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Canrenone/CRN, OVA conjugated

Catalog #:   SGK61516 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB
Accession: 976-71-6
Overview

Catalog No.

SGK61516

Species

General

Endotoxin level

Please contact with the lab for this information.

Accession

976-71-6

Applications

ELISA, Immunogen, SDS-PAGE, WB

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

phanurane;pregna-4,6-diene-21-carboxylicacid,17-hydroxy-3-oxo-,gamma-lactone,(17-alph;sc9376;spirolactonesc14266;CANRENOICACIDGAMMALACTONE;CANRENONE;CANRENONE-D4;4,6-ANDROSTADIEN[(17(B-1')-SPIRO-5')]-PERHYDROFURAN-2,3-DIONE

Data Image
References

Model-Informed Dose Optimization of Spironolactone in Neonates and Infants., PMID:40143132

Mineralocorticoid Receptor Antagonism Reduces Atrial Arrhythmias Post-Cardiac Surgery and Attenuates Atrial Stress Responses to Cardioplegic Arrest., PMID:40060465

Dose-exposure-response of CARDALIS® (benazepril/spironolactone) on the classical and alternative arms of the renin-angiotensin-aldosterone system in healthy dogs., PMID:39601373

Association between mineralocorticoid receptor antagonists and kidney harm: A systematic review and meta-analysis of randomized controlled trials., PMID:39578707

Untargeted metabolomics to detect and identify plasma metabolic signatures associated with intracranial aneurysm and its rupture., PMID:39549086

Marine Bacillus pumilus substances exhibit antimicrobial effect on multidrug-resistant Staphylococcus aureus., PMID:39401988

Endogenous bufadienolides, mineralocorticoid receptor antagonists and fibrosis in chronic kidney disease., PMID:39295945

Allergic Contact Dermatitis to Topical Preparations Containing Minoxidil: A Systematic Review and Individual Participant Data Meta-Analysis., PMID:38885151

Mineralocorticoid receptor antagonists in heart failure with reduced ejection fraction: a systematic review and network meta-analysis of 32 randomized trials., PMID:38692445

Spironolactone metabolite causes falsely increased progesterone in the Abbott Architect immunoassay., PMID:38484829

Comprehensive characterization of the effect of mineralocorticoid receptor antagonism with spironolactone on the renin-angiotensin-aldosterone system in healthy dogs., PMID:38394253

Probing the hair detectability of prohibited substances in sports: an in vivo-in silico-clinical approach and analytical implications compared with plasma, urine, and faeces., PMID:38224356

Water and Electrolyte Content in Salt-Dependent HYpertension in the SKIn (WHYSKI): Effect of Surgical Cure of Primary Aldosteronism., PMID:38123759

Eco-friendly solvent bar microextraction based on a natural deep eutectic solvent and multivariate optimization for simultaneous determination of spironolactone and canrenone in urine and plasma samples., PMID:38079037

Pharmacokinetics of oral spironolactone in infants up to 2 years of age., PMID:38041740

Endogenous Digitalis-like Factors as a Key Molecule in the Pathophysiology of Pregnancy-Induced Hypertension and a Potential Therapeutic Target in Preeclampsia., PMID:37628922

Estradiol and Spironolactone Plasma Pharmacokinetics Among Brazilian Transgender Women Using HIV Pre-Exposure Prophylaxis: Analysis of Potential Interactions., PMID:37261664

An Indonesian slimming drug with undeclared ingredients causing harm., PMID:36808870

Exploration of sodium homeostasis and pharmacokinetics in bile duct-ligated rats treated by anti-cirrhosis herbal formula plus spironolactone., PMID:36744253

Novel approach to adherence assessment based on parent drug and metabolite pharmacokinetics: pilot study with spironolactone., PMID:36472169

Spontaneous Remission of Primary Aldosteronism with Mineralocorticoid Receptor Antagonist Therapy: A Review., PMID:36430298

Closing the gap - development of an analytical methodology using volumetric absorptive microsampling of finger prick blood followed by LC-HRMS/MS for adherence monitoring of antihypertensive drugs., PMID:36318313

Activation of RAAS Signaling Contributes to Hypertension in Aged Hyp Mice., PMID:35884995

