Catalog No.
RHA14801
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Applications
WB
Recommended Dilution
| Application |
Dilution |
| WB |
1:500-1:1000 |
Target
Krev interaction trapped protein 1, Cerebral cavernous malformations 1 protein, Krev interaction trapped 1, CCM1, KRIT1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O00522
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1C98
Note
For research use only.
Hereditary intraosseous vascular malformation of the craniofacial region: an apparently novel disorder., PMID:11932989
KRIT1, a gene mutated in cerebral cavernous malformation, encodes a microtubule-associated protein., PMID:12140362
KRIT1/cerebral cavernous malformation 1 protein localizes to vascular endothelium, astrocytes, and pyramidal cells of the adult human cerebral cortex., PMID:15046662
CCM2 expression parallels that of CCM1., PMID:16373645
Proteomic identification of the cerebral cavernous malformation signaling complex., PMID:17900104
KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions., PMID:17954608
Ultrastructural analysis of vascular features in cerebral cavernous malformations., PMID:22776801
Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation., PMID:27548575
The CCM1-CCM2 complex controls complementary functions of ROCK1 and ROCK2 that are required for endothelial integrity., PMID:30030370
Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice., PMID:30442679
Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice., PMID:32068019
Detection of p62/SQSTM1 Aggregates in Cellular Models of CCM Disease by Immunofluorescence., PMID:32524569
Fluorescence Analysis of Reactive Oxygen Species (ROS) in Cellular Models of Cerebral Cavernous Malformation Disease., PMID:32524573
β1 integrin monoclonal antibody treatment ameliorates cerebral cavernous malformations., PMID:36349990
Magnetic Resonance Imaging of Mouse Cerebral Cavernomas Reveal Differential Lesion Progression and Variable Permeability to Gadolinium., PMID:37078284
For research use only. Not for human or drug use.
