Catalog No.
EHC25201
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Glu512
Predicted molecular weight
57.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P07333
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD115, CSF-1 receptor, CSF1R, M-CSF-R, CSF-1-R, Proto-oncogene c-Fms, Macrophage colony-stimulating factor 1 receptor, CSF-1R, FMS
RACK1 promotes the development and function of alveolar macrophages through directly binding to and stabilizing PPARγ., PMID:40512793
Pancreatic cancer cell-intrinsic transglutaminase-2 promotes T cell suppression through microtubule-dependent secretion of immunosuppressive cytokines., PMID:40447317
Preconditioning with Rapamycin Improves Therapeutic Potential of Placenta-Derived Mesenchymal Stem Cells in Mouse Model of Hematopoietic Acute Radiation Syndrome., PMID:40429945
The mycotoxin Beauvericin is an uncompetitive inhibitor of Cathepsin B., PMID:40411408
Engineered Mycobacterium smegmatis expressing anti-PD-L1/IL-15 immunocytokine induces and activates specific antitumor immunity., PMID:40404207
NLRP3 regulates macrophage function by M-CSF/M-CSFR signaling in acute radiation-induced lung injury., PMID:40403643
Generation of Human Monocyte-Derived Immunogenic Dendritic Cells via mTORC1 and PPARγ Inhibition., PMID:40402460
Modeling hereditary diffuse leukoencephalopathy with axonal spheroids using microglia-sufficient brain organoids., PMID:40397490
Assessment of a salivary cfRNA biomarker panel to predict preeclampsia., PMID:40393217
Apoptosis inhibitor of macrophage suppress immune responses via IL-10 production and delay bacterial clearance in Mycobacterium avium infection., PMID:40391046
Genomic and transcriptomic determinants of clinical outcomes in patients with AML and DNMT3A mutations., PMID:40389402
Rationale and feasibility of a rapid integral biomarker program that informs immune-oncology clinical trials: the ADVISE trial., PMID:40389374
CSF1R ligands promote microglial proliferation but are not the sole regulators of developmental microglial proliferation., PMID:40387575
Seasonal Proteomic Variations and Biomarkers in Seasonal Allergic Rhinitis: Insights from Olink Inflammation Profiling., PMID:40386182
Characterization of IL-34 and CSF-1R in Sciaenops ocellatus: IL-34 participates in its anti-bacterial immune responses to Vibrio harveyi infection., PMID:40383499
Cellular effects of splenectomy on liver regeneration after 70% resection., PMID:40376613
Identification of 1,400 metabolites as mediators of obesity in 473 gut microbiota taxa: a mediation Mendelian randomization study., PMID:40372036
Integration of Bioinformatics and Machine Learning Strategies Identifies Ferroptosis and Immune Infiltration Signatures in Peri-Implantitis., PMID:40362543
Multiplatform molecular analyses reveal two molecular subgroups of NF2-related schwannomatosis vestibular schwannomas with distinct tumour microenvironment and therapeutic vulnerabilities., PMID:40343504
Evaluating Axatilimab as a treatment option for chronic graft-versus-host disease., PMID:40338737
Interleukin-34-dependent perivascular macrophages promote vascular function in the brain., PMID:40315842
Brain-wide microglia replacement using a nonconditioning strategy ameliorates pathology in mouse models of neurological disorders., PMID:40305572
Genomic analysis of progenitors in viral infection implicates glucocorticoids as suppressors of plasmacytoid dendritic cell generation., PMID:40294270
Inhibition of LPL suppresses the osteoclast differentiation of bone-marrow-derived macrophages by promoting the ACSL4 ubiquitination., PMID:40273672
Targeting oncogenic activation of FLT3/SREBP/FASN promotes the therapeutic effect of quizartinib involving disruption of mitochondrial phospholipids., PMID:40263296
Systematic Review of Relevant Biomarkers for Human Connective Tissue Repair and Healing Outcome: Implications for Understanding Healing Processes and Design of Healing Interventions., PMID:40248898
Aldosterone-Induced Transformation of Vascular Smooth Muscle Cells into Macrophage-like Cells Participates in Inflammatory Vascular Lesions., PMID:40244230
Matrix Metalloproteinase-9 Enhances Osteoclastogenesis: Insights from Transgenic Rabbit Bone Marrow Models and In Vitro Studies., PMID:40244002
Soluble-microneedle enhance three T-cell activation signals as efficient tumor vaccines for melanoma prevention and treatment., PMID:40233828
Fibroblast to macrophage-like cell transition in renal inflammatory injury through the MR/CSF1 pathway induced by aldosterone., PMID:40216224
Early Growth Response 1 Plays an Essential Role in Proinflammatory and Osteoclastogenic Activities of Lipopolysaccharide-Stimulated Osteoblasts., PMID:40193242
Assessment of chromatin remodeling of acute myeloid leukemia cells treated with gilteritinib: a case report., PMID:40181449
Do the monocyte-derived dendritic cells exert a pivotal role in the early onset of experimental autoimmune uveitis?, PMID:40175949
Association of the ADRB2 rs1042714 variant with retinopathy of prematurity highlights the importance of the renin-angiotensin-aldosterone system., PMID:40175432
Protein succinylome analysis identifies citrate synthase as a central regulator of osteoclast metabolic activity., PMID:40172090
Ultrasensitive Detection of FLT3-ITD Mutations via Primer Competition Enhanced Mutant Accumulation., PMID:40162954
Resident Macrophages in the Cervical Sympathetic Ganglia Participate in P2Y12 Receptor Mediated Diabetic Cardiac Autonomic Neuropathy., PMID:40146499
Pharmacological Inhibition of Microglial Proliferation Supports Blood-Brain Barrier Integrity in Experimental Autoimmune Encephalomyelitis., PMID:40136663
Unveiling causal pathways in autoimmune diseases: a multi-omics approach., PMID:40135285
Decreased Extracellular Vesicle Vasorin in Severe Preeclampsia Plasma Mediates Endothelial Dysfunction., PMID:40118804
Neuro-Immuno-Endocrine Regulation of Bone Homeostasis., PMID:40116095
Mitigation and Management of Common Toxicities Associated with the Administration of CAR-T Therapies in Oncology Patients., PMID:40108072
Bordetella adenylate cyclase toxin elicits chromatin remodeling and transcriptional reprogramming that blocks differentiation of monocytes into macrophages., PMID:40105369
New soluble CSF-1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in pleural mesothelioma., PMID:40101804
Effect of FLT3 ligand on the gene expression of TIM-3, HIF1-α, and TNF-α in an acute myeloid leukemia cell line., PMID:40085277
Interleukin-34 orchestrates bone formation through its binding to bone morphogenic proteins., PMID:40083929
Centripetal migration and prolonged retention of microglia promotes spinal cord injury repair., PMID:40075472
Burn injury-induced G-CSF secretion reduces spic+ erythroblastic island macrophages in the bone marrow and impairs medullary erythropoiesis., PMID:40073238
Expansion and pathogenic activation of skeletal muscle-resident macrophages in mdx5cv/Ccr2-/- mice., PMID:40067893
LILRB4 specific overexpression in myeloid cells promotes tumor progression and immunosuppression in mouse models., PMID:40048761
For research use only. Not for human or drug use.
