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Anti-CYP4A11 Antibody (R2C28)

Catalog #:   RHF96601 Specific References (25) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IHC, IP, WB
Accession: Q02928
Overview

Catalog No.

RHF96601

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000

Target

Cytochrome P450HL-omega, 20-hydroxyeicosatetraenoic acid synthase, Long-chain fatty acid omega-monooxygenase, Fatty acid omega-hydroxylase, Cytochrome P450 4A11, Lauric acid omega-hydroxylase, CYP4A2, CYP4AII, CYP4A11, CYPIVA11, 20-HETE synthase, Cytochrome P-450HK-omega

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q02928

Applications

IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2C28

Data Image
  • Western blot
    Western blot analysis of Cytochrome P450 4A expression in Human fetal kidney lysate.
References

New genetic variations discovered in KRAS wild-type cetuximab resistant chinese colorectal cancer patients., PMID:32141150

A Specific Probe Substrate for Evaluation of CYP4A11 Activity in Human Tissue Microsomes and a Highly Selective CYP4A11 Inhibitor: Luciferin-4A and Epalrestat., PMID:29976573

The differential expression of omega-3 and omega-6 fatty acid metabolising enzymes in colorectal cancer and its prognostic significance., PMID:28557975

Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine., PMID:25138712

20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo., PMID:24403517

Expression of CYP2A6, CYP2D6 and CYP4A11 Polymorphisms in COS7 Mammalian Cell Line., PMID:24278547

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11., PMID:18065749

Drug metabolism enzyme expression and activity in primary cultures of human proximal tubular cells., PMID:18055091

Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine., PMID:17709372

Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype., PMID:16945988

Catalytic assays for human cytochrome P450: an introduction., PMID:16719375

Cloning and expression of koala (Phascolarctos cinereus) liver cytochrome P450 CYP4A15., PMID:16677781

Catalytic Assays for Human Cytochrome P450 : An Introduction., PMID:27699679

Induction of cytochrome P450 enzymes in cultured precision-cut human liver slices., PMID:12584154

Associations between human liver and kidney cadmium content and immunochemically detected CYP4A11 apoprotein., PMID:11992637

Cytochrome P450 4A11 expression in human keratinocytes: effects of ultraviolet irradiation., PMID:11736898

Metabolism of a disulfiram metabolite, S-methyl N,N-diethyldithiocarbamate, by flavin monooxygenase in human renal microsomes., PMID:11159801

Differential maintenance of cytochrome P450 enzymes in cultured precision-cut human liver slices., PMID:10997941

Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11., PMID:10660572

Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4., PMID:9799565

Development of a comprehensive panel of antibodies against the major xenobiotic metabolising forms of cytochrome P450 in humans., PMID:9744576

Metabolism of arachidonic acid to 20-hydroxy-5,8,11, 14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11., PMID:9618440

Characterization of cytochrome P450 enzymes in human breast tissue from reduction mammaplasties., PMID:9506744

Role of CYP2D6 in the N-hydroxylation of procainamide., PMID:9352574

Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes., PMID:8914854

Datasheet
$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-CYP4A11 Antibody (R2C28) [RHF96601]
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