Catalog No.
AHH04601
Biological activity
Immobilized recombinant human Nectin-3 at 2 μg/mL (100 μL/well) can bind recombinant human CD111/NECTIN1 (Cat #: AHH04601) with a linear range of 30-122 ng/mL.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Thr334
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15223
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Herpesvirus entry mediator C, CD111, Herpes virus entry mediator C, HIgR, Poliovirus receptor-related protein 1, PRR1, NECTIN1, Nectin cell adhesion molecule 1, Nectin-1, HveC, HVEC, Herpesvirus Ig-like receptor, PVRL1
Identification of NECTIN1 as a novel restriction factor for flavivirus infection., PMID:39570015
Clostridioides difficile S-Layer Protein A (SlpA) Serves as a General Phage Receptor., PMID:36790200
Does size matter? Two new deletions in the HBB gene cause β0-thalassemia., PMID:35467101
Poliovirus receptor (PVR)-like protein cosignaling network: new opportunities for cancer immunotherapy., PMID:34433460
Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression., PMID:30224769
Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex viruses., PMID:26188016
The Clostridium difficile cell wall protein CwpV confers phase-variable phage resistance., PMID:26179020
Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of pediatric solid tumors., PMID:24497984
Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of neuroblastoma., PMID:24130898
Assessment of genetic markers and glioblastoma stem-like cells in activation of dendritic cells., PMID:23737374
Engineered herpes simplex viruses efficiently infect and kill CD133+ human glioma xenograft cells that express CD111., PMID:19521665
Role for plasmacytoid dendritic cells in the immune control of recurrent human herpes simplex virus infection., PMID:19073735
Comparative usage of herpesvirus entry mediator A and nectin-1 by laboratory strains and clinical isolates of herpes simplex virus., PMID:15110526
Cellular localization of nectin-1 and glycoprotein D during herpes simplex virus infection., PMID:12885915
Functional characterization of human CD34+ cells that express low or high levels of the membrane antigen CD111 (nectin 1)., PMID:12764381
[Leukocyte adhesion: a fundamental process in immunologic and inflammatory reactions]., PMID:1999969
For research use only. Not for human or drug use.
