Catalog No.
YHD10401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg25-Ser234
Predicted molecular weight
26.97 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P15328
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Folate receptor alpha, FOLR, FOLR1, Adult folate-binding protein, Folate receptor 1, FR-alpha, KB cells FBP, FBP, Ovarian tumor-associated antigen MOv18, Folate receptor, adult
Folate Receptor Alpha in Advanced Epithelial Ovarian Cancer: Diagnostic Role and Therapeutic Implications of a Clinically Validated Biomarker., PMID:40508029
Personalized Treatment in Ovarian Cancer: A Review of Disease Monitoring, Biomarker Expression, and Targeted Treatments for Advanced, Recurrent Ovarian Cancers., PMID:40507303
Folate transfer in placental choriocarcinoma cells treated with valproic acid: Insights gained through comparisons with the amide derivative sec-butylpropylacetamide and its individual stereoisomers., PMID:40464080
FRα expression in advanced endometrial carcinoma: Clinicopathological, molecular, and prognosis correlates., PMID:40344965
Identification of potential cell surface targets in patient-derived cultures toward photoimmunotherapy of high-grade serous ovarian cancer., PMID:40205302
Patient-reported outcomes from the MIRASOL trial evaluating mirvetuximab soravtansine versus chemotherapy in patients with folate receptor α-positive, platinum-resistant ovarian cancer: a randomised, open-label, phase 3 trial., PMID:40179908
Sex-specific modulation of FOLR1 and its cycle enzyme genes in Alzheimer's disease brain regions., PMID:40153031
FOLR1 as a therapeutic target in platinum-resistant ovarian carcinoma: unique expression patterns across ovarian carcinoma histotypes and molecular subtypes of low-grade serous carcinoma., PMID:40150910
A review of mirvetuximab soravtansine-gynx in folate receptor alpha-expressing platinum-resistant ovarian cancer., PMID:40126684
Patient outcomes in advanced ovarian cancer treated with an anti-FOLR1 antibody-drug conjugate., PMID:40121972
Folate receptor 1 is a stemness trait-associated diagnostic and prognostic marker for hepatocellular carcinoma., PMID:40038575
IMGN853 Induces Autophagic Cell Death in Combination Therapy for Ovarian Cancer., PMID:40029935
Mirvetuximab Soravtansine Induces Potent Cytotoxicity and Bystander Effect in Cisplatin-Resistant Germ Cell Tumor Cells., PMID:39996761
NSD2 mediated H3K36me2 promotes pulmonary arterial hypertension by recruiting FOLR1 and metabolism reprogramming., PMID:39798773
Unraveling the elongating bovine conceptus microenvironment: identification of gene transcripts and proteins along the conceptus-maternal interface in cattle†., PMID:39775669
Computational insights into maternal environmental pollutants and folate pathway regulation., PMID:39732410
A pilot study of transcriptomic preimplantation genetic testing (PGT-T): towards a new step in embryo selection?, PMID:39719045
[DNA Methylation Profiling in Aneurysm and Comorbid Atherosclerosis of the Ascending Aorta]., PMID:39707852
Expression-Dependent Tumor Pretargeting via Engineered Avidity., PMID:39704255
Development and evaluation of a single domain antibody targeting folate receptor alpha for radioligand therapy., PMID:39696571
Folate prevents the autism-related phenotype caused by developmental pyrethroid exposure in prairie voles., PMID:39651146
Analysis of real world FRα testing in ovarian, fallopian tube, and primary peritoneal cancers., PMID:39631181
The efficacy and safety of mirvetuximab soravtansine in FRα-positive, third-line and later, recurrent platinum-sensitive ovarian cancer: the single-arm phase II PICCOLO trial., PMID:39617145
Deciphering Folate Receptor alphaGene Expression and mRNA Signatures in Ovarian Cancer: Implications for Precision Therapies., PMID:39596024
Folate Receptor Alpha-A Secret Weapon in Ovarian Cancer Treatment?, PMID:39595996
Identification and Characterization of Fully Human FOLR1-Targeting CAR T Cells for the Treatment of Ovarian Cancer., PMID:39594628
Combination therapy of Sanjie Zhentong capsules for endometriosis: Impact on hormone regulation and serum expression of FOLR1 and MSLN., PMID:39465861
Safety and tolerability of mirvetuximab soravtansine monotherapy for folate receptor alpha-expressing recurrent ovarian cancer: An integrated safety summary., PMID:39461270
Assessment of mirvetuximab soravtansine immunogenicity in patients with folate receptor alpha-positive ovarian cancer., PMID:39378056
Characterizing the genomic landscape through the lens of FOLR1 status in low and high grade serous ovarian carcinoma., PMID:39366033
A specific folate activates serotonergic neurons to control C. elegans behavior., PMID:39349491
Accumulation of Cerebrospinal Fluid, Ventricular Enlargement, and Cerebral Folate Metabolic Errors Unify a Diverse Group of Neuropsychiatric Conditions Affecting Adult Neocortical Functions., PMID:39337690
Exposure-response relationships of mirvetuximab soravtansine in patients with folate receptor-α-positive ovarian cancer: Justification of therapeutic dose regimen., PMID:39307840
Regulation of gene expression in milk secretory pathways during secretory activation in Holstein cows., PMID:39245162
Alteration in folate carrier expression via histone deacetylase inhibition in BeWo human placental choriocarcinoma cells., PMID:39237058
CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target., PMID:39145456
PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis., PMID:39085882
Vaccination with folate receptor-alpha peptides in patients with ovarian cancer following response to platinum-based therapy: A randomized, multicenter clinical trial., PMID:39068739
Investigation of the synergistic effect mechanism underlying sequential use of palbociclib and cisplatin through integral proteomic and glycoproteomic analysis., PMID:39011652
Folate receptor alpha expression in low-grade serous ovarian cancer: Exploring new therapeutic possibilities., PMID:38941962
Expression of the Folate Receptor Proteins FOLR1 and FOLR2 in Correlation With Clinicopathological Variables of Gastric Cancer., PMID:38915965
Folate Receptor Immunohistochemical Staining and Gynecologic Tumors: Initial Experience With 216 Cases., PMID:38914019
Folate Receptor Alpha Expression and the Tumor Immune Microenvironment in Patients with Cervical Cancer., PMID:38914017
Folate receptor alpha protein expression in ovarian serous cystadenocarcinoma tumors of The Cancer Genome Atlas: exploration beyond single-agent therapy., PMID:38645083
Role of folate receptor α in the partial rejuvenation of dentate gyrus cells: Improvement of cognitive function in 21-month-old aged mice., PMID:38519576
Exosomal or follicular FNDC3A decreases FOLR1 mRNA abundance and progesterone and lactate synthesis in bovine granulosa cells., PMID:38513348
Developing Folate-Conjugated miR-34a Therapeutic for Prostate Cancer: Challenges and Promises., PMID:38396800
Noncanonical function of folate through folate receptor 1 during neural tube formation., PMID:38388461
Development of an FRα Companion Diagnostic Immunohistochemical Assay for Mirvetuximab Soravtansine., PMID:38282564
Folate Receptor Alpha-A Novel Approach to Cancer Therapy., PMID:38256120
For research use only. Not for human or drug use.