Development of UHPLC-MS/MS methods to quantify 25 antihypertensive drugs in serum in a cohort of patients treated for hypertension., PMID:35803015

Engineering of a fungal steroid 11α-hydroxylase and construction of recombinant yeast for improved production of 11α-hydroxyprogesterone., PMID:35654275

Association between Mineralocorticoid Receptor Antagonist and Mortality in SARS-CoV-2 Patients: A Systematic Review and Meta-Analysis., PMID:35455823

Adherence and blood pressure control in patients with primary aldosteronism., PMID:35438025

Canrenone Restores Vasorelaxation Impaired by Marinobufagenin in Human Preeclampsia., PMID:35328757

Sex Differences in Spironolactone and the Active Metabolite Canrenone Concentrations and Adherence., PMID:35052816

Topical Treatment of Human Skin and Cultured Keratinocytes with High-Dose Spironolactone Reduces XPB Expression and Induces Toxicity., PMID:34909723

Model-Informed Optimization of a Pediatric Clinical Pharmacokinetic Trial of a New Spironolactone Liquid Formulation., PMID:34201093

Polymeric micelle mediated follicular delivery of spironolactone: Targeting the mineralocorticoid receptor to prevent glucocorticoid-induced activation and delayed cutaneous wound healing., PMID:34090990

The Role of the Mineralocorticoid Receptor and Mineralocorticoid Receptor-Directed Therapies in Heart Failure., PMID:34050730

Novel polar AhR-active chemicals detected in sediments of an industrial area using effect-directed analysis based on in vitro bioassays with full-scan high resolution mass spectrometric screening., PMID:34030261

Effects of Impeller Geometry on the 11α-Hydroxylation of Canrenone in Rushton Turbine-Stirred Tanks., PMID:34024892

Aldosterone Is Positively Associated With Circulating FGF23 Levels in Chronic Kidney Disease Across Four Species, and May Drive FGF23 Secretion Directly., PMID:33995120

Mineralocorticoid Receptor Antagonist Effect on Aldosterone to Renin Ratio in Patients With Primary Aldosteronism., PMID:33942084

Assessing Adherence to Antihypertensive Medication by Means of Dose-Dependent Reference Plasma Concentration Ranges and Ultra-High Performance Liquid Chromatography-Ion Trap Mass Spectrometry Analysis., PMID:33803489

Underestimated reactions and regulation patterns of adrenal cytochromes P450., PMID:33722664

Primary aldosteronism: considerations about the evaluation of the aldosterone to renin ratio during canrenone treatment., PMID:33454931

Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic kidney disease., PMID:33107592

The Efficacy of the Mineralcorticoid Receptor Antagonist Canrenone in COVID-19 Patients., PMID:32933039

Preclinical study of simultaneous pharmacokinetic and pharmacodynamic herb-drug interactions between Yin-Chen-Hao-Tang and spironolactone., PMID:32799863

Ethanolic extract of Artemisia campestris subsp. glutinosa (Besser) Batt. inhibits HIV-1 replication in vitro through the activity of terpenes and flavonoids on viral entry and NF-κB pathway., PMID:32758575

Improved 11α-hydroxycanrenone production by modification of cytochrome P450 monooxygenase gene in Aspergillus ochraceus., PMID:32697747

Simultaneous determination of canrenone, digoxin and tolvaptan by UHPLC-MS/MS: application in heart failure patients., PMID:32469241

Assessment of adherence to diuretics and β-blockers by serum drug monitoring in comparison to urine analysis., PMID:32400211

Clinical efficacy of potassium canreonate-canrenone in sinus rhythm restoration among patients with atrial fibrillation - a protocol of a pilot, randomized, double -blind, placebo-controlled study (CANREN-AF trial)., PMID:32398047

Spironolactone metabolite concentrations in decompensated heart failure: insights from the ATHENA-HF trial., PMID:32237012

Effects of Mineralocorticoid and AT1 Receptor Antagonism on The Aldosterone-Renin Ratio In Primary Aldosteronism-the EMIRA Study., PMID:32067030

Datasheet
$ 160
Product specifications
100 μg 160 1 mg 800

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Canrenone/CRN, OVA conjugated [SGK61516]
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