Catalog No.
RHH35001
Species reactivity
Human, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, WB: 1:500-1:1000
Target
CYPIB1, Cytochrome P450 1B1, Hydroperoxy icosatetraenoate dehydratase, CYP1B1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q16678
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2H45
Unveiling compositional images of specific proteins in individual cells by LA-ICP-MS: Labelling with ruthenium red and metal nanoclusters., PMID:39030007
Evaluation of CYP1B1, oxidative stress and phase II detoxification enzyme status in oral cancer progression model., PMID:38384675
A pH-responsive cetuximab-conjugated DMAKO-20 nano-delivery system for overcoming K-ras mutations and drug resistance in colorectal carcinoma., PMID:38331131
Lactobacillus species ameliorate membranous nephropathy through inhibiting the aryl hydrocarbon receptor pathway via tryptophan-produced indole metabolites., PMID:37594378
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer., PMID:37059712
CYP1B1-catalyzed 4-OHE2 promotes the castration resistance of prostate cancer stem cells by estrogen receptor α-mediated IL6 activation., PMID:35292057
Prenatal diagnosis of primary congenital glaucoma and histopathological features in a fetal globe with cytochrome p4501B1 mutations., PMID:34730456
Neurons expressing the aryl hydrocarbon receptor in the locus coeruleus and island of Calleja major are novel targets of dioxin in the mouse brain., PMID:33963922
Prenatal indole-3-carbinol administration activates aryl hydrocarbon receptor-responsive genes and attenuates lung injury in a bronchopulmonary dysplasia model., PMID:33148012
Cytochrome P450 1B1 polymorphism drives cancer cell stemness and patient outcome in head-and-neck carcinoma., PMID:32565541
Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium., PMID:31616008
Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells., PMID:30372497
Roles of Aryl Hydrocarbon Receptor in Aromatase-Dependent Cell Proliferation in Human Osteoblasts., PMID:29039776
CXCR4 promotes cisplatin-resistance of non-small cell lung cancer in a CYP1B1-dependent manner., PMID:27922681
Functional characterization of eight rare missense CYP1B1 variants involved in congenital glaucoma and their association with null genotypes., PMID:27060699
Role of aryl hydrocarbon receptor polymorphisms on TCDD-mediated CYP1B1 induction and IgM suppression by human B cells., PMID:27535091
The serotonin transporter promotes a pathological estrogen metabolic pathway in pulmonary hypertension via cytochrome P450 1B1., PMID:27162617
The p.Gly61Glu Mutation in CYP1B1 Affects the Extracellular Matrix in Glaucoma Patients., PMID:26982174
Preferential expression of cytochrome CYP CYP2R1 but not CYP1B1 in human cord blood hematopoietic stem and progenitor cells., PMID:26579418
Aryl Hydrocarbon Receptor Protects Lungs from Cockroach Allergen-Induced Inflammation by Modulating Mesenchymal Stem Cells., PMID:26561548
Enzymatic characterization of in vitro-expressed Baikal seal cytochrome P450 (CYP) 1A1, 1A2, and 1B1: implication of low metabolic potential of CYP1A2 uniquely evolved in aquatic mammals., PMID:25814058
The catecholestrogen, 2-hydroxyestradiol-17beta, acts as a G protein-coupled estrogen receptor 1 (GPER/GPR30) antagonist to promote the resumption of meiosis in zebrafish oocytes., PMID:25609836
3, 3'-Diindolylmethane alleviates steatosis and the progression of NASH partly through shifting the imbalance of Treg/Th17 cells to Treg dominance., PMID:25281898
Paradoxic effects of metformin on endothelial cells and angiogenesis., PMID:24419232
Expression profile of CYP1A1 and CYP1B1 enzymes in colon and bladder tumors., PMID:24358191
Modulation of benzo[a]pyrene induced neurotoxicity in female mice actively immunized with a B[a]P-diphtheria toxoid conjugate., PMID:23684556
Targeted multiplex imaging mass spectrometry with single chain fragment variable (scfv) recombinant antibodies., PMID:22869296
Induction of intracellular calcium concentration by environmental benzo(a)pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1,4,5-trisphosphate pathway in endothelial cells., PMID:22167199
Immunoglobulin light chain, Blimp-1 and cytochrome P4501B1 peptides as potential vaccines for AL amyloidosis., PMID:21894172
Effects of PCB126 and 17β-oestradiol on endothelium-derived vasoactive factors in human endothelial cells., PMID:21513769
Complex genetic mechanisms in glaucoma: an overview., PMID:21150032
Estradiol-17beta and its cytochrome P450- and catechol-O-methyltransferase-derived metabolites stimulate proliferation in uterine artery endothelial cells: role of estrogen receptor-alpha versus estrogen receptor-beta., PMID:20212268
Expression and induction of cytochrome p450 isoenzymes in human skin equivalents., PMID:20090406
Modulation of benzo[a]pyrene induced immunotoxicity in mice actively immunized with a B[a]P-diphtheria toxoid conjugate., PMID:19573549
In vitro studies on the metabolism of trabectedin (YONDELIS) in monkey and man, including human CYP reaction phenotyping., PMID:19426702
Severe molecular defects of a novel FOXC1 W152G mutation result in aniridia., PMID:19279310
Effects of dioxin on vascular endothelial growth factor (VEGF) production in the retina associated with choroidal neovascularization., PMID:19182260
Lineage restriction and differentiation of human embryonic stem cells into hepatic progenitors and zone 1 hepatocytes., PMID:19063660
Targeting cytochrome P450 CYP1B1 with a therapeutic cancer vaccine., PMID:18767949
The effect of initiating doses of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene on the expression of PAH activating enzymes and its modulation by plant phenols., PMID:18694800
Cytochrome P450 1B1 expression in rat esophageal tumorigenesis promoted by gastric and duodenal reflux., PMID:18618592
Methoxychlor and estradiol induce oxidative stress DNA damage in the mouse ovarian surface epithelium., PMID:18502743
CYP1B1 is not a major determinant of the disposition of aromatase inhibitors in epithelial cells of invasive ductal carcinoma., PMID:18256205
Drug metabolism enzyme expression and activity in primary cultures of human proximal tubular cells., PMID:18055091
Embryonic expression of the optineurin (glaucoma) gene in different stages of mouse development., PMID:17893645
Microsomal expoxide hydrolase is required for 7,12-dimethylbenz[a]anthracene (DMBA)-induced immunotoxicity in mice., PMID:17442664
Tocopherol transfer protein deficiency modifies nuclear receptor transcriptional networks in lungs: modulation by cigarette smoke in vivo., PMID:17400288
Molecular characterization of cytochrome P450 1A1, 1A2, and 1B1, and effects of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners on their hepatic expression in Baikal seal (Pusa sibirica)., PMID:17383972
Recombinant antibody piezoimmunosensors for the detection of cytochrome P450 1B1., PMID:17297925
CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime]., PMID:16997912
For research use only. Not for human or drug use.
