendelian randomization identifies circulating proteins as biomarkers for age at menarche and age at natural menopause., PMID:38184718
Identifying TYMP as an Immune Prognostic Marker in Clear Cell Renal Cell Carcinoma., PMID:38043946
Proteome profiling identifies circulating biomarkers associated with hepatic steatosis in subjects with Prader-Willi syndrome., PMID:38034016
Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis., PMID:37903821
Evaluation of potential targets to enhance the sensitivity of cholangiocarcinoma cells to anticancer drugs., PMID:37832404
Immuno-oncologic signature of malignant transformation in oral squamous cell carcinoma., PMID:37739913
Distinctive metabolic remodeling in TYMP deficiency beyond mitochondrial dysfunction., PMID:37603049
Identification of the key genes of tuberculosis and construction of a diagnostic model via weighted gene co-expression network analysis., PMID:37499902
Regulatory pathway underpinning the development of encephalitis after simian immunodeficiency virus infection in rhesus macaques (Macaca mulatta)., PMID:37277966
Thymidine phosphorylase facilitates retinoic acid inducible gene-I induced endothelial dysfunction., PMID:37100811
Thymidine Phosphorylase Deficiency or Inhibition Preserves Cardiac Function in Mice With Acute Myocardial Infarction., PMID:36974758
Potential drug targets for multiple sclerosis identified through Mendelian randomization analysis., PMID:36864689
IL-17A and TNF-α inhibitors induce multiple molecular changes in psoriasis., PMID:36483564
WARS1, TYMP and GBP1 display a distinctive microcirculation pattern by immunohistochemistry during antibody-mediated rejection in kidney transplantation., PMID:36352007
What Do the Transcriptome and Proteome of Menstrual Blood-Derived Mesenchymal Stem Cells Tell Us about Endometriosis?, PMID:36232817
Rare pathogenic mutation in the thymidine phosphorylase gene (TYMP) causing mitochondrial neurogastrointestinal encephalomyelopathy., PMID:36072350
Multiplex protein profiling of bronchial aspirates reveals disease-, mortality- and respiratory sequelae-associated signatures in critically ill patients with ARDS secondary to SARS-CoV-2 infection., PMID:35967328
A novel thymidine phosphorylase mutation in a family with Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE): Molecular docking, dynamic simulation and computational investigations., PMID:35841120
Impact of thymidine phosphorylase and CD163 expression on prognosis in stage II colorectal cancer., PMID:35567733
Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes., PMID:35341481
The Proteome of Antibody-Mediated Rejection: From Glomerulitis to Transplant Glomerulopathy., PMID:35327371
The proteomic characterization of the peritumor microenvironment in human hepatocellular carcinoma., PMID:35314790
Platelet-Derived Drug Targets and Biomarkers of Ischemic Stroke-The First Dynamic Human LC-MS Proteomic Study., PMID:35268287
Effect of Thymidine Phosphorylase Gene Demethylation on Sensitivity to 5-Fluorouracil in Colorectal Cancer Cells., PMID:35093881
Polycyclic nitrogen heterocycles as potential thymidine phosphorylase inhibitors: synthesis, biological evaluation, and molecular docking study., PMID:34933639
Tissue Proteomic Analysis Identifies Mechanisms and Stages of Immunopathology in Fatal COVID-19., PMID:34710339
For research use only. Not for human or drug use.
