Research Grade Fletikumab (DHJ69101)

Catalog No.

DHJ69101

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG4-kappa

Clonality

Monoclonal

Target

IL20, Cytokine Zcyto10, ZCYTO10, IL-20, Interleukin-20

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NYY1

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

15D2, NN-8226, NNC-0109-0012, CAS: 1357158-22-5

Clone ID

Fletikumab

Clinical pharmacokinetics of the anti-interleukin-20 monoclonal antibody NNC0109-0012 in healthy volunteers and patients with psoriasis or rheumatoid arthritis, PMID: 25749867

Efficacy and Safety of Anti-Interleukin-20 Monoclonal Antibody in Patients With Rheumatoid Arthritis: A Randomized Phase IIa Trial, PMID: 25707477

First-In-Human, Phase 1, Randomized, Dose-Escalation Trial with Recombinant Anti-IL-20 Monoclonal Antibody in Patients with Psoriasis, PMID: 26252485

The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis, PMID: 30319661

Document Download

Research Grade Fletikumab.pdf