Catalog No.
AQE07701
Biological activity
Measured in a cell proliferation assay using human erythroleukemic cells (TF‑1). The ED50 for this effect is 0.75-3.75 ng/mL.
Expression system
E. coli
Species
Canis lupus familiaris (Dog) (Canis familiaris)
Protein length
Ser19-Arg131
Nature
Recombinant
Endotoxin level
<1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9N0W9
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IL13, NC30, Interleukin-13, IL-13, Drug Target
Revealing the mechanism of Sanfu Patch dorsal application for alleviating OVA-induced asthma: an integrated approach combining TMT quantitative proteomics and molecular docking., PMID:40280374
Toll-like receptor 2 activation induces C-C motif chemokine ligand 5 production in canine keratinocytes., PMID:39973011
Unveiling the Interplay Between Dendritic Cells and Natural Killer Cells as Key Players in Leishmania Infection., PMID:39963187
Reconstructed Epidermis Produced with Atopic Dog Keratinocytes Only Exhibit Skin Barrier Defects after the Addition of Proinflammatory and Allergic Cytokines., PMID:39811760
Analysis of the immunomodulatory properties of mycobacterium cell wall fraction on the cytokine production of peripheral blood mononuclear cells of healthy dogs., PMID:39140285
Sangju Cold Granule exerts anti-viral and anti-inflammatory activities against influenza A virus in vitro and in vivo., PMID:38969152
Oclacitinib (APOQUEL®) is a selective Janus kinase 1 inhibitor with efficacy in a canine model of flea allergic dermatitis., PMID:38926932
Canine peripheral non-conventional TCRαβ+ CD4-CD8α- double-negative T cells show T helper 2-like and regulatory properties., PMID:38835756
Investigation of the relationship between atopic dermatitis of dogs and intestinal epithelial damage., PMID:38648253
A novel quinoline with airway relaxant effects and anti-inflammatory properties., PMID:38555460
In vitro immunoregulatory role of recombinant Ancylostoma ceylanicum calreticulin., PMID:38443772
Characterization of the serum and skin inflammatory profile in canine pemphigus foliaceus using multiplex assay and quantitative real-time polymerase chain reaction (qRT-PCR)., PMID:37473673
Cytokine transcriptome profiling in acute experimental canine atopic dermatitis skin lesions after IL-31 inhibition with lokivetmab., PMID:37006124
Haematological indices and immune response profiles in dogs naturally infected and co-infected with Dirofilaria repens and Babesia canis., PMID:36739305
Mesenchymal Stem Cells and Extracellular Vesicles Derived from Canine Adipose Tissue Ameliorates Inflammation, Skin Barrier Function and Pruritus by Reducing JAK/STAT Signaling in Atopic Dermatitis., PMID:35563259
Immunological mechanisms involved in the human response to a dog dander allergoid., PMID:35306358
Expression and biological functions of Ancylostoma ceylanicum saposin-like protein., PMID:34546437
Epithelial-immune crosstalk with the skin microbiota in homeostasis and atopic dermatitis - a mini review., PMID:34378246
Expression of barrier proteins in the skin lesions and inflammatory cytokines in peripheral blood mononuclear cells of atopic dogs., PMID:34075152
The proprotein convertase furin inhibits IL-13-induced inflammation in airway smooth muscle by regulating integrin-associated signaling complexes., PMID:34009050
Effect of chemically modified tetracycline-8 (CMT-8) on hematology, blood chemistry, cytokines and peripheral blood lymphocyte subsets of healthy dogs., PMID:33684794
Phase I trial of convection-enhanced delivery of IL13RA2 and EPHA2 receptor targeted cytotoxins in dogs with spontaneous intracranial gliomas., PMID:32812637
Association analysis of non-synonymous polymorphisms of interleukin-4 receptor-α and interleukin-13 genes in canine atopic dermatitis., PMID:32669513
S100A4 is secreted by airway smooth muscle tissues and activates inflammatory signaling pathways via receptors for advanced glycation end products., PMID:32432920
Effect of Ancylostoma ceylanicum hookworm platelet inhibitor on platelet adhesion and peripheral blood mononuclear cell proliferation., PMID:32300877
Sequential Histopathological Changes and Cytokine Expressions in Dogs Naturally Infested with Sarcoptes scabiei Mites., PMID:32100229
Urinary proteome of dogs with kidney injury during babesiosis., PMID:31801572
Interleukin-13 and interleukin-33 mRNA are underexpressed in the duodenal mucosa of German Shepherd dogs with chronic enteropathy., PMID:31169944
Evaluation of immunological parameters in pit bull terrier-type dogs with juvenile onset generalized demodicosis and age-matched healthy pit bull terrier-type dogs., PMID:30141276
Cytokine Profile of Leishmania Infantum Fucose-Mannose Ligand in Vaccinated Dogs in the Northwest of Iran., PMID:29276182
Transcriptional analysis of the IL-33 receptor suppression of tumourigenicity 2 and its effects on canine Type 2 T helper cells: a preliminary study., PMID:29178475
A study on periostin involvement in the pathophysiology of canine atopic skin., PMID:29176263
Focal adhesion kinase (FAK) and mechanical stimulation negatively regulate the transition of airway smooth muscle tissues to a synthetic phenotype., PMID:27612967
Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitis., PMID:27553600
IL-4 downregulates expression of the target receptor CD30 in neoplastic canine mast cells., PMID:27507155
Early Activation of Th2/Th22 Inflammatory and Pruritogenic Pathways in Acute Canine Atopic Dermatitis Skin Lesions., PMID:27342734
Cross-reactivity of commercially available anti-human monoclonal antibodies with canine cytokines: establishment of a reliable panel to detect the functional profile of peripheral blood lymphocytes by intracytoplasmic staining., PMID:26362860
Allergenic Can f 1 and its human homologue Lcn-1 direct dendritic cells to induce divergent immune responses., PMID:26218644
New insights into the immunopathology of early Toxocara canis infection in mice., PMID:26135397
New dog and new tricks: evolving roles for IL-33 in type 2 immunity., PMID:25801770
CD4+ and CD8+ skin-associated T lymphocytes in canine atopic dermatitis produce interleukin-13, interleukin-22 and interferon-γ and contain a CD25+ FoxP3+ subset., PMID:24913127
Preferential gene transcription of T helper 2 cytokines in peripheral CCR4(+) CD4(+) lymphocytes in dogs., PMID:24840326
Oclacitinib (APOQUEL(®)) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy., PMID:24495176
The immunostimulatory effect of CpG oligodeoxynucleotides on peripheral blood mononuclear cells of healthy dogs and dogs with atopic dermatitis., PMID:24461202
New agents for targeting of IL-13RA2 expressed in primary human and canine brain tumors., PMID:24147065
Dogs immunized with LBSap vaccine displayed high levels of IL-12 and IL-10 cytokines and CCL4, CCL5 and CXCL8 chemokines in the dermis., PMID:23911411
Assessment of circulating concentrations of proinflammatory and anti-inflammatory cytokines and nitric oxide in dogs with brachycephalic airway obstruction syndrome., PMID:23270361
Signal transducer and activator of transcription-6 (STAT6) inhibition suppresses renal cyst growth in polycystic kidney disease., PMID:22025716
Gene transcription analysis in lesional skin of canine epitheliotropic cutaneous lymphoma using quantitative real-time RT-PCR., PMID:21945178
Lesional skin in atopic dogs shows a mixed Type-1 and Type-2 immune responsiveness., PMID:21684616
For research use only. Not for human or drug use.
