Anti-ULK1 Antibody (R1F26)

Catalog No.

RHB18102

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

ULK1, Autophagy-related protein 1 homolog, Unc-51-like kinase 1, KIAA0722, Serine/threonine-protein kinase ULK1, hATG1, ATG1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O75385

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1F26

miRNA-29b-3p: An Important Target for Ameliorating Liver Fibrosis in Wilson Disease by Inhibiting Autophagy., PMID:40375700

Mechanistic Insights Into GDFMD-Mediated Inhibition of Liver Fibrosis via miRNA-29b-3p Upregulation in Wilson's Disease., PMID:40322065

Targeting autophagy in autoimmune glomerular diseases., PMID:40106213

The potential role of RhoA/ROCK-inhibition on locomotor recovery after spinal cord injury: a systematic review of in-vivo studies., PMID:39956860

MEHP induced mitochondrial damage by promoting ROS production in CIK cells, leading to apoptosis, autophagy, cell cycle arrest., PMID:39586385

Autophagy Blockage Up-Regulates HLA-Class-I Molecule Expression in Lung Cancer and Enhances Anti-PD-L1 Immunotherapy Efficacy., PMID:39409895

Uncovering the connection between obesity and thyroid cancer: the therapeutic potential of adiponectin receptor agonist in the AdipoR2-ULK axis., PMID:39349421

PRRSV utilizes MALT1-regulated autophagy flux to switch virus spread and reserve., PMID:39081059

Protective effect of modified Huangqi Chifeng decoction on immunoglobulin A nephropathy through toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-kappa B signaling pathway., PMID:38504538

Fasting-Mimicking Diet Inhibits Autophagy and Synergizes with Chemotherapy to Promote T-Cell-Dependent Leukemia-Free Survival., PMID:38136414

Rigosertib promotes anti-tumor immunity via autophagic degradation of PD-L1 in colorectal cancer cells., PMID:37805162

Epigallocatechin-3-Gallate, an Active Green Tea Component to Support Anti-VEGFA Therapy in Wet Age-Related Macular Degeneration., PMID:37571296

Phosphorylation of pICln by the autophagy activating kinase ULK1 regulates snRNP biogenesis and splice activity of the cell., PMID:36968021

Association of ATG7 gene polymorphisms with microscopic polyangiitis in Chinese individuals., PMID:36398269

Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy., PMID:36334887

Tumor-derived CTF1 (cardiotrophin 1) is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis., PMID:35722965

Mechanisms in Graves Eye Disease: Apoptosis as the End Point of Insulin-Like Growth Factor 1 Receptor Inhibition., PMID:34927457

Autophagy-related Prognostic Signature in HER2 Positive Gastric Carcinomas., PMID:34814818

Rescue of thyroid cells from antibody induced cell death via induction of autophagy., PMID:34801870

Punicalagin, a pomegranate compound, induces apoptosis and autophagy in acute leukemia., PMID:34760363

TFG binds LC3C to regulate ULK1 localization and autophagosome formation., PMID:33932238

Bioactive peptide isolated from sesame seeds inhibits cell proliferation and induces apoptosis and autophagy in leukemic cells., PMID:33907539

The BAX-binding protein MOAP1 associates with LC3 and promotes closure of the phagophore., PMID:33783314

Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1G93A astrocytes., PMID:33749521

Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism., PMID:33749503

PCR Array Technology in Biopsy Samples Identifies Up-Regulated mTOR Pathway Genes as Potential Rejection Biomarkers After Kidney Transplantation., PMID:33681239

Anti-Na+/K+-ATPase immunotherapy ameliorates α-synuclein pathology through activation of Na+/K+-ATPase α1-dependent autophagy., PMID:33571110

The relationship between the mTOR signaling pathway and ovarian aging in peak-phase and late-phase laying hens., PMID:33357698

Autophagy and apoptosis induction by sesamin in MOLT-4 and NB4 leukemia cells., PMID:33262824

Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles., PMID:33060596

Vitamin D - A host directed autophagy mediated therapy for tuberculosis., PMID:33039674

Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs., PMID:33034545

Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System., PMID:32668203

ULK1-ATG13 and their mitotic phospho-regulation by CDK1 connect autophagy to cell cycle., PMID:32516310

Autophagy coupled to translation is required for long-term memory., PMID:32501746

The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses., PMID:32249716

(Curcumin+sildenafil) enhances the efficacy of 5FU and anti-PD1 therapies in vivo., PMID:31985048

GZ17-6.02 initiates DNA damage causing autophagosome-dependent HDAC degradation resulting in enhanced anti-PD1 checkpoint inhibitory antibody efficacy., PMID:31951027

TGF-β1 inhibits the autophagy of podocytes by activating mTORC1 in IgA nephropathy., PMID:31600491

Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunity Is Defined by Intracellular TRIM21-Dependent Innate Immune Activation and Extracellular Neutralization., PMID:31548319

The immunomodulatory functions and molecular mechanism of a new bursal heptapeptide (BP7) in immune responses and immature B cells., PMID:31533803

Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits., PMID:31234698

Unconventional Secretion of Adipocyte Fatty Acid Binding Protein 4 Is Mediated By Autophagic Proteins in a Sirtuin-1-Dependent Manner., PMID:31171562

Disrupted apolipoprotein L1-miR193a axis dedifferentiates podocytes through autophagy blockade in an APOL1 risk milieu., PMID:31116585

Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392

The Functions and Mechanism of a New Oligopeptide BP9 from Avian Bursa on Antibody Responses, Immature B Cell, and Autophagy., PMID:30723747

Identification of New Potential Therapies for Colitis Amelioration Using an Appendicitis-Appendectomy Model., PMID:30329049

RB1CC1-enhanced autophagy facilitates PSCs activation and pancreatic fibrogenesis in chronic pancreatitis., PMID:30237496

ATG5 is required for B cell polarization and presentation of particulate antigens., PMID:30196744

Butein Activates Autophagy Through AMPK/TSC2/ULK1/mTOR Pathway to Inhibit IL-6 Expression in IL-1β Stimulated Human Chondrocytes., PMID:30184535

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