Catalog No.
YHD00301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Cys172
Predicted molecular weight
21.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13693
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Histamine-releasing factor, TPT1, HRF, Translationally-controlled tumor protein, TCTP, p23, Fortilin
The Translationally Controlled Tumor Protein (TCTP), a Novel Antigen of Babesia bovis, Participates in the Establishment of Acute Infection and Contains Neutralizing B-Cell Epitopes., PMID:40430821
Immune inflammatory regulation in Anti-NMDAR encephalitis: insights from transcriptome analysis., PMID:40417115
Translationally controlled tumor protein GmTCTP2 positively regulates plant drought tolerance through GmSCEc mediated SUMOylation., PMID:40339855
Lnc-TPT1-AS1/CBP/ATIC Axis Mediated Purine Metabolism Activation Promotes Breast Cancer Progression., PMID:40091780
Blood TCTP as a potential biomarker associated with immunosuppressive features and poor clinical outcomes in metastatic gastric cancer., PMID:40032602
Hypoxia-induced PRPF19 modulates TPT1 alternative splicing to facilitate cisplatin resistance in high-grade serous ovarian cancer., PMID:39983558
Helicobacter pylori SlyD stabilizes TPT1 via hnRNPK and enhances OCT1-mediated CDX2 transcriptional activation to drive gastric intestinal metaplasia., PMID:39915880
Intranasal insulin administration affecting perioperative neurocognitive dysfunction by regulating calcium transport protein complex IP3R/GRP75/VDAC1 on MAMs., PMID:39761768
Analyzing the functions of Translationally controlled tumor protein2 during growth, development and autophagy of Dictyostelium discoideum., PMID:39753197
Plasma Proteomics of Type 2 Diabetes, Hypertension, and Co-Existing Diabetes/Hypertension in Thai Adults., PMID:39459569
Cell Fate Dynamics Reconstruction Identifies TPT1 and PTPRZ1 Feedback Loops as Master Regulators of Differentiation in Pediatric Glioblastoma-Immune Cell Networks., PMID:39420135
The multifaceted potential of TPT1 as biomarker and therapeutic target., PMID:39397949
Proteomic profiling of cerebrospinal fluid reveals TKT as a potential biomarker for medulloblastoma., PMID:39251709
Therapeutic efficacy of JEW-M449, an anti-TCTP monoclonal antibody, administered via the nasal route in a BALB/c mouse model of ovalbumin-induced acute asthma., PMID:39226728
Translationally controlled tumor protein interacts with TaCIPK23 to positively regulate wheat resistance to Puccinia triticina., PMID:39180235
Long non-coding RNA TPT1-AS1 inhibits ferroptosis in ovarian cancer by regulating GPX4 via CREB1 regulation., PMID:39141012
Towards effective CAIX-targeted radionuclide and checkpoint inhibition combination therapy for advanced clear cell renal cell carcinoma., PMID:38948062
The lncRNA TPT1-AS1 promotes the survival of neuroendocrine prostate cancer cells by facilitating autophagy., PMID:38859837
The TCTP is essential for ovarian development and oviposition of Rhipicephalus haemaphysaloides., PMID:38781831
Cucumber (Cucumis sativus L.) translationally controlled tumor protein interacts with CsRab11A and promotes activation of target of rapamycin in response to Podosphaera xanthii., PMID:38700955
AI-based Virtual Screening of Traditional Chinese Medicine and the Discovery of Novel Inhibitors of TCTP., PMID:38310576
Targeting inhibition of TCTP could inhibit proliferation and induce apoptosis in AML cells., PMID:38309549
Expression profile analysis of LncRNAs and mRNAs in pre-receptive endometrium of women with polycystic ovary syndrome undergoing in vitro fertilization-embryo transfer., PMID:38243290
Enhanced Tumor Targeting of Radiolabeled Mouse/Human Chimeric Anti-Tn Antibody in Losartan-Treated Mice Bearing Tn-Expressing Lung Tumors., PMID:38215243
Unveiling dysregulated lncRNAs and networks in non-syndromic cleft lip with or without cleft palate pathogenesis., PMID:38200098
A tryptophan-based assay method to search regulatory compounds for transcriptionally controlled tumor protein., PMID:38071892
Identification of key genes in sepsis-induced cardiomyopathy based on integrated bioinformatical analysis and experiments in vitro and in vivo., PMID:38025678
Targeting the translationally controlled tumor protein by a monoclonal antibody improves allergic airway inflammation in mice., PMID:37806090
Elevated translationally controlled tumour protein promotes oral cancer progression and poor outcome., PMID:37573872
Sertraline as a potential cancer therapeutic approach: Biological relevance of TCTP in breast cancer cell lines and tumors., PMID:37379765
Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation., PMID:37334830
Structural transitions in TCTP tumor protein upon binding to the anti-apoptotic protein family member Mcl-1., PMID:37201583
Inhibitors of dimerized translationally controlled tumor protein, a histamine releasing factor, may serve as anti-allergic drug candidates., PMID:36963558
Translationally controlled tumor protein restores impaired memory and altered synaptic protein expression in animal models of dementia., PMID:36738496
METTL13 promotes nasopharyngeal carcinoma progression through regulating the ZEB1/TPT1 axis., PMID:36735630
Does translationally controlled tumor protein (TCTP) have the potential to produce crops with increased growth and tolerance to environmental stresses?, PMID:36723675
Polymorphisms in TPT1 Pathways in Pediatric Astrocytomas., PMID:36714975
Meclizine, a piperazine-derivative antihistamine, binds to dimerized translationally controlled tumor protein and attenuates allergic reactions in a mouse model., PMID:36493627
Histamine-Releasing Factor Is a Novel Alarmin Induced by House Dust Mite Allergen, Cytokines, and Cell Death., PMID:36426937
Effects of Sarcoptes scabiei Translationally Controlled Tumor Protein (TCTP) on Histamine Release and Degranulation of KU812 Cells., PMID:36361656
A review of literature: role of long noncoding RNA TPT1-AS1 in human diseases., PMID:36112261
Protein transduction domain of translationally controlled tumor protein: characterization and application in drug delivery., PMID:36104954
Long-Term Effect of Modified Glass Ionomer Cement with Mimicked Biological Property of Recombinant Translationally Controlled Protein., PMID:36015596
Translationally controlled tumor protein: the mediator promoting cancer invasion and migration and its potential clinical prospects., PMID:35953758
PEGylation improves the therapeutic potential of dimerized translationally controlled tumor protein blocking peptide in ovalbumin-induced mouse model of airway inflammation., PMID:35850571
Dimeric translationally controlled tumor protein-binding peptide 2 attenuates imiquimod-induced psoriatic inflammation through induction of regulatory T cells., PMID:35689858
TPT1 Supports Proliferation of Neural Stem/Progenitor Cells and Brain Tumor Initiating Cells Regulated by Macrophage Migration Inhibitory Factor (MIF)., PMID:35622214
Translationally Controlled Tumor Protein-Mediated Stabilization of Host Antiapoptotic Protein MCL-1 Is Critical for Establishment of Infection by Intramacrophage Parasite Leishmania donovani., PMID:35562118
Positive feedback regulation of lncRNA TPT1-AS1 and ITGB3 promotes cell growth and metastasis in pancreatic cancer., PMID:35534983
Overexpression of IncRNA TPT1-AS1 Suppresses Hepatocellular Carcinoma Cell Proliferation by Downregulating CDK2., PMID:35377976
For research use only. Not for human or drug use.
